Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Daniel K. Fox"'
Autor:
Daniel Y. Johnson, R. J. Waken, Daniel K. Fox, Gmerice Hammond, Karen E. Joynt Maddox, Sharon Cresci
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 11 (2023)
Background Hypertrophic cardiomyopathy (HCM) is the most common heritable cardiac disease. In small studies, sociodemographic factors have been associated with disparities in septal reduction therapy, but little is known about the association of soci
Externí odkaz:
https://doaj.org/article/3eb300a8babd4901b49f0d24a0238fdf
Autor:
Daniel K. Fox, R. J. Waken, Daniel Y. Johnson, Gmerice Hammond, Jonathan Yu, Erika Fanous, Thomas M. Maddox, Karen E. Joynt Maddox
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 6 (2022)
Background Excess mortality from cardiovascular disease during the COVID‐19 pandemic has been reported. The mechanism is unclear but may include delay or deferral of care, or differential treatment during hospitalization because of strains on hospi
Externí odkaz:
https://doaj.org/article/8c45b864913646058faef04e49a50cb4
Publikováno v:
Journal of the American College of Cardiology. 77:864
Autor:
Steven A. Bullard, Daryl J. Murry, Daniel K. Fox, Jason M. Dierdorff, Christopher M. Adams, Kale S. Bongers, Michael C. Dyle, David K. Meyerholz, John J. Talley, Scott M. Ebert, Vitor A. Lira
Publikováno v:
The Journal of Biological Chemistry
Background: Aging reduces skeletal muscle strength and mass. Results: The transcription factor ATF4 is required for age-related muscle weakness and atrophy, and the small molecules ursolic acid and tomatidine reduce ATF4 activity, weakness, and atrop
Autor:
Scott M. Ebert, Daniel K. Fox, Steven D. Kunkel, Michael C. Dyle, Christopher M. Adams, Jason M. Dierdorff, Kale S. Bongers, Steven A. Bullard
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 307:E245-E261
Immobilization causes skeletal muscle atrophy via complex signaling pathways that are not well understood. To better understand these pathways, we investigated the roles of p53 and ATF4, two transcription factors that mediate adaptations to a variety
Autor:
Scott M. Ebert, Steven D. Kunkel, Christopher M. Adams, Steven A. Bullard, Michael C. Dyle, Daniel K. Fox, Jason M. Dierdorff, Daniel P. Cook, Kale S. Bongers
Publikováno v:
The Journal of Biological Chemistry
Background: Skeletal muscle atrophy is a common and serious condition that lacks a pharmacologic therapy. Results: We used a systems-based strategy to identify tomatidine, a natural compound from tomato plants, as a novel small molecule inhibitor of
Autor:
Jason M. Dierdorff, Kale S. Bongers, Christopher M. Adams, Steven A. Bullard, Steven D. Kunkel, Scott M. Ebert, Daniel K. Fox, Michael C. Dyle
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 305:E907-E915
Skeletal muscle denervation causes muscle atrophy via complex molecular mechanisms that are not well understood. To better understand these mechanisms, we investigated how muscle denervation increases growth arrest and DNA damage-inducible 45α ( Gad
Autor:
Scott M. Ebert, Eric D. Foster, Jason M. Dierdorff, Kale S. Bongers, Christopher M. Adams, Steven A. Bullard, Steven D. Kunkel, Michael C. Dyle, Daniel K. Fox
Publikováno v:
Journal of Biological Chemistry. 287:27290-27301
Diverse stresses including starvation and muscle disuse cause skeletal muscle atrophy. However, the molecular mechanisms of muscle atrophy are complex and not well understood. Here, we demonstrate that growth arrest and DNA damage-inducible 45a prote
Autor:
William I. Sivitz, Daniel K. Fox, Judy A. Herlein, Christopher M. Adams, Brian D. Fink, Manish Suneja
Hydroxymethylglutaryl coenzyme A reductase inhibitors (statins) prevent vascular events and are widely prescribed, particularly in persons with type 2 diabetes. However, intolerability because of myopathic symptoms often limits their use. We investig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a227614a3b0ab9ec3a91efb304e061d4
https://europepmc.org/articles/PMC4509977/
https://europepmc.org/articles/PMC4509977/
Autor:
Steven D. Kunkel, Scott M. Ebert, Christopher M. Adams, Christopher J. Elmore, Steven A. Bullard, Michael C. Dyle, Daniel K. Fox, Kale S. Bongers
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39332 (2012)
PLoS ONE
PLoS ONE
Skeletal muscle Akt activity stimulates muscle growth and imparts resistance to obesity, glucose intolerance and fatty liver disease. We recently found that ursolic acid increases skeletal muscle Akt activity and stimulates muscle growth in non-obese