Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Daniel K Wilton"'
Autor:
Michael S. Placzek, Daniel K. Wilton, Michel Weïwer, Mariah A. Manter, Sarah E. Reid, Christopher J. Meyer, Arthur J. Campbell, Besnik Bajrami, Antoine Bigot, Sarah Bricault, Agathe Fayet, Arnaud Frouin, Frederick Gergits, Mehak Gupta, Wei Jiang, Michelle Melanson, Chiara D. Romano, Misha M. Riley, Jessica M. Wang, Hsiao-Ying Wey, Florence F. Wagner, Beth Stevens, Jacob M. Hooker
Publikováno v:
ACS Central Science, Vol 10, Iss 5, Pp 1105-1114 (2024)
Externí odkaz:
https://doaj.org/article/5385c7c9d35c443787ef32334e8917b9
Autor:
W Christopher Risher, Sagar Patel, Il Hwan Kim, Akiyoshi Uezu, Srishti Bhagat, Daniel K Wilton, Louis-Jan Pilaz, Jonnathan Singh Alvarado, Osman Y Calhan, Debra L Silver, Beth Stevens, Nicole Calakos, Scott H Soderling, Cagla Eroglu
Publikováno v:
eLife, Vol 3 (2014)
During cortical synaptic development, thalamic axons must establish synaptic connections despite the presence of the more abundant intracortical projections. How thalamocortical synapses are formed and maintained in this competitive environment is un
Externí odkaz:
https://doaj.org/article/b90e1976a60c4962957813477cb052d4
Autor:
Lasse Dissing-Olesen, Alec J. Walker, Qian Feng, Helena J. Barr, Alicia C. Walker, Lili Xie, Daniel K. Wilton, Indrani Das, Larry I. Benowitz, Beth Stevens
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Although engulfment is a hallmark of microglia function, fully validated platforms that facilitate high-throughput quantification of this process are lacking. Here, we present FEAST (Flow cytometric Engulfment Assay for Specific Target prote
Externí odkaz:
https://doaj.org/article/8e693c8aa0b84be6a2269dca6bec6129
Autor:
Daniel K. Wilton, Beth Stevens
Publikováno v:
Neurobiology of Disease, Vol 143, Iss , Pp 104963- (2020)
Glial cells play critical roles in the normal development and function of neural circuits, but in many neurodegenerative diseases, they become dysregulated and may contribute to the development of brain pathology. In Huntington's disease (HD), glial
Externí odkaz:
https://doaj.org/article/aeb6c89ca64e4a1f85d05b61d3e494fb
Publikováno v:
Annual Review of Neuroscience. 42:107-127
Maturation of neuronal circuits requires selective elimination of synaptic connections. Although neuron-intrinsic mechanisms are important in this process, it is increasingly recognized that glial cells also play a critical role. Without proper funct
Autor:
Nicole Scott-Hewitt, Allie K. Muthukumar, Steven A. McCarroll, Matthew L. Baum, William Crotty, Arnaud Frouin, Rachel Fox, Toby Lanser, Bjarte Håvik, Matthew B. Johnson, Eugene Nacu, Kevin Eggan, David A. Sabatini, Alanna Carey, Chrysostomi Gialeli, Anna M. Blom, Elizabeth Bien, Frederick Gergits, Beth Stevens, Daniel K. Wilton
Schizophrenia risk is associated with increased gene copy number and brain expression of complement component 4 (C4). Because the complement system facilitates synaptic pruning, the C4 association has renewed interest in a hypothesis that excessive p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3fa70aec9d20e08958c65942d050df2
https://doi.org/10.1101/2020.09.11.291427
https://doi.org/10.1101/2020.09.11.291427
Autor:
Robyn S. Klein, Bette K. DeMasters, Joel R. Garbow, Daniel K. Wilton, James R. Bowen, Charise Garber, Arnaud Frouin, Denise A. Dorsey, Jinsheng Yu, Kenneth L. Tyler, Douglas M. Durrant, Mehul S. Suthar, Kristen E. Funk, Beth Stevens, Carlos J. Perez-Torres, Robert E. Schmidt, Michael J. Vasek, John K. Robinson, Steven Mennerick, Bryan Bollman, Xiaoping Jiang, Allison Soung
Publikováno v:
Nature. 534:538-543
Over 50% of patients who survive neuroinvasive infection with West Nile virus (WNV) exhibit chronic cognitive sequelae1,2. Although thousands of cases of WNV-mediated memory dysfunction accrue annually3, the mechanisms responsible for these impairmen
Autor:
Beth Stevens, Daniel K. Wilton
Publikováno v:
Neurobiology of Disease, Vol 143, Iss, Pp 104963-(2020)
Neurobiol Dis
Neurobiol Dis
Glial cells play critical roles in the normal development and function of neural circuits, but in many neurodegenerative diseases, they become dysregulated and may contribute to the development of brain pathology. In Huntington's disease (HD), glial
Autor:
Christina A. Welsh, Alec J. Walker, Emily K. Lehrman, Hisashi Umemori, Beth Stevens, Arnaud Frouin, Daniel K. Wilton, Chinfei Chen, Stephen T. Chang, Elizabeth Y. Litvina, Molly Heller
Publikováno v:
Neuron. 100(1)
Microglia regulate synaptic circuit remodeling and phagocytose synaptic material in the healthy brain; however, the mechanisms directing microglia to engulf specific synapses and avoid others remain unknown. Here, we demonstrate that an innate immune
Autor:
Emily K. Lehrman, Philipp Stawski, Mark H. Ellisman, Beth Stevens, Austin S. Draycott, Thomas J. Deerinck, Daniel K. Wilton, Ken H. Loh, Tanya Svinkina, Alice Y. Ting, Steven A. Carr, Namrata D. Udeshi
Publikováno v:
Cell, vol 166, iss 5
Cellular compartments that cannot be biochemically isolated are challenging to characterize. Here we demonstrate the proteomic characterization of the synaptic clefts that exist at both excitatory and inhibitory synapses. Normal brain function relies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fa5f01c3f431b7f6f4d87f59e7ab01
https://escholarship.org/uc/item/8g06864g
https://escholarship.org/uc/item/8g06864g