Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniel Krys"'
Publikováno v:
Molecular Imaging and Biology. 22:1562-1571
The present study describes the analysis of amino acid transporters ASCT1, ASCT2, LAT1, and xc− in breast cancer under normoxic and hypoxic conditions. [18F]FDOPA-PET and [18F]FSPG-PET were used as imaging biomarkers to probe l-type amino acid tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::990007e32242296ae5ade8b6b671d4ff
https://doi.org/10.1007/s11307-020-01529-1
https://doi.org/10.1007/s11307-020-01529-1
Publikováno v:
The FASEB Journal. 33:13837-13851
Elevated proliferation rates in cancer can be visualized with positron emission tomography (PET) using 3′-deoxy-3′-l-[18F]fluorothymidine ([18F]FLT). This study investigates whether [18F]FLT transp...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a35acfd0e817c13d6bb3082d43e4ba
https://doi.org/10.1096/fj.201900870rr
https://doi.org/10.1096/fj.201900870rr
Autor:
Simon, Ferguson, Melinda, Wuest, Susan, Richter, Cody, Bergman, Jennifer, Dufour, Daniel, Krys, Jennifer, Simone, Hans-Sonke, Jans, Terence, Riauka, Frank, Wuest
Publikováno v:
Nuclear medicine and biology.
Radiolabeled peptides play a central role in nuclear medicine as radiotheranostics for targeted imaging and therapy of cancer. We have recently proposed the use of metabolically stabilized GRPR antagonist BBN2 for radiolabeling withDOTA-Ava-BBN2 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7cab5b1615b4e3087420da83b0b80d0a
https://pubmed.ncbi.nlm.nih.gov/33189947
https://pubmed.ncbi.nlm.nih.gov/33189947
Publikováno v:
Molecular imaging and biology. 22(6)
The present study describes the analysis of amino acid transporters ASCT1, ASCT2, LAT1, and xLAT1 and xASCT1 protein expression levels were comparable in all three cell lines, while noticeable ASCT2 expression levels were only found in MCF10A control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c0fe64f6bf5bd22bf7a233ed7de1090b
https://pubmed.ncbi.nlm.nih.gov/32789819
https://pubmed.ncbi.nlm.nih.gov/32789819
Autor:
Frank Wuest, Darryl D. Glubrecht, Daniel Krys, Vincent Bouvet, Melinda Wuest, Larissa J. Vos, Alison Marshall, John R. Mackey, Ingrit Hamann
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32(9)
Elevated growth in breast cancer (BC) activates hypoxia-inducible factor (HIF1α) and downstream, facilitative glucose transporter 1 (GLUT1), which can be visualized with 2-deoxy-2-[18F]fluoro-d-glucose ([18F]FDG). GLUT5 (fructose) and GLUT2 (glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb22b76bd95c6cd3dae99da4b02985a
https://pubmed.ncbi.nlm.nih.gov/29913554
https://pubmed.ncbi.nlm.nih.gov/29913554
Autor:
Vincent Bouvet, Frederick G. West, Ingrit Hamann, Michael Wagner, Olivier-Mohamad Soueidan, Chris I. Cheeseman, Alison Marshall, Daniel Krys, Brendan J. Trayner, Darryl D. Glubrecht, Melinda Wuest, Frank Wuest
Publikováno v:
Molecular pharmacology. 93(2)
Use of [18F]FDG-positron emission tomography (PET) in clinical breast cancer (BC) imaging is limited mainly by insufficient expression levels of facilitative glucose transporter (GLUT)1 in up to 50% of all patients. Fructose-specific facilitative hex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9fb6d3b81a20ce7e2e754f8f2ffc460
https://pubmed.ncbi.nlm.nih.gov/29142019
https://pubmed.ncbi.nlm.nih.gov/29142019