Výsledky vyhledávání - "Daniel L. Stoler"

Restoration of DNA-binding and growth-suppressive activity of mutant forms of p53 via a PCAF-mediated acetylation pathway

Autor: Vamsi K. Kolukula, Jason Catania, Adolf Graessmann, Michael J. Pishvaian, Christopher Albanese, Daniel L. Stoler, Chad D. Knights, Geetaram Sahu, Ricardo E. Perez, Maria Laura Avantaggiati, Vasily Ogryzko

Publikováno v: Journal of Cellular Physiology. 225:394-405

Tumor-derived mutant forms of p53 compromise its DNA binding, transcriptional, and growth regulatory activity in a manner that is dependent upon the cell-type and the type of mutation. Given the high frequency of p53 mutations in human tumors, reacti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5f612ee1881b74b578c93fcaa26ccfc
https://doi.org/10.1002/jcp.22285

Zobrazit plný text záznamu

Chronic Periodontitis and the Incidence of Head and Neck Squamous Cell Carcinoma

Autor: Andrew Hyland, Mihai Merzianu, Jean Wactawski-Wende, James R. Marshall, Thom R. Loree, Linda Hauck, Cheryl Lillis, Maureen Sullivan, Mary E. Reid, Daniel L. Stoler, Mine Tezal, Frank A. Scannapieco, Nestor R. Rigual

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 18:2406-2412

Substantial evidence supports an association between chronic infections/inflammation, and cancer. The aim of this study was to assess the effect of chronic periodontitis on head and neck squamous cell carcinoma (HNSCC). The study population consisted

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68a8113d8f647e6084f18909d7c3b289
https://doi.org/10.1158/1055-9965.epi-09-0334

Zobrazit plný text záznamu

Genomic profiles of colorectal cancers differ based on patient smoking status

Autor: Garth R. Anderson, K. Michael Cummings, Sam M. Wiseman, Nicholas J. Petrelli, Daniel L. Stoler, Neng Chen, Nachimuthu Natarajan, Miguel A. Rodriguez-Bigas, Norma J. Nowak, Aasma Shaukat, Sadir Alrawi, Devin A. McQuaid, Jeremy D. Bartos, Smitha S. Dutt, Helen Swede, Bruce M. Brenner

Publikováno v: Cancer Genetics and Cytogenetics. 168:98-104

Human sporadic colorectal cancer is the result of a lengthy somatic evolutionary process facilitated by various forms of genomic instability. Such instability arises endogenously from mutations in genes whose role is to preserve genomic integrity, an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::220d875aeb662535c84ec46539539018
https://doi.org/10.1016/j.cancergencyto.2006.02.009

Zobrazit plný text záznamu

Genomic instability in invasive breast carcinoma measured by inter-Simple Sequence Repeat PCR

Autor: Daniel L. Stoler, Janet S. Winston, Helen Swede, Garth R. Anderson, Stephen B. Edge, Sam M. Wiseman, Jeremy D. Bartos

Publikováno v: Breast Cancer Research and Treatment. 97:107-110

We have measured genomic instability in invasive breast carcinomas and assessed the relationship of genomic instability to known tumor prognostic factors. DNAs from tumors and adjacent normal tissue of 18 breast cancer patients were subjected to inte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef22cf86186b04222e4407c4eb918b8
https://doi.org/10.1007/s10549-005-9092-9

Zobrazit plný text záznamu

Analysis of Inter-(Simple Sequence Repeat) PCR Products From Human Colorectal Cancers

Autor: Neng Chen, Daniel L. Stoler, Nicholas J. Petrelli, Smitha S. Dutt, Miguel A. Rodriguez-Bigas, Gerald P. Jahreis, Garth R. Anderson

Publikováno v: Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics. 15:233-238

Genomic instability is a fundamental characteristic of solid tumors, and understanding genomic instability should significantly clarify the process of tumorigenesis. We adapted the sampling technique of inter-(simple sequence repeat) PCR [inter-(SSR)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed94718563aa6ae8a51a3e59694cca18
https://doi.org/10.3727/096504005776382297

Zobrazit plný text záznamu

Definition of a Region of Loss of Heterozygosity at Chromosome 11q23.3-25 in Head and Neck Squamous Cell Carcinoma Using Laser Capture Microdissection Technique

Autor: Nestor R. Rigual, Daniel L. Stoler, Dongfeng Tan, Qiang Li, Pamela Ward, Youtai Zhou, Harry K. Slocum, Garth R. Anderson, Wesley L. Hicks, Sam M. Wiseman, Thom R. Loree, Sadir Alrawi

Publikováno v: Diagnostic Molecular Pathology. 13:33-40

To date, loss of heterozygosity (LOH) studies on HNSCC have had limited success in identifying a confined region of loss on chromosome 11q partially due to the heterogeneous nature of tumor tissue examined. Additionally, little is known about the rol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee5154598666606e1b2a63d1f616aeb
https://doi.org/10.1097/00019606-200403000-00006

Zobrazit plný text záznamu

Papillary thyroid cancer: High inter-(simple sequence repeat) genomic instability in a typically indolent cancer

Autor: Janet S. Winston, Wesley L. Hicks, Jeremy D. Bartos, Garth R. Anderson, Daniel L. Stoler, Sam M. Wiseman, Nestor R. Rigual, Thorn R. Loree, Helen Swede

Publikováno v: Head & Neck. 25:825-832

Objectives. The object of this study is to measure genomic instability in papillary thyroid cancer and correlate these measurements with known clinical prognosticators such as patient age, tumor size, histologic subtype, and three commonly used thyro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eea92c0181d36ea34ddd61028bef859b
https://doi.org/10.1002/hed.10292

Zobrazit plný text záznamu

Anaplastic transformation of thyroid cancer: Review of clinical, pathologic, and molecular evidence provides new insights into disease biology and future therapy

Autor: Thom R. Loree, Garth R. Anderson, Sam M. Wiseman, Nestor R. Rigual, Daniel L. Stoler, Wade G. Douglas, Wesley L. Hicks

Publikováno v: Head & Neck. 25:662-670

Background. Anaplastic thyroid cancer ranks among the most lethal of all human malignancies. Its rarity and rapidly fatal course have made it a difficult cancer to both study and treat. Unfortunately, there has been little progress in the management

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db267461ac7f00be4a73cf77b5754d2e
https://doi.org/10.1002/hed.10277

Zobrazit plný text záznamu

Cancer: the evolved consequence of a destabilized genome

Autor: Bruce M. Brenner, Garth R. Anderson, Daniel L. Stoler

Publikováno v: BioEssays. 23:1037-1046

The genome is a stable repository of vastly intricate genetic information developed over eons of evolution; this information is replicated at the highest fidelity and expressed within each cell at the highest selectivity. Non-leukemia cancers break t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd14040aff1bc296caf54946e8790b8
https://doi.org/10.1002/bies.1149

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání