Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daniel L. Parsons"'
Publikováno v:
Drug Development and Industrial Pharmacy. 38:571-576
This paper investigates the microneedle (MN) mediated in vitro transdermal iontophoretic delivery of prochlorperazine edisylate (PE) across dermatomed human skin. The Dermaroller™ induced microchannels were visualized using methylene blue staining
Autor:
William R. Ravis, E. M. Portman, S. C. R. Brown, Y.-J. Jean Lin, Richard Stahl, Daniel L. Parsons, E. Cox, R. Jayachandra Babu, K. Jones, Y.-H. Phillip Lee, J. Schumacher, S. H. Duran
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 32:388-392
Phenylbutazone (PBZ) is a nonsteroidal anti-inflammatory drug used in the treatment of chronic pain and arthritis. Topical and transdermal administration of PBZ would be beneficial in large animals in terms of minimizing gastro-intestinal ulcerations
Publikováno v:
Journal of Controlled Release. 85:73-81
The objective of this study was to develop sustained release Poloxamer 407 (P407) gel formulations of ceftiofur for treating foot infections in cattle. The formulations contained 25-35% (w/v) P407 alone or with polyvinyl pyrrolidone (PVP), carboxy me
Autor:
Virginia A. Davis, Vinod K. Radhakrishnan, Daniel L. Parsons, R. Jayachandra Babu, Sateeshkumar Sathigari
Publikováno v:
Journal of pharmaceutical sciences. 101(9)
The aim of this study was to improve the dissolution rate of efavirenz (EFV) by formulating a physically stable dispersion in polymers. Hot-melt extrusion (HME) was used to prepare solid solutions of EFV with Eudragit EPO (a low-glass transition poly
Publikováno v:
Drug development and industrial pharmacy. 37(5)
The objective of this study was to formulate genistein as a topical gel with various penetration enhancers for increased permeation and retention in human skin. The high performance liquid chromatography assay method was validated for precision and r
Publikováno v:
Journal of drug targeting. 18(9)
Transdermal iontophoretic delivery of selegiline hydrochloride (SH) across dermatomed human skin was studied. Electrochemical stability and various factors affecting the skin permeation were investigated. SH was stable under the influence of an elect
Autor:
William R. Ravis, Gurkishan Chadha, R. Jayachandra Babu, Vijay K. Rangari, Daniel L. Parsons, Y.-H. Phillip Lee, Nydeia Wright, Y.-J. Jean Lin, Sateesh Sathigari
Publikováno v:
Drug development and industrial pharmacy. 35(9)
Gefitinib, an anticancer drug, has an extremely low aqueous solubility, and its oral absorption is limited by its dissolution rate. The solubility and dissolution of gefitinib can be improved by complexation with cyclodextrins (CDs).Phase solubility
Autor:
Y-H. Phillip Lee, Daniel L. Parsons, Sateeshkumar Sathigari, Vijay K. Rangari, Gurkishan Chadha, Nydeia Wright, Oladiran Fasina, R. Jayachandra Babu
Efavirenz (EFV) is an oral antihuman immunodeficiency virus type 1 drug with extremely poor aqueous solubility. Thus, its gastrointestinal absorption is limited by the dissolution rate of the drug. The objective of this study was to characterize the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3777838004a5c0a990897a9592e25945
https://europepmc.org/articles/PMC2663670/
https://europepmc.org/articles/PMC2663670/
Publikováno v:
Drug Metabolism Reviews. 23:375-411
As a result of their ability to transport oxygen, PFC emulsions are being investigated for possible use in a wide variety of conditions. The recent FDA approval of F-DA to diminish myocardial ischemia during angioplasty is the first marketing approva
Autor:
Daniel L. Parsons
Publikováno v:
Biochemical Pharmacology. 35:1395-1397