Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Daniel J. M. Fernández-Ayala"'
Autor:
Juan Diego Hernández-Camacho, Daniel J. M. Fernández-Ayala, Cristina Vicente-García, Ignacio Navas-Enamorado, Guillermo López-Lluch, Clara Oliva, Rafael Artuch, Judith Garcia-Villoria, Antonia Ribes, Rafael de Cabo, Jaime J. Carvajal, Plácido Navas
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
ADCK2 haploinsufficiency-mediated mitochondrial coenzyme Q deficiency in skeletal muscle causes mitochondrial myopathy associated with defects in beta-oxidation of fatty acids, aged-matched metabolic reprogramming, and defective physical performance.
Externí odkaz:
https://doaj.org/article/315bb306e29740b48272f03feaab2a02
Autor:
Guillermo López-Lluch, Daniel J. M. Fernández-Ayala, Juan Diego Hernández-Camacho, Laura García-Corzo, Plácido Navas
Publikováno v:
Antioxidants, Vol 10, Iss 1785, p 1785 (2021)
Antioxidants
Antioxidants
© 2021 by the authors.
Coenzyme Q is a unique lipidic molecule highly conserved in evolution and essential to maintaining aerobic metabolism. It is endogenously synthesized in all cells by a very complex pathway involving a group of nuclear gen
Coenzyme Q is a unique lipidic molecule highly conserved in evolution and essential to maintaining aerobic metabolism. It is endogenously synthesized in all cells by a very complex pathway involving a group of nuclear gen
Autor:
Plácido, Navas, María V, Cascajo, María, Alcázar-Fabra, Juan D, Hernández-Camacho, Ana, Sánchez-Cuesta, Ana Belén Cortés, Rodríguez, Manuel, Ballesteros-Simarro, Antonio, Arroyo-Luque, Juan Carlos, Rodríguez-Aguilera, Daniel J M, Fernández-Ayala, Gloria, Brea-Calvo, Guillermo, López-Lluch, Carlos, Santos-Ocaña
Publikováno v:
BioFactors (Oxford, England)REFERENCES. 47(4)
Coenzyme Q
Publikováno v:
Mitochondrial Diseases ISBN: 9783030701468
The central role of mitochondria in cell metabolism and physiology is reflected in the diversity of functions that they perform within the cell. Alterations or imbalances in any of these cellular processes can cause mitochondrial dysfunction and dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f321e7ab2b9247531f2584660209ba7c
https://doi.org/10.1007/978-3-030-70147-5_10
https://doi.org/10.1007/978-3-030-70147-5_10
Publikováno v:
Experimental Gerontology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
SARS-CoV-2 causes a severe pneumonia (COVID-19) that affects essentially elderly people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense cytokine storm leading finally to a multi-organ failure and death. Comorbidities su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7078dc48f8fef463a574864856e9bc95
http://hdl.handle.net/10261/224591
http://hdl.handle.net/10261/224591
Publikováno v:
Coenzyme Q in Aging ISBN: 9783030456412
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Aging is the consequence of the gradual accumulation of molecular and cellular damage during life. Oxidative damage due to mitochondrial malfunction seems to be the main contributor to aging. Although, recently it has been propose that reverse electr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc9b8425c4d21dda5fb9bd704f19a590
http://hdl.handle.net/10261/230561
http://hdl.handle.net/10261/230561
Autor:
Plácido Navas, Guillermo López-Lluch, Juan Diego Hernández-Camacho, Daniel J. M. Fernández-Ayala
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
instname
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Mitochondria are key in the metabolism of aerobic organisms and in ageing progression and age-related diseases. Mitochondria are essential for obtaining ATP from glucose and fatty acids but also in many other essential functions in cells including am
Autor:
Manuel Portero-Otín, Oleh V. Lushchak, Plácido Navas, Daniel J. M. Fernández-Ayala, Alberto Sanz, Rhoda Stefanatos, Nina Gubina, Reinald Pamplona, Tommi Rantapero, Matti Nykter, Ihor S. Yurkevych, Filippo Scialò, Mariona Jové, Alba Naudí
Publikováno v:
Repositorio Abierto de la UdL
Universitad de Lleida
Digital.CSIC. Repositorio Institucional del CSIC
instname
Universitad de Lleida
Digital.CSIC. Repositorio Institucional del CSIC
instname
Aging is a multifactorial process which affects all animals. Aging as a result of damage accumulation is the most accepted explanation but the proximal causes remain to be elucidated. There is also evidence indicating that aging has an important gene
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8549 (2010)
BackgroundA point mutation in the Drosophila gene technical knockout (tko), encoding mitoribosomal protein S12, was previously shown to cause a phenotype of respiratory chain deficiency, developmental delay, and neurological abnormalities similar to
Externí odkaz:
https://doaj.org/article/ffb2ebf584b74dfb90c7d31140c09322
Autor:
Andrea Di Francesco, Guillermo López-Lluch, Rafael de Cabo, Ignacio Guerra, Antonia Ribes, Sandra Y. Prieto-Soler, Ana Cortés, Luis Vazquez-Fonseca, Eduardo Domínguez-del-Toro, Cristina Jou, Miguel A. Aon, Sandra Jackson, Rafael Artuch, Zoltan Horvath, Juan Carlos Rodríguez-Aguilera, Jochen Schaefer, Ana Sánchez-Cuesta, Michel Bernier, Plácido Navas, María V. Cascajo, Daniel J. M. Fernández-Ayala, Gloria Brea-Calvo, Cristiane Matté, Emilio Siendones, Carlos Santos-Ocaña, Ignacio Navas-Enamorado, Purificación Gutierrez-Rios, Juan Diego Hernández-Camacho, Leonardo Salviati, Mercedes Casado
Publikováno v:
Journal of Clinical Medicine
Volume 8
Issue 9
Digital.CSIC. Repositorio Institucional del CSIC
instname
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Journal of Clinical Medicine, Vol 8, Iss 9, p 1374 (2019)
Volume 8
Issue 9
Digital.CSIC. Repositorio Institucional del CSIC
instname
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Journal of Clinical Medicine, Vol 8, Iss 9, p 1374 (2019)
© 2019 by the authors.
Fatty acids and glucose are the main bioenergetic substrates in mammals. Impairment of mitochondrial fatty acid oxidation causes mitochondrial myopathy leading to decreased physical performance. Here, we report that haplo
Fatty acids and glucose are the main bioenergetic substrates in mammals. Impairment of mitochondrial fatty acid oxidation causes mitochondrial myopathy leading to decreased physical performance. Here, we report that haplo