Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Daniel L Rock"'
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009971 (2021)
Viruses have evolved mechanisms to subvert critical cellular signaling pathways that regulate a wide range of cellular functions, including cell differentiation, proliferation and chemotaxis, and innate immune responses. Here, we describe a novel ORF
Externí odkaz:
https://doaj.org/article/42c2a4943461417a8be8a5a37aa4c811
Publikováno v:
PLoS Pathogens, Vol 13, Iss 12, p e1006779 (2017)
Poxviruses have evolved multiple strategies to subvert signaling by Nuclear Factor κB (NF-κB), a crucial regulator of host innate immune responses. Here, we describe an orf virus (ORFV) virion-associated protein, ORFV119, which inhibits NF-κB sign
Externí odkaz:
https://doaj.org/article/2a3cd1d678e6419f88093e85f85c1980
Autor:
Sushil Khatiwada, Gustavo Delhon, Ponnuraj Nagendraprabhu, Sabal Chaulagain, Shuhong Luo, Diego G Diel, Eduardo F Flores, Daniel L Rock
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006561 (2017)
Poxviruses have evolved unique proteins and mechanisms to counteract the nuclear factor κB (NF-κB) signaling pathway, which is an essential regulatory pathway of host innate immune responses. Here, we describe a NF-κB inhibitory virion protein of
Externí odkaz:
https://doaj.org/article/b1d0abe032294ef9942f4da6008c9c56
Autor:
Daxiang Chen, Zewei Zheng, Bin Xiao, Wei Li, Mingjian Long, Huiqin Chen, Ming Li, Daniel L Rock, Wenbo Hao, Shuhong Luo
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
Orf virus (ORFV), a member of Parapoxvirus, has evolved various strategies to modulate the immune responses of host cells. The ORFV-encoded protein ORFV002, a regulator factor, has been found to inhibit the acetylation of NF-κB-p65 by blocking phosp
Externí odkaz:
https://doaj.org/article/64a51ce4febf42f98c7097f7009daac6
Autor:
Xuelin eChi, Xiancheng eZeng, Wei eLi, Wenbo eHao, Ming eLi, Xiaohong eHuang, Yifan eHuang, Daniel L Rock, Shuhong eLuo, Shihua eWang
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Orf virus (ORFV), a species of the genus Parapoxvirus of the family Poxviridae, causes nonsystemic, highly contagious and eruptive disease in sheep, goat, and other wild and domestic ruminants. Our previous work shows orf to be ubiquitous in the Fuji
Externí odkaz:
https://doaj.org/article/8fe062451a684a80aa94d73145a52aff
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1009971 (2021)
PLoS Pathogens
PLoS Pathogens
Viruses have evolved mechanisms to subvert critical cellular signaling pathways that regulate a wide range of cellular functions, including cell differentiation, proliferation and chemotaxis, and innate immune responses. Here, we describe a novel ORF
Autor:
Urban Lundberg, P. Bryon Backenson, Daniel L. Rock, Christopher L. Cooper, Adriana Marques, Jean I. Tsao, Will Laegreid, Paul M. Arnaboldi, Sam R. Telford, Sukanya Narasimhan, Stanley A. Plotkin, Joppe W. Hovius, Steven E. Schutzer, X. Frank Yang, Maria Gomes-Solecki, Utpal Pal, Patricia Rosa, Joao H. F. Pedra, Maria A. Diuk-Wasser, Philip J. Molloy, Richard T. Marconi, Raymond J. Dattwyler, Jorge L. Benach, Erol Fikrig
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Lyme disease, caused by some Borrelia burgdorferi sensu lato, is the most common tick-borne illness in the Northern Hemisphere and the number of cases, and geographic spread, continue to grow. Previously identified B. burgdorferi proteins, lipid immu
Autor:
Chao Sui, Changhee Lee, Feng Li, Laura C. Miller, Dandan Jiang, Jing Qi, Sidang Liu, Daniel L. Rock, Juntong Li, Xiangju Wu, Xiaoyan Cong, Li Pan, Yijun Du, Dongwan Yoo
Publikováno v:
Journal of Virology. 95
Foot-and-mouth disease virus (FMDV) is the pathogen of foot-and-mouth disease (FMD), which is a highly contagious disease in cloven-hoofed animals. To survive in the host, FMDV has evolved multiple strategies to antagonize host innate immune response
Autor:
Daniel L. Rock
Publikováno v:
Viruses, Vol 13, Iss 943, p 943 (2021)
Viruses
Viruses
African swine fever (ASF) is an acute viral hemorrhagic disease of domestic swine with mortality rates approaching 100%. Devastating ASF outbreaks and continuing epidemics starting in the Caucasus region and now in the Russian Federation, Europe, Chi
African Swine Fever Virus CD2v protein promotes β-Interferon expression and apoptosis in swine cells
African swine fever (ASF) is a disease of swine characterized by massive lymphocyte depletion in lymphatic tissues due to apoptosis of B and T cells, most likely triggered by proteins or factors secreted by infected adjacent macrophages. Here we desc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::034b6e32971aa41651818764b3ff73f6
https://doi.org/10.1101/2020.11.06.372417
https://doi.org/10.1101/2020.11.06.372417