Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Daniel K Putnam"'
Autor:
Axel W Fischer, Sten Heinze, Daniel K Putnam, Bian Li, James C Pino, Yan Xia, Carlos F Lopez, Jens Meiler
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152517 (2016)
In silico prediction of a protein's tertiary structure remains an unsolved problem. The community-wide Critical Assessment of Protein Structure Prediction (CASP) experiment provides a double-blind study to evaluate improvements in protein structure p
Externí odkaz:
https://doaj.org/article/c470afaec60c4d41b25c2b17bc06434d
Autor:
Jinghui Zhang, Michael A. Dyer, Benjamin J. Raphael, Alberto S. Pappo, James R. Downing, Richard K. Wilson, Elaine R. Mardis, Xiang Chen, Ludmil B. Alexandrov, John Easton, Michael N. Edmonson, Donald A. Yergeau, Heather L. Mulder, Daniel K. Putnam, Michael Rusch, Scott Newman, Gang Wu, Gryte Satas, Armita Bahrami, Xiaotu Ma, Samuel W. Brady
To investigate the genomic evolution of metastatic pediatric osteosarcoma, we performed whole-genome and targeted deep sequencing on 14 osteosarcoma metastases and two primary tumors from four patients (two to eight samples per patient). All four pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::291e7ed8712a1ece2b30312e662a669c
https://doi.org/10.1158/1541-7786.c.6541300
https://doi.org/10.1158/1541-7786.c.6541300
Autor:
Jinghui Zhang, Michael A. Dyer, Benjamin J. Raphael, Alberto S. Pappo, James R. Downing, Richard K. Wilson, Elaine R. Mardis, Xiang Chen, Ludmil B. Alexandrov, John Easton, Michael N. Edmonson, Donald A. Yergeau, Heather L. Mulder, Daniel K. Putnam, Michael Rusch, Scott Newman, Gang Wu, Gryte Satas, Armita Bahrami, Xiaotu Ma, Samuel W. Brady
Osteosarcoma clinical history and capture validation sequencing data. Supplementary Table S1. Sample and treatment information for relapsed osteosarcoma patients. Supplementary Table S2. SJOS0011101 SNVs detected by capture validation and tumor purit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76dbef3bc2181052065972df64c165b
https://doi.org/10.1158/1541-7786.22516159
https://doi.org/10.1158/1541-7786.22516159
Publikováno v:
Cancer Research. 82:1936-1936
Gene regulation is critical for cell identity, and its dysregulation is a defining characteristic of common diseases including cancers. Although promoter activity is a strong predictor of gene expression, activities at other regulatory elements, incl
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 8, Iss 11 (2013)
Small angle X-ray scattering (SAXS) is used for low resolution structural characterization of proteins often in combination with other experimental techniques. After briefly reviewing the theory of SAXS we discuss computational methods based on 1) th
Externí odkaz:
https://doaj.org/article/8348fb4c0d294042a3c69867f8738a42
Autor:
Paul Langan, Candace H. Haigler, Hugh O'Neill, Udaya C. Kalluri, Loukas Petridis, Jens Meiler, William T. Heller, B. Tracy Nixon, Qiu Zhang, Daniel K. Putnam, Jeremy C. Smith, Leighton Coates, Venu Gopal Vandavasi
Publikováno v:
Plant Physiology. 170:123-135
A cellulose synthesis complex with a "rosette" shape is responsible for synthesis of cellulose chains and their assembly into microfibrils within the cell walls of land plants and their charophyte algal progenitors. The number of cellulose synthase p
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 83:1500-1512
Small angle X-ray scattering (SAXS) is an experimental technique used for structural characterization of macromolecules in solution. Here, we introduce BCL::SAXS – an algorithm designed to replicate SAXS profiles from rigid protein models at differ
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 83:547-563
During CASP10 in summer 2012, we tested BCL::Fold for prediction of free modeling (FM) and template-based modeling (TBM) targets. BCL::Fold assembles the tertiary structure of a protein from predicted secondary structure elements (SSEs) omitting more
Autor:
Sten Heinze, Jens Meiler, James C. Pino, Carlos F. Lopez, Axel Fischer, Daniel K. Putnam, Yan Xia, Bian Li
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 4, p e0152517 (2016)
PLoS ONE, Vol 11, Iss 4, p e0152517 (2016)
In silico prediction of a protein’s tertiary structure remains an unsolved problem. The community-wide Critical Assessment of Protein Structure Prediction (CASP) experiment provides a double-blind study to evaluate improvements in protein structure
Publikováno v:
Proteins. 83(8)
Small angle X-ray scattering (SAXS) is an experimental technique used for structural characterization of macromolecules in solution. Here, we introduce BCL::SAXS--an algorithm designed to replicate SAXS profiles from rigid protein models at different