Blood levels of S-100 calcium-binding protein B, high-sensitivity C-reactive protein, and interleukin-6 for changes in depressive symptom severity after coronary artery bypass grafting: prospective cohort nested within a randomized, controlled trial.

Autor: Daniel M Pearlman, Jeremiah R Brown, Todd A MacKenzie, Felix Hernandez, Souhel Najjar

Publikováno v: PLoS ONE, Vol 9, Iss 10, p e111110 (2014)

BACKGROUND: Cross-sectional and retrospective studies have associated major depressive disorder with glial activation and injury as well as blood-brain barrier disruption, but these associations have not been assessed prospectively. Here, we aimed to

Externí odkaz: https://doaj.org/article/f2ac8525b0fe455b85b3741656c716da

Neuroinflammation and white matter pathology in schizophrenia: systematic review

Autor: Daniel M. Pearlman, Souhel Najjar

Publikováno v: Schizophrenia Research. 161:102-112

Background Neuroinflammation and white matter pathology have each been independently associated with schizophrenia, and experimental studies have revealed mechanisms by which the two can interact in vitro, but whether these abnormalities simultaneous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f5c3d9ad1d984ae9a99f5ec5033b3d
https://doi.org/10.1016/j.schres.2014.04.041

Brain Biopsy Findings Link Major Depressive Disorder to Neuroinflammation, Oxidative Stress, and Neurovascular Dysfunction: A Case Report

Autor: Jason Reidy, Kent Friedman, Richard B. Ferrell, Daniel M. Pearlman, John Strange, Amanda Najjar, Orrin Devinsky, Maya T Khoukaz, Scott Hirsch, Souhel Najjar, David Zagzag

Publikováno v: Biological Psychiatry. 75:e23-e26

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4920452716a805124767897df5a56877
https://doi.org/10.1016/j.biopsych.2013.07.041

Meta-Analysis of Individual Patient Data of Sodium Bicarbonate and Sodium Chloride for All-Cause Mortality After Coronary Angiography

Autor: Lisette Okkels Jensen, Daniel M. Pearlman, Jeremiah R. Brown, Vitor Osório Gomes, Shama S. Alam, Emily J. Marshall, Alejandro Recio-Mayoral, Bokyung Kim, Todd A. MacKenzie, Mauro Maioli, Christian Mueller, Richard Solomon

Publikováno v: Brown, R J, Pearlman, D M, Marshall, E J, Alam, S, MacKenzie, T A, Recio-Mayoral, A, Gomes, V O, Kim, B, Jensen, L O, Mueller, C, Maioli, M & Solomon, R J 2016, ' Meta-Analysis of Individual Patient Data of Sodium Bicarbonate and Sodium Chloride for All-Cause Mortality After Coronary Angiography ', American Journal of Cardiology, vol. 118, no. 10, pp. 1473-1479 . https://doi.org/10.1016/j.amjcard.2016.08.008

We sought to examine the relation between sodium bicarbonate prophylaxis for contrast-associated nephropathy (CAN) and mortality. We conducted an individual patient data meta-analysis from multiple randomized controlled trials. We obtained individual

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8519b8a8f8d462ca5fe621793de35ece
https://hdl.handle.net/10668/10456

Refractory Epilepsy Associated With Microglial Activation

Autor: Souhel Najjar, Daniel M. Pearlman, Orrin Devinsky, Douglas C. Miller

Publikováno v: The Neurologist. 17:249-254

BACKGROUND Experimental and clinical studies support a pathogenic role of microglial activation and proliferation (MAP) in epileptogenesis. METHODS From a consecutive series of 319 surgically treated epilepsy cases, we retrospectively reviewed the hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d68bc270518c54a529f2350ae6400691
https://doi.org/10.1097/nrl.0b013e31822aad04