Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Daniel K Fox"'
Autor:
Steven D Kunkel, Christopher J Elmore, Kale S Bongers, Scott M Ebert, Daniel K Fox, Michael C Dyle, Steven A Bullard, Christopher M Adams
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39332 (2012)
Skeletal muscle Akt activity stimulates muscle growth and imparts resistance to obesity, glucose intolerance and fatty liver disease. We recently found that ursolic acid increases skeletal muscle Akt activity and stimulates muscle growth in non-obese
Externí odkaz:
https://doaj.org/article/03afc48475714e049b8048a5ea5d18c7
Autor:
Bruce S Hostager, Daniel K Fox, Douglas Whitten, Curtis G Wilkerson, Betty A Eipper, Victor P Francone, Paul B Rothman, John D Colgan
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e11380 (2010)
The tumor necrosis factor receptor (TNFR) superfamily mediates signals critical for regulation of the immune system. One family member, CD40, is important for the efficient activation of antibody-producing B cells and other antigen-presenting cells.
Externí odkaz:
https://doaj.org/article/86d4cc668d754adb959614d8440bd1e6
Autor:
Daniel Y. Johnson, R. J. Waken, Daniel K. Fox, Gmerice Hammond, Karen E. Joynt Maddox, Sharon Cresci
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 11 (2023)
Background Hypertrophic cardiomyopathy (HCM) is the most common heritable cardiac disease. In small studies, sociodemographic factors have been associated with disparities in septal reduction therapy, but little is known about the association of soci
Externí odkaz:
https://doaj.org/article/3eb300a8babd4901b49f0d24a0238fdf
Autor:
Daniel K. Fox, R. J. Waken, Daniel Y. Johnson, Gmerice Hammond, Jonathan Yu, Erika Fanous, Thomas M. Maddox, Karen E. Joynt Maddox
Publikováno v:
Journal of the American Heart Association. 11
Background Excess mortality from cardiovascular disease during the COVID‐19 pandemic has been reported. The mechanism is unclear but may include delay or deferral of care, or differential treatment during hospitalization because of strains on hospi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4351158dcc12e8033086422df1491c88
https://doi.org/10.1161/jaha.121.022625
https://doi.org/10.1161/jaha.121.022625
Publikováno v:
Journal of the American College of Cardiology. 77:864
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4006caa07488c2188a436b13cceea9b
https://doi.org/10.1016/s0735-1097(21)02223-3
https://doi.org/10.1016/s0735-1097(21)02223-3
Autor:
Steven A. Bullard, Daryl J. Murry, Daniel K. Fox, Jason M. Dierdorff, Christopher M. Adams, Kale S. Bongers, Michael C. Dyle, David K. Meyerholz, John J. Talley, Scott M. Ebert, Vitor A. Lira
Publikováno v:
The Journal of Biological Chemistry
Background: Aging reduces skeletal muscle strength and mass. Results: The transcription factor ATF4 is required for age-related muscle weakness and atrophy, and the small molecules ursolic acid and tomatidine reduce ATF4 activity, weakness, and atrop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fd5905feec44a2516502d0e1ea01096
https://doi.org/10.1074/jbc.m115.681445
https://doi.org/10.1074/jbc.m115.681445
Autor:
Scott M. Ebert, Daniel K. Fox, Steven D. Kunkel, Michael C. Dyle, Christopher M. Adams, Jason M. Dierdorff, Kale S. Bongers, Steven A. Bullard
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 307:E245-E261
Immobilization causes skeletal muscle atrophy via complex signaling pathways that are not well understood. To better understand these pathways, we investigated the roles of p53 and ATF4, two transcription factors that mediate adaptations to a variety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9460ffb6fce4c48e1e79790f752c1c
https://doi.org/10.1152/ajpendo.00010.2014
https://doi.org/10.1152/ajpendo.00010.2014
Autor:
Scott M. Ebert, Steven D. Kunkel, Christopher M. Adams, Steven A. Bullard, Michael C. Dyle, Daniel K. Fox, Jason M. Dierdorff, Daniel P. Cook, Kale S. Bongers
Publikováno v:
The Journal of Biological Chemistry
Background: Skeletal muscle atrophy is a common and serious condition that lacks a pharmacologic therapy. Results: We used a systems-based strategy to identify tomatidine, a natural compound from tomato plants, as a novel small molecule inhibitor of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e2152d9a96b390d6bc53bb05de121d
http://europepmc.org/articles/PMC4031541
http://europepmc.org/articles/PMC4031541
Autor:
Jason M. Dierdorff, Kale S. Bongers, Christopher M. Adams, Steven A. Bullard, Steven D. Kunkel, Scott M. Ebert, Daniel K. Fox, Michael C. Dyle
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 305:E907-E915
Skeletal muscle denervation causes muscle atrophy via complex molecular mechanisms that are not well understood. To better understand these mechanisms, we investigated how muscle denervation increases growth arrest and DNA damage-inducible 45α ( Gad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c3ba96cfb504a0f798834581c8c44d
https://doi.org/10.1152/ajpendo.00380.2013
https://doi.org/10.1152/ajpendo.00380.2013
Autor:
Scott M. Ebert, Eric D. Foster, Jason M. Dierdorff, Kale S. Bongers, Christopher M. Adams, Steven A. Bullard, Steven D. Kunkel, Michael C. Dyle, Daniel K. Fox
Publikováno v:
Journal of Biological Chemistry. 287:27290-27301
Diverse stresses including starvation and muscle disuse cause skeletal muscle atrophy. However, the molecular mechanisms of muscle atrophy are complex and not well understood. Here, we demonstrate that growth arrest and DNA damage-inducible 45a prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac572a7b77827379d55a11d7d982cef6
https://doi.org/10.1074/jbc.m112.374777
https://doi.org/10.1074/jbc.m112.374777