Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Daniel J. Tozer"'
Autor:
Christopher N. Osuafor, Catarina Rua, Andrew D. Mackinnon, Marco Egle, Philip Benjamin, Daniel J. Tozer, Christopher T. Rodgers, Hugh S. Markus
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract 7 Tesla-field-strength (7 T) Magnetic Resonance Imaging allows the small perforating arteries in the brain to be visualised, and this modality may allow visualisation of the arterial pathology in cerebral small vessel disease. Most studies h
Externí odkaz:
https://doaj.org/article/edec8c3a7f954c6e8ed75f0e4f82e61a
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Complex brain networks play a central role in integrating activity across the human brain, and such networks can be identified in the absence of any external stimulus. We performed 10 genome-wide association studies of resting state network
Externí odkaz:
https://doaj.org/article/4b123fa74a6c4ad49e4282c62749fa1d
Autor:
Rui Li, Eric L. Harshfield, Steven Bell, Michael Burkhart, Anil M. Tuladhar, Saima Hilal, Daniel J. Tozer, Francesca M. Chappell, Stephen D.J. Makin, Jessica W. Lo, Joanna M. Wardlaw, Frank-Erik de Leeuw, Christopher Chen, Zoe Kourtzi, Hugh S. Markus
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 5, Iss , Pp 100179- (2023)
Background: Cerebral small vessel disease (SVD) contributes to 45% of dementia cases worldwide, yet we lack a reliable model for predicting dementia in SVD. Past attempts largely relied on traditional statistical approaches. Here, we investigated whe
Externí odkaz:
https://doaj.org/article/f6fd45ab5ab94d0f8ed7bd9079eaaa94
Autor:
Yi Lin Ng, Chuen Seng Tan, Marco Egle, Bibek Gyanwali, Daniel J. Tozer, Hugh S. Markus, Christopher Chen, Saima Hilal
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 5, Iss , Pp 100174- (2023)
Objective: Median and peak height of fractional anisotropy (FA) and mean diffusivity (MD) are diffusion tensor imaging (DTI) markers used to quantify white matter microstructure changes. We examine the association of DTI histogram-derived measures in
Externí odkaz:
https://doaj.org/article/af89a68d17194026892a7600caec7122
Publikováno v:
Cerebral Circulation - Cognition and Behavior, Vol 4, Iss , Pp 100167- (2023)
Abnormalities in structural and functional MRI connectivity measures have been reported in cerebral small vessel disease (SVD). Previous research has shown that whole-brain structural connectivity was highly reproducible in SVD patients, while whole-
Externí odkaz:
https://doaj.org/article/545ada89c9364675b220e2e53821f244
Autor:
Vaanathi Sundaresan, Christoph Arthofer, Giovanna Zamboni, Robert A. Dineen, Peter M. Rothwell, Stamatios N. Sotiropoulos, Dorothee P. Auer, Daniel J. Tozer, Hugh S. Markus, Karla L. Miller, Iulius Dragonu, Nikola Sprigg, Fidel Alfaro-Almagro, Mark Jenkinson, Ludovica Griffanti
Publikováno v:
Frontiers in Neuroinformatics, Vol 15 (2022)
Cerebral microbleeds (CMBs) appear as small, circular, well defined hypointense lesions of a few mm in size on T2*-weighted gradient recalled echo (T2*-GRE) images and appear enhanced on susceptibility weighted images (SWI). Due to their small size,
Externí odkaz:
https://doaj.org/article/e99c1c9646054444a8d754f0b750e112
Publikováno v:
NeuroImage: Clinical, Vol 18, Iss , Pp 425-432 (2018)
Objective: MRI measures of network integrity may be useful disease markers in cerebral small vessel disease (SVD). We compared the sensitivity and reproducibility of MRI derived structural and functional network measures in healthy controls and SVD s
Externí odkaz:
https://doaj.org/article/f00f86490781485083f4930b704812cf
Abnormalities in structural and functional MRI connectivity measures have been reported in cerebral small vessel disease (SVD). Previous research has shown that whole-brain structural connectivity was highly reproducible in SVD patients, while whole-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e130a54f836c9e253311941e9d2711af
https://www.repository.cam.ac.uk/handle/1810/350894
https://www.repository.cam.ac.uk/handle/1810/350894
Autor:
Robin B Brown, Daniel J Tozer, Laurence Loubière, Young T Hong, Tim D Fryer, Guy B Williams, Martin J Graves, Franklin I Aigbirhio, John T O’Brien, Hugh S Markus
Background: Cerebral small vessel disease (SVD) is a common cause of stroke and cognitive impairment. Recent data has implicated neuroinflammation and increased blood-brain barrier (BBB) permeability in its pathogenesis, but whether such processes ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1db684e62df570286c9af69f1b908f6
Autor:
Robin B Brown, Daniel J Tozer, Marco Egle, Anil M Tuladhar, Frank-Erik de Leeuw, Hugh S Markus
Publikováno v:
International Journal of Stroke. :174749302311691
Background and objectives: It has been suggested that white matter hyperintensity lesions (WMHs), which typically progress over time, can also regress, and that this might be associated with favorable cognitive performance. We determined the prevalen