Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Daniel L Jacoby"'
Autor:
Caroline J. Coats, Ahmad Masri, Michael E. Nassif, Roberto Barriales‐Villa, Michael Arad, Nuno Cardim, Lubna Choudhury, Brian Claggett, Hans‐Dirk Düngen, Pablo Garcia‐Pavia, Albert A. Hagège, James L. Januzzi, Matthew M. Y. Lee, Gregory D. Lewis, Chang‐Sheng Ma, Martin S. Maron, Zi Michael Miao, Michelle Michels, Iacopo Olivotto, Artur Oreziak, Anjali T. Owens, John A. Spertus, Scott D. Solomon, Jacob Tfelt‐Hansen, Marion van Sinttruije, Josef Veselka, Hugh Watkins, Daniel L. Jacoby, Polina German, Stephen B. Heitner, Stuart Kupfer, Justin D. Lutz, Fady I. Malik, Lisa Meng, Amy Wohltman, Theodore P. Abraham
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Aficamten, a novel cardiac myosin inhibitor, reversibly reduces cardiac hypercontractility in obstructive hypertrophic cardiomyopathy. We present a prespecified analysis of the pharmacokinetics, pharmacodynamics, and safety of aficamten in
Externí odkaz:
https://doaj.org/article/ecd7f5b3949f4a8ca276c42cd7292a3f
Autor:
Veer Sangha, Bobak J. Mortazavi, Adrian D. Haimovich, Antônio H. Ribeiro, Cynthia A. Brandt, Daniel L. Jacoby, Wade L. Schulz, Harlan M. Krumholz, Antonio Luiz P. Ribeiro, Rohan Khera
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The application of artificial intelligence for automated diagnosis of electrocardiograms can improve care in remote settings but is limited by the reliance on infrequently available signal-based data. Here, the authors report the development of a mul
Externí odkaz:
https://doaj.org/article/88e86de62c67471e97b250d7db5e1ce7
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 12 (2021)
Externí odkaz:
https://doaj.org/article/f9193ec5b2a848cfa566e25398772edc
Autor:
Lorenzo R. Sewanan, MS, Jonas Schwan, PhD, Jonathan Kluger, BSE, Jinkyu Park, PhD, Daniel L. Jacoby, MD, Yibing Qyang, PhD, Stuart G. Campbell, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 4, Pp 495-505 (2019)
Summary: Hypertrophic cardiomyopathy (HCM) is often caused by single sarcomeric gene mutations that affect muscle contraction. Pharmacological correction of mutation effects prevents but does not reverse disease in mouse models. Suspecting that disea
Externí odkaz:
https://doaj.org/article/aeb99494d02840d79b8504d6e2152e7a
Autor:
Angela Y. Higgins, Amarnath R. Annapureddy, Yongfei Wang, Karl E. Minges, Rachel Lampert, Lynda E. Rosenfeld, Daniel L. Jacoby, Jeptha P. Curtis, Edward J. Miller, James V. Freeman
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 18 (2020)
Background Outcomes data in patients with cardiac amyloidosis after implantable cardioverter‐defibrillator (ICD) implantation are limited. We compared outcomes of patients with ICDs implanted for cardiac amyloidosis versus nonischemic cardiomyopath
Externí odkaz:
https://doaj.org/article/637f1729405f49278d7307ee26dded1d
Autor:
Allison E. Gaffey, Kristie M. Harris, Carlos Mena-Hurtado, Rajita Sinha, Daniel L. Jacoby, Kim G. Smolderen
Publikováno v:
Health Psychology. 41:779-791
Cardiovascular disease remains the leading cause of morbidity and mortality in industrialized nations. Many patients living with chronic cardiovascular disease suffer from complex multimorbidities requiring high-intensity care and behavioral risk fac
Autor:
Stephen, Breazeale, Sangchoon, Jeon, Youri, Hwang, Meghan, O'Connell, Uzoji, Nwanaji-Enwerem, Sarah, Linsky, H Klar, Yaggi, Daniel L, Jacoby, Samantha, Conley, Nancy S, Redeker
Publikováno v:
Nurs Res
Almost 50% of people with heart failure (HF) experience chronic insomnia and must perform self-care to manage their day-to-day healthcare needs. Understanding multifactorial influences on self-care, including demographic, clinical, and sleep characte
Autor:
Muhammad Riaz, Jinkyu Park, Lorenzo R. Sewanan, Yongming Ren, Jonas Schwan, Subhash K. Das, Pawel T. Pomianowski, Yan Huang, Matthew W. Ellis, Jiesi Luo, Juli Liu, Loujin Song, I-Ping Chen, Caihong Qiu, Masayuki Yazawa, George Tellides, John Hwa, Lawrence H. Young, Lei Yang, Charles C. Marboe, Daniel L. Jacoby, Stuart G. Campbell, Yibing Qyang
Publikováno v:
Circulation
Background: Familial hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease and is typically caused by mutations in genes encoding sarcomeric proteins that regulate cardiac contractility. HCM manifestations include left ventri
Autor:
Angela Y. Higgins, Amarnath R. Annapureddy, Yongfei Wang, Karl E. Minges, Lavanya Bellumkonda, Rachel Lampert, Lynda E. Rosenfeld, Daniel L. Jacoby, Jeptha P. Curtis, Edward J. Miller, James V. Freeman
Publikováno v:
American Heart Journal. 246:21-31
Implantable cardioverter-defibrillators (ICDs) are recommended for patients with cardiac sarcoidosis (CS) with an indication for pacing, prior ventricular arrhythmias, cardiac arrest, or left ventricular ejection fraction35%, but data on outcomes are
Autor:
Eric Smith, Brynn Elder, Gabriela Chen, Yao-chang Tsan, John Stendahl, Jodie Ingles, Victoria N Parikh, Samuel Wittekind, Steven Colan, Neal K Lakdawala, Anjali T Owens, Daniel L Jacoby, Sharlene Day, Christopher Semsarian, iacopo olivotto, Carolyn Ho, Mark W Russell, Sara Saberi, James S Ware, Adam S Helms
Publikováno v:
Circulation. 144
Introduction: Genetic hypertrophic cardiomyopathy (HCM) is an autosomal dominant inherited condition primarily due to pathogenic variants in sarcomere genes, often with marked clinical variability. We hypothesized that this variability may, in part,