Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Daniel L Lakeland"'
Publikováno v:
eLife, Vol 6 (2017)
For decades, the mechanism of skeletal patterning along a proximal-distal axis has been an area of intense inquiry. Here, we examine the development of the ribs, simple structures that in most terrestrial vertebrates consist of two skeletal elements
Externí odkaz:
https://doaj.org/article/ea693fa510df43adbdd0b9c591c8ff15
Autor:
Dennis J Hazelett, Suhn Kyong Rhie, Malaina Gaddis, Chunli Yan, Daniel L Lakeland, Simon G Coetzee, Ellipse/GAME-ON consortium, Practical consortium, Brian E Henderson, Houtan Noushmehr, Wendy Cozen, Zsofia Kote-Jarai, Rosalind A Eeles, Douglas F Easton, Christopher A Haiman, Wange Lu, Peggy J Farnham, Gerhard A Coetzee
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004102 (2014)
Genome-wide association studies (GWAS) have revolutionized the field of cancer genetics, but the causal links between increased genetic risk and onset/progression of disease processes remain to be identified. Here we report the first step in such an
Externí odkaz:
https://doaj.org/article/3a59b327630346c79a8646ea0eb44590
Publikováno v:
Journal of NeuroEngineering and Rehabilitation. 19
Background Musculoskeletal modeling is currently a preferred method for estimating the muscle forces that underlie observed movements. However, these estimates are sensitive to a variety of assumptions and uncertainties, which creates difficulty when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830443b978eb47b61b90075b0e5b896d
https://doi.org/10.1186/s12984-022-01008-4
https://doi.org/10.1186/s12984-022-01008-4
Publikováno v:
iScience
iScience, Vol 24, Iss 10, Pp 103084-(2021)
iScience, Vol 24, Iss 10, Pp 103084-(2021)
Summary Cancer is an organism-level disease, impacting processes from cellular metabolism and the microenvironment to systemic immune response. Nevertheless, efforts to distinguish overarching mutational processes from interactions with the cell of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f9db80c2503769a1ff2c92b4d395e49
http://europepmc.org/articles/PMC8477189
http://europepmc.org/articles/PMC8477189
Autor:
Rachel Soloff, Charles Wang, Daniel L. Lakeland, Francesca V. Mariani, In Kyoung Mah, Audrey K. Izuhara
Publikováno v:
Dev Biol
Polarized epithelia define boundaries, spaces, and cavities within organisms. Cavitation, a process by which multicellular hollow balls or tubes are produced, is typically associated with the formation of organized epithelia. In order for these epith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8538b95310ae964bfb0cea96df56d28d
https://doi.org/10.1016/j.ydbio.2016.06.002
https://doi.org/10.1016/j.ydbio.2016.06.002
Publikováno v:
G3: Genes|Genomes|Genetics
The human Tar-DNA binding protein, TDP-43, is associated with amyotrophic lateral sclerosis (ALS) and other neurodegenerative disorders. TDP-43 contains two conserved RNA-binding motifs and has documented roles in RNA metabolism, including pre-mRNA s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63b1e7c0581608d9741104b2ffe6ec8
http://europepmc.org/articles/PMC3385985
http://europepmc.org/articles/PMC3385985
Publikováno v:
Bioinformatics
Methods: A new method was developed for identifying novel transcription factor regulatory targets based on calculating Local Affinity Density. Techniques from the signal-processing field were used, in particular the Hann digital filter, to calculate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55fb5d66d3818ec25dd14e16773f2cf9
https://doi.org/10.1093/bioinformatics/btp282
https://doi.org/10.1093/bioinformatics/btp282
Autor:
Marissa K, Srour, Jennifer L, Fogel, Kent T, Yamaguchi, Aaron P, Montgomery, Audrey K, Izuhara, Aaron L, Misakian, Stephanie, Lam, Daniel L, Lakeland, Mark M, Urata, Janice S, Lee, Francesca V, Mariani
Publikováno v:
J Bone Miner Res
The clinical need for methods to repair and regenerate large cartilage and bone lesions persists. One way to make new headway is to study skeletal regeneration when it occurs naturally. Cartilage repair is typically slow and incomplete. However, an e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba191a3b81dbcce587139679dc840fd0
https://pubmed.ncbi.nlm.nih.gov/25142306
https://pubmed.ncbi.nlm.nih.gov/25142306
Autor:
Dennis J Hazelett, Suhn Kyong Rhie, Malaina Gaddis, Chunli Yan, Daniel L Lakeland, Simon G Coetzee, Ellipse/GAME-ON consortium, Practical consortium, Brian E Henderson, Houtan Noushmehr, Wendy Cozen, Zsofia Kote-Jarai, Rosalind A Eeles, Douglas F Easton, Christopher A Haiman, Wange Lu, Peggy J Farnham, Gerhard A Coetzee
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 10, Iss 1, p e1004102 (2014)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS Genetics, Vol 10, Iss 1, p e1004102 (2014)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Genome-wide association studies (GWAS) have revolutionized the field of cancer genetics, but the causal links between increased genetic risk and onset/progression of disease processes remain to be identified. Here we report the first step in such an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5fc8e9afe9888213000e949cdd08840
https://pubmed.ncbi.nlm.nih.gov/24497837
https://pubmed.ncbi.nlm.nih.gov/24497837