Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Daniel Kortzak"'
Autor:
Bettina Kolen, Bart Borghans, Daniel Kortzak, Victor Lugo, Cora Hannack, Raul E. Guzman, Ghanim Ullah, Christoph Fahlke
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Vesicular glutamate transporters accumulate glutamate in synaptic vesicles, where they also function as a major Cl- efflux pathway. Here we combine heterologous expression and cellular electrophysiology with mathematical modeling to understa
Externí odkaz:
https://doaj.org/article/d23f45dcf0ea4ebfa5e44b1ac9fca332
Publikováno v:
Bio-Protocol, Vol 13, Iss 13 (2023)
Determining the oligomeric state of membrane proteins is critical for understanding their function. However, traditional ex situ methods like clear native gel electrophoresis can disrupt protein subunit interactions during sample preparation. In situ
Externí odkaz:
https://doaj.org/article/681f33bbc1c448c880286a5828836d39
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
SLC1A2 and SLC1A3 encode the glial glutamate transporters EAAT2 and EAAT1, which are not only the predominant glutamate uptake carriers in our brain, but also function as anion channels. Two homologous mutations, which predict substitutions of prolin
Externí odkaz:
https://doaj.org/article/f58c2c9fcc4f4e0fab8413c374796c16
Autor:
Hua Leonhard Tan, Stefanie Bungert-Plümke, Daniel Kortzak, Christoph Fahlke, Gabriel Stölting
Publikováno v:
eLife, Vol 11 (2022)
The oligomeric state of plasma membrane proteins is the result of the interactions between individual subunits and an important determinant of their function. Most approaches used to address this question rely on extracting these complexes from their
Externí odkaz:
https://doaj.org/article/fc4dc5abe8464c1995514559c5a53c84
Autor:
Rachel Conrad, Gabriel Stölting, Johnny Hendriks, Giovanna Ruello, Daniel Kortzak, Nadine Jordan, Thomas Gensch, Patricia Hidalgo
Publikováno v:
iScience, Vol 7, Iss , Pp 1-15 (2018)
Summary: Calcium entry through CaV1.2 L-type calcium channels regulates cardiac contractility. Here, we study the impact of exocytic and post-endocytic trafficking on cell surface channel abundance in cardiomyocytes. Single-molecule localization and
Externí odkaz:
https://doaj.org/article/8e62f39c22284d39840dc4888e99ca71
Autor:
Peter Kovermann, Margarita Hessel, Daniel Kortzak, Joanna C. Jen, Johannes Koch, Christoph Fahlke, Tobias Freilinger
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract SLC1A3 encodes the glial glutamate transporter hEAAT1, which removes glutamate from the synaptic cleft via stoichiometrically coupled Na+-K+-H+-glutamate transport. In a young man with migraine with aura including hemiplegia, we identified a
Externí odkaz:
https://doaj.org/article/29823721443a4019960ff51246f63d0e
Publikováno v:
Traffic. 22:180-193
Membrane depolarization activates the multisubunit CaV 1.2 L-type calcium channel initiating various excitation coupling responses. Intracellular trafficking into and out of the plasma membrane regulates the channel's surface expression and stability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3f53ba5e7e0afe96470ebd071c159d9
https://doi.org/10.1111/tra.12788
https://doi.org/10.1111/tra.12788
Publikováno v:
Neurochemical research 47, 9-22 (2022). doi:10.1007/s11064-021-03252-x
Neurochemical Research
Neurochemical research 47(1), 9-22 (2022). doi:10.1007/s11064-021-03252-x special issue: "Special Issue in Honor of Baruch Kanner"
Neurochemical Research
Neurochemical research 47(1), 9-22 (2022). doi:10.1007/s11064-021-03252-x special issue: "Special Issue in Honor of Baruch Kanner"
Neurochemical research 47(1), 9-22 (2022). doi:10.1007/s11064-021-03252-x special issue: "Special Issue in Honor of Baruch Kanner"
Published by Springer Science + Business Media B.V, Dordrecht [u.a.]
Published by Springer Science + Business Media B.V, Dordrecht [u.a.]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152813e6135fb7ae22e5297941751450
Autor:
Daniel Kortzak, Hua Leonhard Tan, Christoph Fahlke, Gabriel Stölting, Stefanie Bungert-Plümke
The oligomeric state of plasma membrane proteins is the result of the interactions between individual proteins and an important determinant of their function. Most approaches used to address this question rely on extracting these complexes from their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce5791e3add62481c1ebbed7f28c45ee
https://doi.org/10.1101/2021.10.05.463155
https://doi.org/10.1101/2021.10.05.463155