Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Daniel J. Lippincott"'
Autor:
Hongwei Yang, Evan B. Landstrom, Ning Ye, Bruce H. Lipshutz, Corinne Durano, Michael Parmentier, Margery Cortes-Clerget, Bin Wu, Daniel J. Lippincott, Min Shi, Klaus Buescher, Martin Andersson, Fabrice Gallou, Robert Schreiber
Publikováno v:
Lippincott, D J, Landstrom, E, Cortes-Clerget, M, Lipshutz, B H, Buescher, K, Schreiber, R, Durano, C, Parmentier, M, Ye, N, Wu, B, Shi, M, Yang, H, Andersson, M & Gallou, F 2020, ' Surfactant Technology: With New Rules, Designing New Sequences Is Required! ', Organic Process Research & Development, vol. 24, no. 5, pp. 841–849 . https://doi.org/10.1021/acs.oprd.9b00454
With a growing toolbox of surfactant-mediated chemistry in water and an increased number of scaled-up transformations has come tremendous learning [for example, see: Lipshutz, B. H.; et al. The Hydrophobic Effect Applied to Organic Synthesis: Recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74f77368197605c04a10097bbd71968
https://doi.org/10.1021/acs.oprd.9b00454
https://doi.org/10.1021/acs.oprd.9b00454
Autor:
Bruno Melillo, Jun Park, Amos B. Smith, Sharon M. Kirk, Xiangqin Li, Hung-Ching Chen, Daniel J. Lippincott, Junhua Chen
Publikováno v:
Org Process Res Dev
We report here the development and optimization of a process synthesis for the HIV-1 entry inhibitor BNM-III-170 bis-TFA salt (1). The synthesis features a dynamic-kinetic resolution (DKR) to establish the initial stereogenicity. By taking advantage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4660fb4958cd43cbc28897782a66b7
https://doi.org/10.1021/acs.oprd.9b00353
https://doi.org/10.1021/acs.oprd.9b00353
Autor:
Felipe C. Braga, Daniel J. Lippincott, Fabrice Gallou, Bruce H. Lipshutz, Bingchun Zhu, Farbod A. Moghadam, Nicholas R. Lee
Publikováno v:
Organic letters. 22(13)
Palladium-catalyzed allylic substitution, or "Tsuji-Trost" reactions, can be run under micellar catalysis conditions featuring not only chemistry in water but also numerous combinations of reaction partners that require low levels of palladium, typic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c5a1f6429905688c5c546cdfea71519
https://pubmed.ncbi.nlm.nih.gov/32551706
https://pubmed.ncbi.nlm.nih.gov/32551706
Autor:
Robert Lipski, Daniel J Lippincott, Brittany C Durden, Anne R Kaplan, Hilary E Keiser, Jung-Ho Park, Aime A Levesque
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42615 (2012)
DNA damage induced by the topoisomerase I inhibitor SN38 activates cell cycle checkpoints which promote cell cycle arrest. This arrest can be abrogated in p53-defective cells by the Chk1 inhibitor 7-hydroxystaurosporine (UCN-01). Previously, we compa
Externí odkaz:
https://doaj.org/article/9bb815b69d5f4ab8b85027c93c2a69c0
Publikováno v:
Organic Letters. 20:5094-5097
A copper-catalyzed oxidative cleavage of electron-rich olefins into their corresponding carbonyl derivatives is described as an alternative to ozonolysis. The scope includes various precursors to aryl ketone derivatives, as well as oxidations of enol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6f99780134ef7dbf2e19a7ff2dc9aa2
https://doi.org/10.1021/acs.orglett.8b01883
https://doi.org/10.1021/acs.orglett.8b01883
Autor:
Margery Cortes-Clerget, Nicholas R. Lee, Fabrice Gallou, Farbod A. Moghadam, Daniel J. Lippincott, Bruce H. Lipshutz, Alex B. Wood, Haobo Pang
Publikováno v:
ChemSusChem. 12(13)
Several types of reduction reactions in organic synthesis are performed under aqueous micellar-catalysis conditions (in water at ambient temperature), which produce a significant volume of foam owing to the combination of the surfactant and the prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8ec99f36c5fddd4adb922c6cbedcd42
https://pubmed.ncbi.nlm.nih.gov/30889298
https://pubmed.ncbi.nlm.nih.gov/30889298
Publikováno v:
Angewandte Chemie International Edition. 56:847-850
A mild method for the synthesis of highly functionalized [3]-[6]dendralenes is reported, representing a general strategy to diversely substituted higher homologues of the dendralenes. The methodology utilizes allenoates bearing various substitution p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a62b60f8a531b757a94d75fca84e27f
https://doi.org/10.1002/anie.201609636
https://doi.org/10.1002/anie.201609636
Autor:
Bruce H. Lipshutz, Michael R. Maser, Daniel J. Lippincott, Fabrice Gallou, Roscoe T. H. Linstadt
Publikováno v:
Organic letters. 20(16)
An environmentally responsible, mild method for the synthesis of functionalized 1,3-butadienes is presented. It utilizes allenic esters of varying substitution patterns, as well as a wide range of boron-based nucleophiles under palladium catalysis, g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed70493f98054056b0e4a310cfdd60b5
https://pubmed.ncbi.nlm.nih.gov/30080419
https://pubmed.ncbi.nlm.nih.gov/30080419
Autor:
Daniel J. Lippincott, Bruce H. Lipshutz, Roscoe T. H. Linstadt, Carl A. Peterson, Carina I. Jette
Publikováno v:
Angewandte Chemie. 126:4243-4247
Micellar catalysis enables copper-catalyzed silylcupration of a variety of electron-deficient alkynes, thereby providing access to isomerically pure E- or Z-β-silyl-substituted carbonyl derivatives. These reactions take place in minutes, afford high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbf0a632a7754a0021419da546bce2f
https://doi.org/10.1002/ange.201311035
https://doi.org/10.1002/ange.201311035
Publikováno v:
ChemInform. 46
The gold catalyst is highly effective in achieving the asymmetric intramolecular hydrocarboxylation of allenes in aqueous micellar reaction medium.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cda0112e0cf1d077163b4a7c59ffb824
https://doi.org/10.1002/chin.201511136
https://doi.org/10.1002/chin.201511136