Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Daniel Lakatos"'
Autor:
Melanie Maier, Linus Weiß, Nikolas Zeh, Valerie Schmieder-Todtenhaupt, Alireza Dehghani, Marius Nicolaus Felix, Daniel Heinzelmann, Benjamin Lindner, Moritz Schmidt, Joey Studts, Patrick Schulz, Bernd Reisinger, Kerstin Otte, Matthias Franzreb, Daniel Lakatos, Simon Fischer
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Monoclonal antibodies (mAb) and other biological drugs are affected by enzymatic polysorbate (PS) degradation that reduces product stability and jeopardizes the supply of innovative medicines. PS represents a critical surfactant stabilizing the activ
Externí odkaz:
https://doaj.org/article/25ff403b4f7d467a92c72862afa44c17
Publikováno v:
Journal of Chromatography B. 1174:122717
The enzymatic hydrolysis of polysorbates, e.g. induced by specific host cell proteins in biologics, is a known risk factor regarding the potential particle formation in the product over time. One of the root causes for this observation is an increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5265142b210a300d1c506573ae164d
https://doi.org/10.1016/j.jchromb.2021.122717
https://doi.org/10.1016/j.jchromb.2021.122717
Publikováno v:
Key Engineering Materials. 601:45-49
This paper presents the evaluation of residual stresses and stresses induced by external loads in a water drinker by numerical and experimental methods. The part, used in animal husbandry, is made of grey cast iron (EN GJL 200). Numerical simulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86a2cac037f85d5d951176a646274b32
https://doi.org/10.4028/www.scientific.net/kem.601.45
https://doi.org/10.4028/www.scientific.net/kem.601.45