Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Daniel K. Everton"'
Autor:
Jennifer I. Brown, Peng Wang, Alan Y. L. Wong, Boryana Petrova, Rosanne Persaud, Sepideh Soukhtehzari, Melanie Lopez McDonald, Danielle Hanke, Josephine Christensen, Petar Iliev, Weiyuan Wang, Daniel K. Everton, Karla C. Williams, David A. Frank, Naama Kanarek, Brent D. G. Page
Publikováno v:
Metabolites, Vol 13, Iss 2, p 151 (2023)
Dihydrofolate reductase (DHFR) is an established anti-cancer drug target whose inhibition disrupts folate metabolism and STAT3-dependent gene expression. Cycloguanil was proposed as a DHFR inhibitor in the 1950s and is the active metabolite of clinic
Externí odkaz:
https://doaj.org/article/dc113ce5c5ce4058bae4c79c8ea7ac25
