Zobrazeno 1 - 10 of 48 pro vyhledávání: '"Daniel L Halligan"'
1
Akademický článek
Contributions of protein-coding and regulatory change to adaptive molecular evolution in murid rodents.
Autor: Daniel L Halligan, Athanasios Kousathanas, Rob W Ness, Bettina Harr, Lél Eöry, Thomas M Keane, David J Adams, Peter D Keightley
Publikováno v: PLoS Genetics, Vol 9, Iss 12, p e1003995 (2013)
The contribution of regulatory versus protein change to adaptive evolution has long been controversial. In principle, the rate and strength of adaptation within functional genetic elements can be quantified on the basis of an excess of nucleotide sub
Externí odkaz: https://doaj.org/article/e5c9a33f7be8443caf7eeda4621c9fbf
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2
Akademický článek
Evidence for pervasive adaptive protein evolution in wild mice.
Autor: Daniel L Halligan, Fiona Oliver, Adam Eyre-Walker, Bettina Harr, Peter D Keightley
Publikováno v: PLoS Genetics, Vol 6, Iss 1, p e1000825 (2010)
The relative contributions of neutral and adaptive substitutions to molecular evolution has been one of the most controversial issues in evolutionary biology for more than 40 years. The analysis of within-species nucleotide polymorphism and between-s
Externí odkaz: https://doaj.org/article/c01809c286fe4c8bb493c05fdccee3cd
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6
Data from Comprehensive Profiling of Poor-Risk Paired Primary and Recurrent Triple-Negative Breast Cancers Reveals Immune Phenotype Shifts
Autor: Yuan Yuan, Jackson Liang, Daniel Schmolze, Chun-Chieh Chang, Daniel L. Halligan, Paul R. McAdam, Adrian R. Carr, Radia Marie Johnson, Ching-Wei Chang, Susan E. Yost, Katherine E. Hutchinson
Purpose:Emerging data suggest immune checkpoint inhibitors have reduced efficacy in heavily pretreated triple-negative breast cancers (TNBC), but underlying mechanisms are poorly understood. To better understand the phenotypic evolution of TNBCs, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c787f547309f463581297cbc8365dd
https://doi.org/10.1158/1078-0432.c.6528353
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9
Comprehensive Profiling of Poor-Risk Paired Primary and Recurrent Triple-Negative Breast Cancers Reveals Immune Phenotype Shifts
Autor: Yuan Yuan, Radia M. Johnson, Daniel Schmolze, Katherine E. Hutchinson, Adrian R. Carr, Daniel L. Halligan, Ching-Wei Chang, Paul R. McAdam, Susan E. Yost, Jackson Liang, Chun-Chieh Chang
Publikováno v: Clin Cancer Res
Purpose: Emerging data suggest immune checkpoint inhibitors have reduced efficacy in heavily pretreated triple-negative breast cancers (TNBC), but underlying mechanisms are poorly understood. To better understand the phenotypic evolution of TNBCs, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45745827bfb4951888cf41e5280d9ca
https://doi.org/10.1158/1078-0432.ccr-19-1773
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10
Gene expression profiling of placentae from women with obesity and obstructive sleep apnoea
Autor: Emma C. Johns, Daniel L. Halligan, Triin Tammsalu, Elizabeth A. Hill, Renata L. Riha, Fiona C. Denison, Rebecca M. Reynolds
Publikováno v: Johnson, E C, Halligan, D, Tammsalu, T, Hill, E A, Riha, R L, Denison, F C & Reynolds, R M 2022, ' Gene expression profiling of placentae from women with obesity and obstructive sleep apnoea ', Placenta . https://doi.org/10.1016/j.placenta.2022.03.001
Introduction: Obstructive sleep apnoea (OSA), a condition characterised by intermittent hypoxia and reoxygenation during sleep, is associated with an increased risk of adverse pregnancy outcomes including gestational diabetes and hypertensive disorde
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4864c9c08f21eca173c4d1ef973a97
https://pubmed.ncbi.nlm.nih.gov/35278842
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