Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Daniel L McCartney"'
Autor:
Danni A Gadd, Robert F Hillary, Daniel L McCartney, Shaza B Zaghlool, Anna J Stevenson, Yipeng Cheng, Chloe Fawns-Ritchie, Cliff Nangle, Archie Campbell, Robin Flaig, Sarah E Harris, Rosie M Walker, Liu Shi, Elliot M Tucker-Drob, Christian Gieger, Annette Peters, Melanie Waldenberger, Johannes Graumann, Allan F McRae, Ian J Deary, David J Porteous, Caroline Hayward, Peter M Visscher, Simon R Cox, Kathryn L Evans, Andrew M McIntosh, Karsten Suhre, Riccardo E Marioni
Publikováno v:
eLife, Vol 12 (2023)
Externí odkaz:
https://doaj.org/article/49877892abd24e60be24474ec13ce578
Autor:
Robert F Hillary, Daniel L McCartney, Hannah M Smith, Elena Bernabeu, Danni A Gadd, Aleksandra D Chybowska, Yipeng Cheng, Lee Murphy, Nicola Wrobel, Archie Campbell, Rosie M Walker, Caroline Hayward, Kathryn L Evans, Andrew M McIntosh, Riccardo E Marioni
Publikováno v:
PLoS Medicine, Vol 20, Iss 7, p e1004247 (2023)
BackgroundDNA methylation is a dynamic epigenetic mechanism that occurs at cytosine-phosphate-guanine dinucleotide (CpG) sites. Epigenome-wide association studies (EWAS) investigate the strength of association between methylation at individual CpG si
Externí odkaz:
https://doaj.org/article/f0b1e6cceb97419e8873e65cb9b0489b
Autor:
Sarah Cunningham-Burley, Daniel L McCartney, Archie Campbell, Robin Flaig, Clare El Orange, Carol Porteous, Mhairi Aitken, Ciaran Mulholland, Sara Davidson, Selena M McCafferty
Publikováno v:
International Journal of Population Data Science, Vol 7, Iss 3 (2022)
Objectives There were two objectives to this study: 1) to gauge public opinion on the use of Guthrie card-derived blood samples for epidemiological and biological research; and 2) to evaluate the feasibility of recovering meaningful molecular data fr
Externí odkaz:
https://doaj.org/article/7aef3321377e45c6a33a32f90b87f40a
Autor:
Charlotte F Huggins, Alison Forbes, Anna J Stevenson, Grant Fulton, Jim Hume, Daniel L McCartney, Janet Miles, Claire Thirlwall, Caroline Hayward, Ian J Deary, Andrew M McIntosh, Riccardo E Marioni, Chloe Fawns-Ritchie, David J Porteous, Clifford Nangle, Louise Hartley, Cathie Sudlow, Christie Levein, Rebecca Dawson, Robin Flaig, Archie Campbell, Rachel Edwards
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
RuralCovidLife is part of Generation Scotland’s CovidLife project, investigating the impact of the COVID-19 pandemic and mitigation measures on people in Scotland. The RuralCovidLife project focuses on Scotland’s rural communities, and how they h
Externí odkaz:
https://doaj.org/article/17b441d0a9a6441b81d9867ee605393e
Autor:
Charlotte F Huggins, Drew M Altschul, Chloe Fawns-Ritchie, Stephanie L Sinclair, Daniel L McCartney, Dawn Haughton, Clare Dolan, Judith Brown, Judith Mabelis, Daniel J Smith, Jo Inchley, Caroline Hayward, Ian J Deary, Andrew M McIntosh, Riccardo E Marioni, David J Porteous, Clifford Nangle, Louise Hartley, Cathie Sudlow, Christie Levein, Rebecca Dawson, Robin Flaig, Archie Campbell, Rachel Edwards
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
TeenCovidLife is part of Generation Scotland’s CovidLife projects, a set of longitudinal observational studies designed to assess the psychosocial and health impacts of the COVID-19 pandemic. TeenCovidLife focused on how adolescents in Scotland wer
Externí odkaz:
https://doaj.org/article/9978fa2b34b848038b04028ef9455a7e
Autor:
Fernanda Morales Berstein, Daniel L McCartney, Ake T Lu, Konstantinos K Tsilidis, Emmanouil Bouras, Philip Haycock, Kimberley Burrows, Amanda I Phipps, Daniel D Buchanan, Iona Cheng, the PRACTICAL consortium, Richard M Martin, George Davey Smith, Caroline L Relton, Steve Horvath, Riccardo E Marioni, Tom G Richardson, Rebecca C Richmond
Publikováno v:
eLife, Vol 11 (2022)
Background: Epigenetic clocks have been associated with cancer risk in several observational studies. Nevertheless, it is unclear whether they play a causal role in cancer risk or if they act as a non-causal biomarker. Methods: We conducted a two-sam
Externí odkaz:
https://doaj.org/article/4e1402d624c84c12b18465047e355ffa
Autor:
Danni A Gadd, Robert F Hillary, Robert I McGeachan, Sarah E Harris, Daniel L McCartney, N Joan Abbott, Roy A Sherwood, Riccardo E Marioni, Simon R Cox
Publikováno v:
Wellcome Open Research, Vol 6 (2022)
Background: Circulating S100 calcium-binding protein (S100β) is a marker of brain inflammation that has been associated with a range of neurological conditions. To provide insight into the molecular regulation of S100β and its potential causal asso
Externí odkaz:
https://doaj.org/article/aba8554a710746e786e0ab5bcd2d66ec
Autor:
Danni A Gadd, Robert F Hillary, Daniel L McCartney, Shaza B Zaghlool, Anna J Stevenson, Yipeng Cheng, Chloe Fawns-Ritchie, Cliff Nangle, Archie Campbell, Robin Flaig, Sarah E Harris, Rosie M Walker, Liu Shi, Elliot M Tucker-Drob, Christian Gieger, Annette Peters, Melanie Waldenberger, Johannes Graumann, Allan F McRae, Ian J Deary, David J Porteous, Caroline Hayward, Peter M Visscher, Simon R Cox, Kathryn L Evans, Andrew M McIntosh, Karsten Suhre, Riccardo E Marioni
Publikováno v:
eLife, Vol 11 (2022)
Protein biomarkers have been identified across many age-related morbidities. However, characterising epigenetic influences could further inform disease predictions. Here, we leverage epigenome-wide data to study links between the DNA methylation (DNA
Externí odkaz:
https://doaj.org/article/97b5228535ef4e2596046a3a97ea7f67
Autor:
Danni A Gadd, Robert F Hillary, Robert I McGeachan, Sarah E Harris, Daniel L McCartney, N Joan Abbott, Roy A Sherwood, Riccardo E Marioni, Simon R Cox
Publikováno v:
Wellcome Open Research, Vol 6 (2021)
Background: Circulating S100 calcium-binding protein (S100β) is a marker of brain inflammation that has been associated with a range of neurological conditions. To provide insight into the molecular regulation of S100β and its potential causal asso
Externí odkaz:
https://doaj.org/article/47dd8428cea1470e8f25fd8c9a58b659
Autor:
Julie Hahn, Jan Bressler, Arce Domingo-Relloso, Ming-Huei Chen, Daniel L. McCartney, Alexander Teumer, Jenny van Dongen, Marcus E. Kleber, Dylan Aïssi, Brenton R. Swenson, Jie Yao, Wei Zhao, Jian Huang, Yujing Xia, Michael R. Brown, Ricardo Costeira, Eco J.C. de Geus, Graciela E. Delgado, Dre'Von A. Dobson, Paul Elliott, Hans J. Grabe, Xiuqing Guo, Sarah E. Harris, Jennifer E. Huffman, Sharon L.R. Kardia, Yongmei Liu, Stefan Lorkowski, Riccardo E. Marioni, Matthias Nauck, Scott M. Ratliff, Maria Sabater-Lleal, Tim D. Spector, Pierre Suchon, Kent D. Taylor, Florian Thibord, David-Alexandre Trégouët, Kerri L. Wiggins, Gonneke Willemsen, Jordana T. Bell, Dorret I. Boomsma, Shelley A. Cole, Simon R. Cox, Abbas Dehghan, Andreas Greinacher, Karin Haack, Winfried März, Pierre-Emmanuel Morange, Jerome I. Rotter, Nona Sotoodehnia, Maria Tellez-Plaza, Ana Navas-Acien, Jennifer A. Smith, Andrew D. Johnson, Myriam Fornage, Nicholas L. Smith, Alisa S. Wolberg, Alanna C. Morrison, Paul S. de Vries
Publikováno v:
Hahn, J, Bressler, J, Domingo-Relloso, A, Chen, M H, McCartney, D L, Teumer, A, van Dongen, J, Kleber, M E, Aïssi, D, Swenson, B R, Yao, J, Zhao, W, Huang, J, Xia, Y, Brown, M R, Costeira, R, de Geus, E J C, Delgado, G E, Dobson, DV A, Elliott, P, Grabe, H J, Guo, X, Harris, S E, Huffman, J E, Kardia, S L R, Liu, Y, Lorkowski, S, Marioni, R E, Nauck, M, Ratliff, S M, Sabater-Lleal, M, Spector, T D, Suchon, P, Taylor, K D, Thibord, F, Trégouët, D A, Wiggins, K L, Willemsen, G, Bell, J T, Boomsma, D I, Cole, S A, Cox, S R, Dehghan, A, Greinacher, A, Haack, K, März, W, Morange, P E, Rotter, J I, Sotoodehnia, N, Tellez-Plaza, M, Navas-Acien, A, Smith, J A, Johnson, A D, Fornage, M, Smith, N L, Wolberg, A S, Morrison, A C & de Vries, P S 2023, ' DNA methylation analysis is used to identify novel genetic loci associated with circulating fibrinogen levels in blood ', Journal of Thrombosis and Haemostasis, vol. 21, no. 5, pp. 1135-1147 . https://doi.org/10.1016/j.jtha.2023.01.015
Journal of Thrombosis and Haemostasis, 21(5), 1135-1147. Wiley-Blackwell
Journal of thrombosis and haemostasis 21(5), 1135-1147 (2023). doi:10.1016/j.jtha.2023.01.015
Journal of Thrombosis and Haemostasis, 21(5), 1135-1147. Wiley-Blackwell
Journal of thrombosis and haemostasis 21(5), 1135-1147 (2023). doi:10.1016/j.jtha.2023.01.015
Background: Fibrinogen plays an essential role in blood coagulation and inflammation. Circulating fibrinogen levels may be determined based on interindividual differences in DNA methylation at cytosine-phosphate-guanine (CpG) sites and vice versa. Ob