Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daniel M. Bürgisser"'
Autor:
Beat Thöny, Claus W. Heizmann, Daniel M. Bürgisser, Nenad Blau, Tanja Oppliger, Herbert Nar, Robert Huber
Publikováno v:
Journal of Biological Chemistry. 270:29498-29506
Four naturally occurring mutants with single amino acid alterations in human 6-pyruvoyltetrahydropterin synthase (PTPS) were overexpressed and characterized in vitro. The corresponding DNA mutations were found in patients with hyperphenylalaninemia a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0188b55951529cf22e2cb97ca8934306
https://doi.org/10.1074/jbc.270.49.29498
https://doi.org/10.1074/jbc.270.49.29498
Publikováno v:
Biochemical and Biophysical Research Communications. 189:1437-1443
6-Pyruvoyl-tetrahydropterin synthase (PTPS) is involved in the biosynthesis of tetrahydrobiopterin (BH4), an essential cofactor for enzymes such as the hepatic phenylalanine hydroxylase. BH4 deficiency causes malignant hyperphenylalaninemia. We clone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c868a83c5540871bbf548f54df7fa25b
https://doi.org/10.1016/0006-291x(92)90235-d
https://doi.org/10.1016/0006-291x(92)90235-d
Autor:
R.E. Humbel, Birgit V. Roth, S Weigl, Daniel M. Bürgisser, Roman J. Giger, Christine Lüthi, J Zarn
Publikováno v:
Journal of Biological Chemistry. 266:1029-1033
With the aim to produce insulin-like growth factors (IGF) with enhanced specificity for the type 1 or type 2 IGF receptors, three mutants of IGF II have been prepared and expressed in NIH-3T3 cells. IGF II mutated at Tyr27 to Leu and Glu showed a 25-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6712f2ebed08974a0a2ec5fec70d546a
https://doi.org/10.1016/s0021-9258(17)35278-x
https://doi.org/10.1016/s0021-9258(17)35278-x
Autor:
Florence Guignard, Neil Birchler, Evelyn C. Ilg, Daniel M. Bürgisser, Michèle Markert, Heinz Troxler, Peter Hunziker, Claus W. Heizmann, Thomas Kuster
Publikováno v:
Biochemical and biophysical research communications. 225(1)
S100A12 has been isolated from human neutrophils. The molecular weight and the amino acid sequence of S100A12 was determined by electrospray-mass spectrometry, tandem mass spectrometry and Edman microsequence analysis. Interestingly, a sequence compa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7947f314c44c1fe3200a38ddab226f
https://pubmed.ncbi.nlm.nih.gov/8769108
https://pubmed.ncbi.nlm.nih.gov/8769108
Autor:
Claus W. Heizmann, G. Siegenthaler, U. Hellman, Peter Hunziker, Daniel M. Bürgisser, Neil Birchler, Thomas Kuster
Publikováno v:
Biochemical and biophysical research communications. 217(1)
The Ca(2+)-binding proteins regulate a number of cellular and extracellular activities and deregulations of S100 gene expression are associated with several human diseases. For example, S100A7 is upregulated in psoriatic skin, implicating a link with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e7a9e1fe96bcbfb85d6a98c2e3e8bf
https://pubmed.ncbi.nlm.nih.gov/8526920
https://pubmed.ncbi.nlm.nih.gov/8526920
Autor:
Herbert Nar, Claus W. Heizmann, Daniel M. Bürgisser, Beat Thöny, U. Redweik, Daniel Hess, Robert Huber
Publikováno v:
Journal of molecular biology. 253(2)
6-Pyruvoyl tetrahydropterin synthase (PTPS) is an enzyme involved in tetrahydrobiopterin biosynthesis, the cofactor for several aromatic aminoacid monooxygenases and the nitric oxide synthases. The crystal structure of PTPS was recently solved and sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a6cbcac8e7d85e482a0e15574fbe97
https://pubmed.ncbi.nlm.nih.gov/7563095
https://pubmed.ncbi.nlm.nih.gov/7563095
Publikováno v:
European journal of biochemistry. 219(1-2)
6-Pyruvoyl-tetrahydropterin synthase is the rate-limiting enzyme in the synthesis of human tetrahydrobiopterin, a cofactor for several hydroxylases involved in catecholamine and serotonin biosynthesis. The human and rat liver cDNAs encoding the 16-kD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e77eadc68da639135f575f2609d8a741
https://pubmed.ncbi.nlm.nih.gov/8307017
https://pubmed.ncbi.nlm.nih.gov/8307017
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461362876
Tetrahydrobiopterin (BH4) is the coenzyme for several monooxygenases such as the aromatic amino acid hydroxylases, the glycerol ether monooxygenase, and the nitric oxide synthases1,2. A lack of BH4 leads to hyperphenylalaninemia and a deficiency of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e10e8aef2f8f4e0500ddfbdd306434ab
https://doi.org/10.1007/978-1-4615-2960-6_37
https://doi.org/10.1007/978-1-4615-2960-6_37
Publikováno v:
Biochemical and biophysical research communications. 181(2)
Five structural analogs of human insulin-like growth factor II (IGF II), [Leu27]IGF II, [Glu27]IGF II, des(62–67)IGF II, des(62–67)[Leu27]IGF II and des(62–67)[Glu27]IGF II were constructed by site-directed mutagenesis and expressed as protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8c9db442d096988c141d9ac6dda691
https://pubmed.ncbi.nlm.nih.gov/1721812
https://pubmed.ncbi.nlm.nih.gov/1721812
Preparation and characterization of polyclonal and monoclonal antibodies against the insecticide DDT
Publikováno v:
Biochemical and biophysical research communications. 166(3)
A synthetic DDT derivative in which the molecular structure of DDT was completely retained was coupled to bovine serum albumin. Animals were immunized with the DDT-bovine serum albumin conjugate and polyclonal and monoclonal antibodies against the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c51317f5a86f660c7f294ef8f530ee
https://pubmed.ncbi.nlm.nih.gov/2306239
https://pubmed.ncbi.nlm.nih.gov/2306239