Zobrazeno 1 - 10 of 40 pro vyhledávání: '"Daniel J. Riley"'
1
Aberrant DNA damage response and DNA repair pathway in high glucose conditions
Autor: Raymond Gau, Melissa Chang, Daniel J. Riley, Phang Lang Chen, Yumay Chen, Theresa Yu, Amy Zhong
Publikováno v: Zhong, Amy; Chang, Melissa; Yu, Theresa; Gau, Raymond; Riley, Daniel J; Chen, Yumay; et al.(2018). Aberrant DNA damage response and DNA repair pathway in high glucose conditions.. Journal of cancer research updates, 7(3), 64-74. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/5jf8k1rw
Journal of cancer research updates, vol 7, iss 3
Author(s): Zhong, Amy; Chang, Melissa; Yu, Theresa; Gau, Raymond; Riley, Daniel J; Chen, Yumay; Chen, Phang-Lang | Abstract: BackgroundHigher cancer rates and more aggressive behavior of certain cancers have been reported in populations with diabetes
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee89901e7e29613d5aea4b139c68d360
https://pubmed.ncbi.nlm.nih.gov/30498558
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2
Renal adaptation to the failing heart
Autor: Daniel J, Riley, Matthew, Weir, George L, Bakris
Publikováno v: Postgraduate medicine. 95(8)
Preview Selection of therapy for patients with systolic cardiac dysfunction must be predicated on careful assessment of the delicate interplay between the failing heart and the state of effective circulating blood volume. In this article, the authors
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0dbc0986f69ea29275e869e654c70ffc
https://pubmed.ncbi.nlm.nih.gov/29211605
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3
Nek1 regulates cell death and mitochondrial membrane permeability through phosphorylation of VDAC1
Autor: William J. Craigen, Yumay Chen, Daniel J. Riley
Publikováno v: Cell Cycle. 8:257-267
The mammalian NIMA-related protein kinase 1 (Nek1) is important for keeping cells alive after DNA damage, but the mechanism by which injured cells die without functional Nek1 has not yet been demonstrated. Here we show that Nek1 regulates the pathway
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4220266fc8e450ca1a9b9c0d68334a
https://doi.org/10.4161/cc.8.2.7551
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4
Never-in-mitosis related Kinase 1 functions in DNA damage response and checkpoint control
Autor: Chi Fen Chen, Phang Lang Chen, Yumay Chen, Xianzhi Jiang, Daniel J. Riley
Publikováno v: Cell Cycle. 7:3194-3201
Nek1, the first mammalian ortholog of the fungal protein kinase never in mitosis A, is involved early in the DNA damage sensing/repair pathway after ionizing radiation. Here we extend this finding by showing that Nek1 localizes to nuclear foci of DNA
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1c56f5704c3f63b74c68afbf1040cc
https://doi.org/10.4161/cc.7.20.6815
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5
Raptor-rictor axis in TGFβ-induced protein synthesis
Autor: Balachandar Venkatesan, Daniel J. Riley, Denis Feliers, Falguni Das, Goutam Ghosh Choudhury, Balakuntalam S. Kasinath, Nandini Ghosh-Choudhury, Lenin Mahimainathan
Publikováno v: Cellular Signalling. 20:409-423
Transforming growth factor-beta (TGFbeta) stimulates pathological renal cell hypertrophy for which increased protein synthesis is critical. The mechanism of TGFbeta-induced protein synthesis is not known, but PI 3 kinase-dependent Akt kinase activity
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df3c5a76b6298faf7c396a0b5ef0310
https://doi.org/10.1016/j.cellsig.2007.10.027
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6
Mitogenic Signaling via Platelet-Derived Growth Factor β in Metanephric Mesenchymal Cells
Autor: Karen Block, Yves Gorin, Goutam Ghosh Choudhury, Daniel J. Riley, Brent Wagner, Jill M. Ricono, Mazen Y Arar, Hanna E. Abboud
Publikováno v: Journal of the American Society of Nephrology. 18:2903-2911
Mice deficient in either platelet-derived growth factor (PDGF) B chain or PDGF receptor (PDGFR) beta lack mesangial cells. PDGF stimulates proliferation and migration of metanephric mesenchymal cells, from which mesangial cells are derived. Binding o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ebc7ac9333bee26ceb3b70690d819c0
https://doi.org/10.1681/asn.2006111229
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7
Human monocytic ehrlichiosis in a renal transplant patient
Autor: Barton Brezina, Nicholas G. Conger, Daniel J. Riley, Jason F. Okulicz, Casey L. Cotant
Publikováno v: Scandinavian Journal of Infectious Diseases. 38:699-702
Human ehrlichiosis is an emerging pathogen in immunocompromised patients, potentially leading to increased morbidity compared to immunocompetent patients. A high index of suspicion is imperative and early treatment with doxycycline can be life-saving
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db6130adc391cffc69fb69eca6055533
https://doi.org/10.1080/00365540500444694
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8
Prediction of GFR in liver transplant candidates
Autor: Pablo E. Pergola, Daniel J. Riley, Shuko Lee, Paul A. Skluzacek, Charles R. Nolan, Robert G. Szewc
Publikováno v: American Journal of Kidney Diseases. 42:1169-1176
Background: Kidney function frequently is impaired in patients with cirrhosis; however, glomerular filtration rate (GFR) is difficult to estimate in these patients by using standard clinical markers. The aim of our study is to compare GFR calculated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a5ab503682d56adca2d4a6f3d7873c
https://doi.org/10.1053/j.ajkd.2003.08.017
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9
Phosphorylation of the Mitotic Regulator Protein Hec1 by Nek2 Kinase Is Essential for Faithful Chromosome Segregation
Autor: Wen-Hwa Lee, Phang Lang Chen, Daniel J. Riley, Yumay Chen, Lei Zheng
Publikováno v: Journal of Biological Chemistry. 277:49408-49416
Hec1 (highly expressed in cancer) plays essential roles in chromosome segregation by interacting through its coiled-coil domains with several proteins that modulate the G(2)/M phase. Hec1 localizes to kinetochores, and its inactivation either by gene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2899cfdb32639534c4ba50b7150394
https://doi.org/10.1074/jbc.m207069200
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10
Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney disease
Autor: Charity Juang, Huai Chin Chiang, Patricia Litchfield, Yumay Chen, Michelle Pena, Daniel J. Riley
Publikováno v: Journal of biomedical science, vol 21, iss 1
Journal of Biomedical Science
Background Neks, mammalian orthologs of the fungal protein kinase never-in-mitosis A, have been implicated in the pathogenesis of polycystic kidney disease. Among them, Nek1 is the primary protein inactivated in kat2J mouse models of PKD. Result We r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007aa8214903098ce0869910702d9ec3
https://doi.org/10.1186/s12929-014-0063-5
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