Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Daniel J. Saltzberg"'
Autor:
Atefeh Rafiei, Sofía Cruz Tetlalmatzi, Claire H Edrington, Linda Lee, D Alex Crowder, Daniel J Saltzberg, Andrej Sali, Gary Brouhard, David C Schriemer
Publikováno v:
eLife, Vol 11 (2022)
Doublecortin (DCX) is a microtubule (MT)-associated protein that regulates MT structure and function during neuronal development and mutations in DCX lead to a spectrum of neurological disorders. The structural properties of MT-bound DCX that explain
Externí odkaz:
https://doaj.org/article/c0c1f63c70ab443d8a4198aa65ca6e7b
Autor:
Andrej Sali, Ignacia Echeverria, Shruthi Viswanath, Ilan E. Chemmama, Daniel J. Saltzberg, Ben Webb
Publikováno v:
Protein Sci
Biology is advanced by producing structural models of biological systems, such as protein complexes. Some systems are recalcitrant to traditional structure determination methods. In such cases, it may still be possible to produce useful models by int
Autor:
Atefeh Rafiei, Sofía Cruz Tetlalmatzi, Claire H Edrington, Linda Lee, D Alex Crowder, Daniel J Saltzberg, Andrej Sali, Gary Brouhard, David C Schriemer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cce8fffffa962b2181db1c13c8685f1
https://doi.org/10.7554/elife.66975.sa2
https://doi.org/10.7554/elife.66975.sa2
Autor:
Sue L. Jaspersen, Fei Fang, Christina Ouch, Ilona Nudelman, Kankang Song, Sergey Suslov, Yi Shi, Javier Menendez-Martinez, Brian T. Chait, Andrej Sali, Ignacia Echeverria, Daniel J. Saltzberg, Digvijay Singh, Joseph M. Varberg, Steven J Ludke, Chen Xu, Elizabeth Villa, Zuliin Yu, Christopher W. Akey, James C. Gumbart, Jay R. Unruh, Michael P. Rout, Junjie Wang
Publikováno v:
Cell, vol 185, iss 2
Nuclear pore complexes (NPCs) mediate the nucleocytoplasmic transport of macromolecules. Here we provide a structure of the isolated yeast NPC in which the inner ring is resolved by cryo-EM at sub-nanometer resolution to show how flexible connectors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd173aeefd16aec055b90bd1b49d79e4
https://doi.org/10.1101/2021.10.29.466335
https://doi.org/10.1101/2021.10.29.466335
Autor:
Daniel S. Ziemianowicz, Daniel J. Saltzberg, D. Alex Crowder, Christoph U. Schräder, Andrej Sali, Troy J. Pells, Morgan Hepburn, David C. Schriemer
Publikováno v:
Molecular & Cellular Proteomics : MCP
Proteomics methodology has expanded to include protein structural analysis, primarily through cross-linking mass spectrometry (XL-MS) and hydrogen–deuterium exchange mass spectrometry (HX-MS). However, while the structural proteomics community has
Autor:
Hyunil Jo, William F. DeGrado, Daniel J. Saltzberg, Haifan Wu, Huong T. Kratochvil, Andrej Sali
Publikováno v:
Journal of the American Chemical Society, vol 141, iss 18
Infrared (IR) spectroscopy has provided considerable insight into the structures, dynamics, and formation mechanisms of amyloid fibrils. IR probes, such as main chain (13)C=(18)O, have been widely employed to obtain site-specific structural informati
Autor:
Jeremiah D Farelli, Brendan D Galvin, Zhiru Li, Chunliang Liu, Miyuki Aono, Megan Garland, Olivia E Hallett, Thomas B Causey, Alana Ali-Reynolds, Daniel J Saltzberg, Clotilde K S Carlow, Debra Dunaway-Mariano, Karen N Allen
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004245 (2014)
Parasitic nematodes are responsible for devastating illnesses that plague many of the world's poorest populations indigenous to the tropical areas of developing nations. Among these diseases is lymphatic filariasis, a major cause of permanent and lon
Externí odkaz:
https://doaj.org/article/56597a01f85b41e98e0b6236a99ece68
Autor:
Linda Lee, D. Alex Crowder, Andrej Sali, Daniel J. Saltzberg, Atefeh Rafiei, Gary J. Brouhard, David C. Schriemer
Doublecortin (DCX) is a microtubule (MT) associated protein that regulates MT structure and function during neuronal development and mutations in DCX lead to a spectrum of neurological disorders. The structural properties of MT-bound DCX remain poorl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d933529675ddf82c93d28bb21a6cc664
https://doi.org/10.1101/2021.02.17.431714
https://doi.org/10.1101/2021.02.17.431714
Autor:
Linda Lee, David C. Schriemer, Susan P. Lees-Miller, Natalie C. J. Strynadka, Morgan Hepburn, Shujuan Fang, Claire E. Atkinson, Andrej Sali, Daniel J. Saltzberg
Publikováno v:
Structure
Structure (London, England : 1993), vol 29, iss 5
Structure (London, England : 1993), vol 29, iss 5
In the non-homologous end joining (NHEJ) of a DNA double strand break, DNA ends are bound and protected by a large heterotrimeric DNA-PK complex, which synapses across the break to tether the broken ends and initiate the repair program. There is a la
Autor:
Pedro Beltrao, Phillip P. Sharp, Nevan J. Krogan, Sabrina J. Fletcher, Saker Klippsten, Trey Ideker, Melanie Ott, Bryan L. Roth, Xi Liu, Devin A. Cavero, Djoshkun Shengjuler, Christopher J.P. Mathy, Jason C.J. Chang, Theodore L. Roth, Hannes Braberg, Claudia Hernandez-Armenta, Lisa Miorin, Jyoti Batra, Shizhong Dai, Maliheh Safari, Brian K. Shoichet, Danish Memon, Tia A. Tummino, Marco Vignuzzi, Mark von Zastrow, Manon Eckhardt, Alan D. Frankel, Qiongyu Li, Tanja Kortemme, Nicole A. Wenzell, Zun Zar Chi Naing, Ferdinand Roesch, Nastaran Sadat Savar, Mathieu Hubert, Xi Ping Huang, Elena Moreno, Danica Galonić Fujimori, Jeffrey Z. Guo, Natalia Jura, Kirsten Obernier, Kliment A. Verba, Harmit S. Malik, Hao-Yuan Wang, Michael McGregor, Melanie J. Bennett, Julia Noack, Gwendolyn M. Jang, Paige Haas, Alice Mac Kain, Daniel J. Saltzberg, Mehdi Bouhaddou, Ziyang Zhang, Yongfeng Liu, Inigo Barrio-Hernandez, Yiming Cai, Kris M. White, Kelsey M. Haas, Maya Modak, Stephanie A. Wankowicz, Raphael Trenker, Kevan M. Shokat, Fatima S. Ugur, Shiming Peng, Sai J. Ganesan, Shaeri Mukherjee, Yuan Zhou, Minkyu Kim, John D. Gross, Jack Taunton, Alicia L. Richards, John S. Chorba, Margaret Soucheray, Danielle L. Swaney, Benjamin J. Polacco, Alan Ashworth, Wenqi Shen, Adolfo García-Sastre, Merve Cakir, Ujjwal Rathore, Kala Bharath Pilla, Michael C. O’Neal, Ying Shi, Kevin Lou, Cassandra Koh, Stephen N. Floor, Davide Ruggero, Ilsa T Kirby, Srivats Venkataramanan, Ruth Hüttenhain, Olivier Schwartz, Beril Tutuncuoglu, Christophe d'Enfert, Jose Liboy-Lugo, David A. Agard, Charles S. Craik, Veronica V. Rezelj, Tina Perica, Matthew P. Jacobson, Lorenzo Calviello, Eric Verdin, Yizhu Lin, Jiankun Lyu, Jiewei Xu, Joseph Hiatt, Andrej Sali, Oren S. Rosenberg, Markus Bohn, David E. Gordon, James S. Fraser, Sara Brin Rosenthal, Duygu Kuzuoğlu-Öztürk, Robyn M. Kaake, Jacqueline M. Fabius, Matthew J. O’Meara, Quang Dinh Tran, Advait Subramanian, Thomas Vallet, Bjoern Meyer, James E. Melnyk, Robert M. Stroud, Helene Foussard, Rakesh Ramachandran, David J. Broadhurst, Janet M. Young, Michael Emerman
Publikováno v:
Nature
Schizophrenia Research
Schizophrenia Research
A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019 (COVID-19), has infected over 2.3 million people, led to the death of more than 160,000 individ