Disruptions in endocytic traffic contribute to the activation of the NLRP3 inflammasome

Autor: Bali Lee, Christopher Hoyle, Rose Wellens, Jack P. Green, Fatima Martin-Sanchez, Daniel M. Williams, Billie J. Matchett, Paula I. Seoane, Hayley Bennett, Antony Adamson, Gloria Lopez-Castejon, Martin Lowe, David Brough

Publikováno v: Lee, B, Hoyle, C, Wellens, R, Green, J P, Martin-Sanchez, F, Williams, D M, Matchett, B J, Seoane, P I, Bennett, H, Adamson, A, Lopez-Castejon, G, Lowe, M & Brough, D 2023, ' Disruptions in endocytic traffic contribute to the activation of the NLRP3 inflammasome ', Science Signaling, vol. 16, no. 773 . https://doi.org/10.1126/scisignal.abm7134

Inflammation driven by the NLRP3 inflammasome is coordinated through multiple signaling pathways and is regulated by subcellular organelles. Here, we tested the hypothesis that NLRP3 senses disrupted endosome trafficking to trigger inflammasome forma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af561ca983c5ec69eee329df91be13e
https://doi.org/10.1126/scisignal.abm7134

Assessment of endocytic traffic and Ocrl function in the developing zebrafish neuroepithelium

Autor: Daniel M. Williams, Lale Gungordu, Anthony Jackson-Crawford, Martin Lowe

Publikováno v: Williams, D M, Gungordu, L, Jackson-Crawford, A & Lowe, M 2022, ' Assessment of endocytic traffic and Ocrl function in the developing zebrafish neuroepithelium ', Journal of Cell Science, vol. 135, no. 18, jcs260339 . https://doi.org/10.1242/jcs.260339

Endocytosis is a vital process, required during development and for maintenance of tissue homeostasis, that allows cells to internalize a wide range of molecules from their environment as well maintain their plasma membrane composition. The ability t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707940cf61326c71a0831049f5e190c6
https://doi.org/10.1242/jcs.260339

Paroxysmal Hypnogenic Dyskinesia Responsive to Doxylamine: A Case Report

Autor: Daniel M. Williams

Publikováno v: Case Reports in Neurological Medicine, Vol 2012 (2012)

Paroxysmal hypnogenic dyskinesia is a rare clinical entity characterized by intermittent dystonia and choreoathetoid movements that begin exclusively during sleep, often with consciousness preserved once the patient is awakened during the episodes. T

Externí odkaz: https://doaj.org/article/0aeab86523cf471fa423f9a7af115146

Implementation Of A Community Psychological Treatment Program For Military Families: Project Homefront

Autor: Jack Y Tsan, Daniel M Williams

Publikováno v: The International Journal of Social Sciences and Humanities Invention.

Demand for psychological services by the U.S. military population has outpaced supply in recent years. Despite record growth within the government health care systems in this area, roughly half of veterans have sought any healthcare within the Vetera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::59afedc3a3d23497e992f96df31e10ef
https://doi.org/10.18535/ijsshi/v3i4.01

Small Aircraft Transportation System, Higher Volume Operations Concept and Research Summary

Autor: Daniel M. Williams, Maria C. Consiglio, Brian T. Baxley, Terence S. Abbott, Catherine Adams

Publikováno v: Journal of Aircraft. 45:1825-1834

The ability to conduct concurrent, multiple aircraft operations in poor weather at virtually any airport offers an important opportunity for a significant increase in the rate of flight operations, a major improvement in passenger convenience, and th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa19aae4461a9d724a20a41d55a7843a
https://doi.org/10.2514/1.20493