Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Daniel Kess"'
Autor:
Thorsten Peters, Wilhelm Bloch, Oliver Pabst, Claudia Wickenhauser, Claudia Uthoff-Hachenberg, Susanne V. Schmidt, Georg Varga, Stephan Grabbe, Daniel Kess, Tsvetelina Oreshkova, Anca Sindrilaru, Klaus Addicks, Reinhold Förster, Werner Müller, Karin Scharffetter-Kochanek
Publikováno v:
Clinical and Developmental Immunology, Vol 2012 (2012)
Absence of β2 integrins (CD11/CD18) leads to leukocyte-adhesion deficiency-1 (LAD1), a rare primary immunodeficiency syndrome. Although extensive in vitro work has established an essential function of β2 integrins in adhesive and signaling properti
Externí odkaz:
https://doaj.org/article/dd47ef933310461dbbef994d266f1f9d
Autor:
Anca Sindrilaru, Karin Scharffetter-Kochanek, Daniel Kess, Julia von Rohrscheidt, Klaus T. Preissner, Thorsten Peters, Jan Roehrbein, Honglin Wang
Publikováno v:
Journal of Investigative Dermatology. 130(3):743-754
Psoriasis is a T-cell-mediated inflammatory disease. Previous studies focused on lymphocyte function-associated antigen 1 (LFA-1)-expressing T cells as a molecular target for therapeutic intervention. By contrast, information on therapeutic effects a
Autor:
Tatiana Syrovets, Karin Scharffetter-Kochanek, Daniel Kess, Oleg Lunov, Heidi Hainzl, Johannes M. Weiss, Berthold Büchele, Honglin Wang, Thomas Simmet
Publikováno v:
The Journal of Immunology. 183:4755-4763
Psoriasis vulgaris is a common chronic inflammatory skin disease involving cytokines and an activated cellular immune system. At variance to skin from patients with atopic dermatitis or from healthy subjects, human psoriatic skin lesions exhibit stro
Autor:
Anca Sindrilaru, Daniel Kess, Honglin Wang, Anne M. Seier, Heike A. Schreiber, Jan Röhrbein, Thorsten Peters, Johannes M. Weiss, Meinhard Wlaschek, Karin Scharffetter-Kochanek, Tsvetelina Oreshkova, Guido Schulz, Robert Blakytny, Xue-Zhong Yu
Publikováno v:
Journal of Clinical Investigation. 118:2629-2639
Dysfunctional Tregs have been identified in individuals with psoriasis. However, their role in the pathogenesis of the disease remains unclear. Here we explored the effect of diminished CD18 (beta2 integrin) expression on the function of CD4+CD25+CD1
Autor:
Tsvetelina Oreshkova, Meinhard Wlaschek, Katrin Holzwarth, Ezz Al Din Al-Azzeh, Barbara Walzog, Boris Hinz, Daniel Kess, Thomas Krieg, Anca Sindrilaru, R. Hinrichs, Wilhelm Friedrich, Cord Sunderkötter, Karin Scharffetter-Kochanek, Thorsten Peters, Silke Sulyok, Honglin Wang, Andre Menke
Publikováno v:
The EMBO Journal. 24:3400-3410
We studied the mechanisms underlying the severely impaired wound healing associated with human leukocyte-adhesion deficiency syndrome-1 (LAD1) using a murine disease model. In CD18(-/-) mice, healing of full-thickness wounds was severely delayed duri
Autor:
Thorsten Peters, Thomas Krieg, Pierre Shephard, Neil Smyth, Angela Schippers, Daniel Kess, Arianna Nenci, Hans Smola, Olaf Holtkötter, Jeffrey E. Kudlow, Jutta Wenk, Manolis Pasparakis, Martin Hafner, Werner Müller, Karin Scharffetter-Kochanek, Ingo Haase
Publikováno v:
genesis. 38:176-181
Three mouse lines expressing Cre recombinase under the control of the human K14 promoter induced specific deletion of loxP flanked target sequences in the epidermis, in tongue, and thymic epithelium of the offspring where the Cre allele was inherited
Autor:
Wilhelm Bloch, Tsvetelina Oreshkova, Klaus Addicks, Daniel Kess, Stephan Grabbe, Reinhold Förster, Thorsten Peters, Oliver Pabst, Claudia Uthoff-Hachenberg, Karin Scharffetter-Kochanek, Susanne Schmidt, Claudia Wickenhauser, Werner Müller, Georg Varga, Anca Sindrilaru
Publikováno v:
Clinical and Developmental Immunology, Vol 2012 (2012)
BASE-Bielefeld Academic Search Engine
Clinical and Developmental Immunology
BASE-Bielefeld Academic Search Engine
Clinical and Developmental Immunology
Absence ofβ2integrins (CD11/CD18) leads to leukocyte-adhesion deficiency-1 (LAD1), a rare primary immunodeficiency syndrome. Although extensivein vitrowork has established an essential function ofβ2integrins in adhesive and signaling properties for
Autor:
Rikard Holmdahl, Thorsten Peters, Meinhard Wlaschek, Daniel Kess, Anca Sindrilaru, Robert Blakytny, Anna-Karin B. Lindqvist, Honglin Wang, Karin Scharffetter-Kochanek
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 180(8)
Psoriasis is a complex genetic disease of unresolved pathogenesis with both heritable and environmental factors contributing to onset and severity. In addition to a disfiguring skin inflammation, approximately 10–40% of psoriasis patients suffer fr
Autor:
Roswitha Nischt, Karl W. Broman, Jan Zamek, Thorsten Peters, Rikard Holmdahl, Karin Scharffetter-Kochanek, Thomas Krieg, Robert Blakytny, Honglin Wang, Anna-Karin B. Lindqvist, Daniel Kess
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 177(7)
Psoriasis is a frequently occurring inflammatory skin disease characterized by thickened erythematous skin that is covered with silvery scales. It is a complex genetic disease with both heritable and environmental factors contributing to onset and se
Autor:
Nico van Rooijen, Athanasios Stratis, Daniel Kess, Karin Scharffetter-Kochanek, Thorsten Peters, Anca Sindrilaru, Andreas C. Renkl, Cord Sunderkötter, Meinhard Wlaschek, Honglin Wang, Ingo Haase, Tsvetelina Oreshkova
The CD18 hypomorphic (CD18hypo) PL/J mouse model clinically resembling human psoriasis is characterized by reduced expression of the common chain of beta2 integrins (CD11/CD18) to only 2-16% of WT levels. Previously we found that this chronic psorias
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7044f50b53ee3d395064e3bdefe2a0fa
https://europepmc.org/articles/PMC1523400/
https://europepmc.org/articles/PMC1523400/