Zobrazeno 1 - 7 of 7 pro vyhledávání: '"Daniel Longley"'
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Akademický článek
Apoptotic and Necroptotic Mediators are Differentially Expressed in Mucinous and Non-Mucinous Colorectal Cancer
Autor: Emer O’Connell, Ian S. Reynolds, Andreas U. Lindner, Manuela Salvucci, Tony O’Grady, Orna Bacon, Sanghee Cho, Elizabeth McDonough, Daniel Longley, Fiona Ginty, Deborah A. McNamara, John P. Burke, Jochen H. M. Prehn
Publikováno v: Frontiers in Oncology, Vol 12 (2022)
BackgroundMucinous colorectal cancer (CRC) represents 10% of all CRC and is associated with chemotherapy resistance. This study aimed to determine expression of apoptosis and necroptosis mediators in mucinous CRC.MethodsRNA gene expression data were
Externí odkaz: https://doaj.org/article/24053e31c1834f909ac0a7c4bff31715
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Multiplexed Immunofluorescence Imaging Reveals an Immune Rich Tumor Microenvironment in Mucinous Rectal Cancer Characterized by Increased Lymphocyte Infiltration and Enhanced PD-1 Expression
Autor: William P. Duggan, Batuhan Kisakol, Emer O’Connell, Anna Matveeva, Tony O’Grady, Elizabeth McDonough, Andreas U. Lindner, Deborah McNamara, Daniel Longley, Fiona Ginty, John P. Burke, Jochen H. M. Prehn
Publikováno v: Diseases of the colon and rectum.
Mucinous rectal cancer is associated with a higher incidence of microsatellite instability, and a poorer response to neoadjuvant chemoradiotherapy compared to other subtypes of rectal adenocarcinoma. Immune checkpoint inhibitors are an emerging famil
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bbdad0ec5781b8557689f7192d479e3
https://pubmed.ncbi.nlm.nih.gov/36525395
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4
Abstract B4: Elevated expression of c-FLIP in castrate-resistant prostate cancer antagonizes response to androgen receptor-targeted therapy
Autor: Joe O'Sullivan, Rodolfo Montironi, Roberta Mazzucchelli, Clare McCourt, Daniel Longley, David Waugh, Pamela Maxwell, Manuel Salto-Tellez, Marina Scarpelli
Publikováno v: Cancer Research. 72:B4-B4
Cellular Fas-associated death domain (FADD)-like interleukin 1β-converting enzyme (FLICE) inhibitory protein (c-FLIP) is a key inhibitor of caspase 8 (FLICE)-promoted apoptosis. We have previously shown c-FLIP to be a transcriptional target of the a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::579a5c770a38692b1d53cad5e250ddd9
https://doi.org/10.1158/1538-7445.prca2012-b4
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5
Akademický článek
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