Zobrazeno 1 - 10 of 33 pro vyhledávání: '"Daniel J. Tetlow"'
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Sequence-Selective Decapeptide Synthesis by the Parallel Operation of Two Artificial Molecular Machines
Autor: Chong Tian, Daniel J. Tetlow, Malcolm A. Y. Gall, Javier Echavarren, Justin T J Spence, David A. Leigh, Adrian Haertsch
Publikováno v: Journal of the American Chemical Society
We report on the preparation of a decapeptide through the parallel operation of two rotaxane-based molecular machines. The synthesis proceeds in four stages: (1) simultaneous operation of two molecular peptide synthesizers in the same reaction vessel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04960f64593b6301e7fbaa4e0b3bf47
https://doi.org/10.1021/jacs.1c01234
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4
Site-to-site peptide transport on a molecular platform using a small-molecule robotic arm†
Autor: Naoyuki Toriumi, Daniel J. Tetlow, Augustinas Markevicius, David A. Leigh, Alan T. L. Lee, Salma Kassem
Publikováno v: Chemical Science
Kassem, S, Lee, A T L, Leigh, D A, Markevicius, A, Tetlow, D J & Toriumi, N 2020, ' Site-to-site peptide transport on a molecular platform using a small-molecule robotic arm ', Chemical Science, vol. 12, no. 6, pp. 2065-2070 . https://doi.org/10.1039/D0SC05906D
Peptides attached to a cysteine hydrazide ‘transporter module’ are transported selectively in either direction between two chemically similar sites on a molecular platform, enabled by the discovery of new operating methods for a molecular transpo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb348c50f2c5e70f1aafbc85251863e6
http://europepmc.org/articles/PMC8179245
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5
Active template rotaxane synthesis through the Ni-catalyzed cross-coupling of alkylzinc reagents with redox-active esters
Autor: Javier Echavarren, Adrian Haertsch, Malcolm A. Y. Gall, Vanesa Marcos, Daniel J. Tetlow, David A. Leigh
Publikováno v: Chemical Science
Echavarren, J, Gall, M A Y, Haertsch, A, Leigh, D A, Marcos, V & Tetlow, D J 2019, ' Active template rotaxane synthesis through the Ni-catalyzed cross-coupling of alkylzinc reagents with redox-active esters ', Chemical Science, vol. 10, no. 30, pp. 7269-7273 . https://doi.org/10.1039/c9sc02457c
The Ni-catalyzed C(sp3)–C(sp3) cross-coupling of redox-active esters and organozinc reagents is used for the active template synthesis of ‘impossible’ rotaxanes.
The synthesis of unsymmetrical axle [2]rotaxanes through a recently developed
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4b1d856385a5500c62d97213553b3f
https://doi.org/10.1039/c9sc02457c
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6
Rotary and linear molecular motors driven by pulses of a chemical fuel
Autor: Ulvi Karaca, Charlie T. McTernan, Miriam R. Wilson, Sundus Erbas-Cakmak, Daniel J. Tetlow, David A. Leigh, Stephen D. P. Fielden
Publikováno v: Erbas-Cakmak, S, Fielden, S D P, Karaca, U, Leigh, D A, McTernan, C T, Tetlow, D J & Wilson, M R 2017, ' Rotary and linear molecular motors driven by pulses of a chemical fuel ', Science, vol. 358, no. 6361, pp. 340-343 . https://doi.org/10.1126/science.aao1377
Acid fuels the motion of a threaded ring A central goal in the construction of molecular-scale machines is the efficient achievement of one-way motion. Erbas-Cakmak et al. developed a class of machines that transmit pH changes into the two-stage guid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c74dfb307e3e6a9dd8b9f1de5f62f780
https://doi.org/10.1126/science.aao1377
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7
Sequence-Specific β-Peptide Synthesis by a Rotaxane-Based Molecular Machine
Autor: John W. Ward, Malcolm A. Y. Gall, Sonja Kuschel, Daniel J. Tetlow, Matthew O. Kitching, Guillaume De Bo, David A. Leigh
Publikováno v: Journal of the American Chemical Society, 2017, Vol.139(31), pp.10875-10879 [Peer Reviewed Journal]
De Bo, G, Gall, M, Kitching, M, Kuschel, S, Leigh, D, Tetlow, D & Ward, J 2017, ' Sequence-Specific Beta-Peptide Synthesis by a Rotaxane-Based Molecular Machine ', American Chemical Society. Journal . https://doi.org/10.1021/jacs.7b05850
We report on the synthesis and operation of a three-barrier, rotaxane-based, artificial molecular machine capable of sequence-specific beta-homo (β3) peptide synthesis. The machine utilizes non-proteinogenic β3-amino acids, a class of amino acids n
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5f0161018af06c4f0ac51afe3710a6
https://doi.org/10.1021/jacs.7b05850
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10
Securing a Supramolecular Architecture by Tying a Stopper Knot
Autor: David A. Leigh, Lucian Pirvu, Fredrik Schaufelberger, Daniel J. Tetlow, Liang Zhang
Publikováno v: Angewandte Chemie (International Ed. in English)
Leigh, D, Pirvu, L, Schaufelberger, F, Tetlow, D & Zhang, L 2018, ' Securing a Supramolecular Architecture By Tying a Stopper Knot ', Angewandte Chemie . https://doi.org/10.1002/ange.201803871
We report on a rotaxane‐like architecture secured by the in situ tying of an overhand knot in the tris(2,6‐pyridyldicarboxamide) region of the axle through complexation with a lanthanide ion (Lu3+). The increase in steric bulk caused by the knott
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e25e6048b8ae2da88de62b734a42080
https://pubmed.ncbi.nlm.nih.gov/29708636
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