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pro vyhledávání: '"Daniel Lill"'
Autor:
Daniel Lill, Anne Kümmel, Venelin Mitov, Daniel Kaschek, Nathalie Gobeau, Henning Schmidt, Jens Timmer
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 4, Pp 512-523 (2022)
Abstract Simulation of combination therapies is challenging due to computational complexity. Either a simple model is used to simulate the response for many combinations of concentration to generate a response surface but parameter variability and un
Externí odkaz:
https://doaj.org/article/d297c53fa9a14a1691c16fe7a86e1619
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217837 (2019)
When non-linear models are fitted to experimental data, parameter estimates can be poorly constrained albeit being identifiable in principle. This means that along certain paths in parameter space, the log-likelihood does not exceed a given statistic
Externí odkaz:
https://doaj.org/article/8a81145b3d5d4d89a5e967fdfbe61869
Autor:
Anthony James Mc Elwee, Daniel Lill, Boris N. Kholodenko, Oleksii S. Rukhlenko, Eugene Kashdan, Jens Timmer
Publikováno v:
npj Systems Biology and Applications
npj Systems Biology and Applications, Vol 5, Iss 1, Pp 1-11 (2019)
NPJ Systems Biology and Applications
npj Systems Biology and Applications, Vol 5, Iss 1, Pp 1-11 (2019)
NPJ Systems Biology and Applications
Modular Response Analysis (MRA) is a suite of methods that under certain assumptions permits the precise reconstruction of both the directions and strengths of connections between network modules from network responses to perturbations. Standard MRA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfa77c56a327ef269a860eebdaad121
Autor:
Daniel Lilley, Peter Munthali
Publikováno v:
Infection Prevention in Practice, Vol 4, Iss 4, Pp 100240- (2022)
Summary: Background: Ventriculitis is an infection of the ventricular system of the central nervous system associated with neurosurgery and/or indwelling medical devices mainly caused by coagulase-negative staphylococci and increasingly by Gram-negat
Externí odkaz:
https://doaj.org/article/10eb40187bca403a92bed8359a1c9ebb
Autor:
Eleanor M. Townsend, Lucy Kelly, George Muscatt, Joshua D. Box, Nicole Hargraves, Daniel Lilley, Eleanor Jameson
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
The investigation of the microbial populations of the human body, known as the microbiome, has led to a revolutionary field of science, and understanding of its impacts on human development and health. The majority of microbiome research to date has
Externí odkaz:
https://doaj.org/article/14b76b2572884ecfb3149bfb87a13ed9