Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Daniel J. Kelly"'
Autor:
Leandra S. Baptista, Constance Porrini, Gabriela S. Kronemberger, Daniel J. Kelly, Cecile M. Perrault
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/1062cecbec9b4223955d9d04f4a6a914
Publikováno v:
Materials Today Bio, Vol 20, Iss , Pp 100624- (2023)
Decellularized extracellular matrix (dECM) has emerged as a promising biomaterial in the fields of tissue engineering and regenerative medicine due to its ability to provide specific biochemical and biophysical cues supportive of the regeneration of
Externí odkaz:
https://doaj.org/article/0966bb95df474161ac9ae371a3ed23cf
Autor:
Tanya J. Levingstone, Eamon J. Sheehy, Conor J. Moran, Gráinne M. Cunniffe, Pedro J. Diaz Payno, Robert T. Brady, Henrique V. Almeida, Simon F. Carroll, John M. O’Byrne, Daniel J. Kelly, Pieter AJ. Brama, Fergal J. O’ Brien
Publikováno v:
Biomaterials and Biosystems, Vol 8, Iss , Pp 100066- (2022)
Cartilage has poor regenerative capacity and thus damage to the joint surfaces presents a major clinical challenge. Recent research has focussed on the development of tissue-engineered and cell-based approaches for the treatment of cartilage and oste
Externí odkaz:
https://doaj.org/article/8d0816a7cda94001a054287d371b4782
Autor:
David C. Browe, Ross Burdis, Pedro J. Díaz-Payno, Fiona E. Freeman, Jessica M. Nulty, Conor T. Buckley, Pieter A.J. Brama, Daniel J. Kelly
Publikováno v:
Materials Today Bio, Vol 16, Iss , Pp 100343- (2022)
Articular cartilage defects fail to heal spontaneously, typically progressing to osteoarthritis. Bone marrow stimulation techniques such as microfracture (MFX) are the current surgical standard of care; however MFX typically produces an inferior fibr
Externí odkaz:
https://doaj.org/article/87c2e54468a044dcbcd11fc8165ed03b
Autor:
Leandra S. Baptista, Constance Porrini, Gabriela S. Kronemberger, Daniel J. Kelly, Cecile M. Perrault
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Medicine today faces the combined challenge of an increasing number of untreatable diseases and fewer drugs reaching the clinic. While pharmaceutical companies have increased the number of drugs in early development and entering phase I of clinical t
Externí odkaz:
https://doaj.org/article/8778fe29c861447fbdc0d3c9c27e5768
Autor:
Selcan Guler, Kian Eichholz, Farhad Chariyev-Prinz, Pierluca Pitacco, Halil Murat Aydin, Daniel J. Kelly, İbrahim Vargel
Publikováno v:
Bioengineering, Vol 10, Iss 1, p 30 (2022)
The microarchitecture of bone tissue engineering (BTE) scaffolds has been shown to have a direct effect on the osteogenesis of mesenchymal stem cells (MSCs) and bone tissue regeneration. Poly(glycerol sebacate) (PGS) is a promising polymer that can b
Externí odkaz:
https://doaj.org/article/db6586b3d1694c4a93f01d6c8cae9678
Publikováno v:
Materials Today Bio, Vol 12, Iss , Pp 100173- (2021)
Successful repair of osteochondral defects is challenging, due in part to their complex gradient nature. Tissue engineering approaches have shown promise with the development of layered scaffolds that aim to promote cartilage and bone regeneration wi
Externí odkaz:
https://doaj.org/article/5b3775df908249179d74d1535cd26b1b
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Bone tissue engineering (TE) has the potential to transform the treatment of challenging musculoskeletal pathologies. To date, clinical translation of many traditional TE strategies has been impaired by poor vascularisation of the implant. Addressing
Externí odkaz:
https://doaj.org/article/afabc88ac4a5490b9e27e2578701a228
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Understanding how the local cellular environment influences cell metabolism, phenotype and matrix synthesis is crucial to engineering functional tissue grafts of a clinically relevant scale. The objective of this study was to investigate how the loca
Externí odkaz:
https://doaj.org/article/47db6bb44e9e4dc793978d049a6d6379
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1621 (2022)
Negative foreign body responses following the in vivo implantation of bioprinted implants motivate the development of novel bioinks which can rapidly degrade with the formation of functional tissue, whilst still maintaining desired shapes post-printi
Externí odkaz:
https://doaj.org/article/ba74bc0719494b269d693c40540fa9cb