Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Daniel L Chase"'
Autor:
Khursheed A Wani, Mary Catanese, Robyn Normantowicz, Muriel Herd, Kathryn N Maher, Daniel L Chase
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e37831 (2012)
Dopamine signaling modulates voluntary movement and reward-driven behaviors by acting through G protein-coupled receptors in striatal neurons, and defects in dopamine signaling underlie Parkinson's disease and drug addiction. Despite the importance o
Externí odkaz:
https://doaj.org/article/2a061ed844834c29851714be6bd18def
Autor:
Tom Sanders, Michael N. Nitabach, Li Yan McCurdy, Netta Cohen, Daniel L. Chase, D. Dipon Ghosh, Soonwook Hong, Michael R. Koelle
Publikováno v:
Neuron. 92:1049-1062
Little is known about how animals integrate multiple sensory inputs in natural environments to balance avoidance of danger with approach to things of value. Furthermore, the mechanistic link between internal physiological state and threat-reward deci
Publikováno v:
Genetics. 188:579-590
Dopamine acts through two classes of G protein-coupled receptor (D1-like and D2-like) to modulate neuron activity in the brain. While subtypes of D1- and D2-like receptors are coexpressed in many neurons of the mammalian brain, it is unclear how sign
Autor:
Daniel L. Chase
Publikováno v:
Teaching Lifetime Outdoor Pursuits. :17-32
Publikováno v:
Genes & Development. 14:2003-2014
Regulators of G protein signaling (RGS proteins) inhibit heterotrimeric G protein signaling by activating G protein GTPase activity. Many mammalian RGS proteins are expressed in the brain and can act in vitro on the neural G protein Go, but the biolo
Autor:
Andy Golden, Douglas K. Ferris, Dan L. Longo, Christina Serafinas, Daniel L. Chase, Mary E. Kosinski, Neville R. Ashcroft
Publikováno v:
genesis. 26:26-41
Summary: The Polo-like kinases are key regulatory molecules required during the cell cycle for the successful completion of mitosis. We have cloned a C. elegans homolog of the Drosophila melanogaster polo gene (designated plk-1 for C. elegans polo-li
Publikováno v:
DNA Sequence. 11:327-334
The Polo family of serine/threonine kinases have been implicated in cell cycle control in a number of diverse organisms. Their localization and biochemical activity suggest that they play an important role in centro-some maturation, G2—to-M phase p
Autor:
Daniel L. Chase, Yang Feng, David R. Hodge, Douglas K. Ferris, Giuseppe Palmieri, Dan L. Longo
Publikováno v:
Biochemical Journal. 339:435-442
The polo-like kinase (Plk) family has been shown to have an important role in the regulation of the cell-division cycle, especially in organization of the spindle structure, in species from fungi to humans. Recent reports have demonstrated that in ma
Autor:
Ryoji Hamanaka, Dan L. Longo, Hsiang-Fu Kung, Douglas K. Ferris, Mark R. Smith, Daniel L. Chase, Michael L. Wilson
Publikováno v:
Biochemical and Biophysical Research Communications. 234:397-405
Polo-like kinase (Plk) is the mammalian homologue of the Drosophila polo and Saccharomyces cerevisiae CDC5 genes, which are thought to be involved in regulating chromosomal segregation. Previously, we showed that transient ectopic expression of Plk c
Publikováno v:
Journal of visualized experiments : JoVE. (79)
RNA interference by feeding worms bacteria expressing dsRNAs has been a useful tool to assess gene function in C. elegans. While this strategy works well when a small number of genes are targeted for knockdown, large scale feeding screens show variab