Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Daniel Lightwood"'
Autor:
Clare S. Hardman, Yi-Ling Chen, Marcin Wegrecki, Soo Weei Ng, Robert Murren, Davinderpreet Mangat, John-Paul Silva, Rebecca Munro, Win Yan Chan, Victoria O’Dowd, Carl Doyle, Prashant Mori, Andy Popplewell, Jamie Rossjohn, Daniel Lightwood, Graham S. Ogg
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Skin inflammation is often accompanied by systemic disease, yet the pathways that regulate this escalation are little known. Here authors show that transgenic expression of human CD1a in mice leads to the escalation of experimental skin inflammation
Externí odkaz:
https://doaj.org/article/8f36ea19ce9a4285881dcc232935ca78
Autor:
Daniel, Lightwood, Victoria, O'Dowd, Bruce, Carrington, Vaclav, Veverka, Mark D, Carr, Markus, Tservistas, Alistair J, Henry, Bryan, Smith, Kerry, Tyson, Sabrina, Lamour, Marguerite, Bracher, Kaushik, Sarkar, Alison, Turner, Alastair D, Lawson, Tim, Bourne, Neil, Gozzard, Roger, Palframan
Publikováno v:
Journal of Molecular Biology. 425:577-593
We describe the discovery, engineering and characterisation of a highly potent anti-human interleukin (IL)-13 Fab fragment designed for administration by inhalation. The lead candidate molecule was generated via a novel antibody discovery process, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e220d3deb7766a555a5341b5e3028cc5
https://doi.org/10.1016/j.jmb.2012.11.036
https://doi.org/10.1016/j.jmb.2012.11.036
Publikováno v:
Inflammatory bowel diseases. 13(2)
Intestinal inflammation associated with inflammatory bowel disease (IBD) is typically characterized by an inflammatory cell infiltrate and pro-inflammatory cytokine production. Of particular interest, the frequency of colony stimulating factor-1 (CSF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e56fe45dd7a35812bea0f4edd66c1396
https://pubmed.ncbi.nlm.nih.gov/17206685
https://pubmed.ncbi.nlm.nih.gov/17206685