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pro vyhledávání: '"Daniel L. Garaulet"'
SummaryThe survival and reproductive success of animals depends on the ability to harmonize their external behaviors with their internal states. For example, females conduct numerous social programs that are distinctive to virgins, compared to post-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0063e97eb1e232fa449221fef5ce3409
https://doi.org/10.1101/2020.12.16.423061
https://doi.org/10.1101/2020.12.16.423061
Publikováno v:
Cell reports
SUMMARY Virgin females of many species conduct distinctive behaviors, compared with post-mated and/or pregnant individuals. In Drosophila, this post-mating switch is initiated by seminal factors, implying that the default female state is virgin. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33039edb39be40905638b148844a315
https://pubmed.ncbi.nlm.nih.gov/34233178
https://pubmed.ncbi.nlm.nih.gov/34233178
Publikováno v:
Dev Cell
SummaryHow are diverse regulatory strategies integrated to impose appropriately patterned gene expression that underliein vivophenotypes? Here, we reveal how coordinated miRNA regulation and neural-specific alternative polyadenylation (APA) of a sing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25300b3b794ecc612e85e573560237c8
Autor:
Ernesto Sánchez-Herrero, Fernando Bejarano, Eric C. Lai, Daniel L. Garaulet, Douglas W. Allan, David M. Tyler, Piero Sanfilippo, Monica C. Castellanos
Publikováno v:
Developmental Cell. 29:635-648
Summary The Drosophila Bithorax complex (BX-C) Hox cluster contains a bidirectionally transcribed miRNA locus, and a deletion mutant (Δ mir ) lays no eggs and is completely sterile. We show these miRNAs are expressed and active in distinct spatial r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52ef8c313cd27108bbedf0bc223940a1
https://doi.org/10.1016/j.devcel.2014.04.023
https://doi.org/10.1016/j.devcel.2014.04.023
Autor:
K. Sun, Alexandra M Panzarino, Daniel L. Garaulet, Jiayu Wen, P. R. Hiesinger, Wu Li, Jenna L O'Neil, Michael W. Young, Eric C. Lai
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(12)
Circadian clocks enable organisms to anticipate and adapt to fluctuating environmental conditions. Despite substantial knowledge of central clock machineries, we have less understanding of how the central clock's behavioral outputs are regulated. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af1d3fa8e32ec659a0672d6e66363596
https://pubmed.ncbi.nlm.nih.gov/27013671
https://pubmed.ncbi.nlm.nih.gov/27013671
Autor:
Daniel L. Garaulet, Eric C. Lai
Publikováno v:
Mechanisms of development.
The study of Drosophila Hox genes, located in the Antennapedia complex (ANT-C) and Bithorax complex (BX-C), have provided fundamental insights into mechanisms of how the segments of the animal body plan are specified. Notably, even though the analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b06e87d280b4f6957c9bf288163cd52
https://pubmed.ncbi.nlm.nih.gov/26311219
https://pubmed.ncbi.nlm.nih.gov/26311219
Publikováno v:
Development. 133:4495-4506
The halteres and wings of Drosophila are homologous thoracic appendages, which share common positional information provided by signaling pathways. The activity in the haltere discs of the Ultrabithorax(Ubx) Hox gene establishes the differences betwee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28012051d7be490233d834f40179628c
https://doi.org/10.1242/dev.02609
https://doi.org/10.1242/dev.02609
Autor:
Raquel Martin, Nicolas Robine, Dong Wang, Peter Smibert, Daniel L. Garaulet, P. Robin Hiesinger, Fernando Bejarano, Eric C. Lai, Jr-Shiuan Yang, Diane Bortolamiol-Becet
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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Canonical animal microRNAs (miRNAs) are ∼22-nt regulatory RNAs generated by stepwise cleavage of primary hairpin transcripts by the Drosha and Dicer RNase III enzymes. We performed a genetic screen using an miRNA-repressed reporter in the Drosophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328433651eba006f4b1609fed247e634
http://hdl.handle.net/10261/127086
http://hdl.handle.net/10261/127086
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
The Hox genes specify different structures along the anteroposterior axis of bilaterians. They code for transcription factors including a conserved domain, the homeodomain, that binds DNA. The specificity of Hox function is determined by each gene co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98c06eab37f7754413983a6e59e15d3
http://hdl.handle.net/10261/33996
http://hdl.handle.net/10261/33996
Publikováno v:
Development (Cambridge, England). 135(19)
The Ultrabithorax (Ubx) gene of Drosophilaspecifies the third thoracic and first abdominal segments. Ubxexpression is controlled by several mechanisms, including negative regulation by its own product. We show here that if Ubx expression levels are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7445fb04aaa08fc0c61aeae9bb552c6
https://pubmed.ncbi.nlm.nih.gov/18715947
https://pubmed.ncbi.nlm.nih.gov/18715947