Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Daniel Johnstone"'
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45535 (2012)
BackgroundOne primary goal of transcriptomic studies is identifying gene expression patterns correlating with disease progression. This is usually achieved by considering transcripts that independently pass an arbitrary threshold (e.g. pMethodology/p
Externí odkaz:
https://doaj.org/article/29a128d48b8b406a80eed3bbf289bd15
Autor:
Daniel Johnstone, Elizabeth A Milward, Regina Berretta, Pablo Moscato, Alzheimer's Disease Neuroimaging Initiative
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34341 (2012)
BACKGROUND:Recent Alzheimer's disease (AD) research has focused on finding biomarkers to identify disease at the pre-clinical stage of mild cognitive impairment (MCI), allowing treatment to be initiated before irreversible damage occurs. Many studies
Externí odkaz:
https://doaj.org/article/db644552a6f040299eb34ee37b8a703e
Autor:
Andrew Zodda, Sheri Li, Christopher Daniel Johnstone, Mariana B Martins, Xinrong Ma, Kayla M. Tighe, Kavita Bhalla, Eduardo Solano-Gonzalez, Andrea Casildo, Palak R Parekh, Javed Mahmood, Yannick Poirier, Rena G. Lapidus
Publikováno v:
Cancers
Volume 13
Issue 16
Cancers, Vol 13, Iss 4186, p 4186 (2021)
Volume 13
Issue 16
Cancers, Vol 13, Iss 4186, p 4186 (2021)
Treatment options are rather limited for gastrointestinal cancer patients whose disease has disseminated into the intra-abdominal cavity. Here, we designed pre-clinical studies to evaluate the potential application of chemopotentiation by Low Dose Fr
Publikováno v:
Bioresource Technology Reports. 19:101169
Autor:
Spencer Bialek, Boris Vojnovic, Dylan Y. Breitkreutz, Christopher Daniel Johnstone, Paul Tsouchlos, Anthony Kavanagh, Zach Rovner, Thilakshan Kanesalingam, Magdalena Bazalova-Carter
Publikováno v:
Medical Physics. 46:2015-2024
The goal of this work was to develop and test a cylindrical tissue-equivalent quality assurance (QA) phantom for micro computed tomography (microCT) image-guided small animal irradiators that overcomes deficiencies of existing phantoms due to its mou
Autor:
S.J. Becker, Zeljko Vujaskovic, Andrew J. Gerry, Christopher Daniel Johnstone, E. Draeger, Wesley S. Culberson, C. DeCesaris, Isabel L Jackson, Yannick Poirier, Allison Gibbs
Publikováno v:
Radiation Research. 194
Animal models of total-body irradiation (TBI) are used to elucidate normal tissue damage and evaluate the efficacy of medical countermeasures (MCM). The accuracy of these TBI models depends on the reproducibility of the radiation dose-response relati
Autor:
A Rubinstein, Youssef Ben-Bouchta, Jessica R. Perez, Magdalena Bazalova-Carter, Patricia Lindsay, Edward E. Graves, Haijian Chen, Christopher Daniel Johnstone, Eugene Wong, Yannick Poirier, Ke Sheng, Thilakshan Kanesalingam
Publikováno v:
Physics in medicine and biology, vol 62, iss 14
To recommend imaging protocols and establish tolerance levels for microCT image quality assurance (QA) performed on conformal image-guided small animal irradiators. A fully automated QA software SAPA (small animal phantom analyzer) for image analysis
Autor:
Yannick Poirier, Akbar Anvari, N. Patrik Brodin, Magdalena Bazalova-Carter, Christopher Daniel Johnstone, Morgane Dos Santos, Amit Sawant
Publikováno v:
Medical physicsReferences. 47(4)
Purpose Image-guided small animal irradiators (IGSAI) are increasingly being adopted in radiation biology research. These animal irradiators, designed to deliver radiation with submillimeter accuracy, exhibit complexity similar to that of clinical ra
Autor:
Daniel Johnstone, Hayden Marcollo, Tricia Hill, Andrew E. Potts, Andrew Kilner, Peter Pezet, Phillip P. Kurts
Publikováno v:
Volume 5B: Pipelines, Risers, and Subsea Systems.
Instrumented field trials of Longitudinally Grooved Suppression (LGS) VIV suppression buoyancy modules have been completed on deep water drilling risers in the Gulf of Mexico. The field trials were used to validate the performance of the technology,
Publikováno v:
Physics in medicine and biology. 63(17)
Microbeam radiation therapy (MRT) is a pre-clinical, spatially-fractionated treatment modality noted for its ability to achieve a large differential response between normal and tumoral tissues. In the present study, TOPAS Monte Carlo (MC) simulations