Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Daniel J. Kass"'
Autor:
Rohit Aggarwal, Chester V. Oddis, Daniel I. Sullivan, Siamak Moghadam-Kia, Didem Saygin, Daniel J. Kass, Diane C. Koontz, Peide Li, Craig S. Conoscenti, Amy L. Olson, on behalf of the MINT investigators
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background The Myositis Interstitial Lung Disease Nintedanib Trial (MINT) is a hybrid trial, which is enrolling patients both at local sites and remotely via a decentralised site. The trial will investigate the efficacy and safety of ninteda
Externí odkaz:
https://doaj.org/article/dfc7bd4701534e8db469db607fa23e05
Autor:
Tejaswini Kulkarni, Gerard J. Criner, Daniel J. Kass, Ivan O. Rosas, Mary Beth Scholand, Daniel F. Dilling, Ross Summer, Steven R. Duncan
Publikováno v:
BMC Pulmonary Medicine, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF) affect a significant proportion of patients with IPF. There are limited data to inform therapeutic strategies for AE-IPF, despite its high mortality. We discuss the rat
Externí odkaz:
https://doaj.org/article/b6ff537476e64303be636132d7784808
Autor:
Raju S. R. Adduri, Kai Cai, Karen Velasco‐Alzate, Ravikiran Vasireddy, Jeffrey W. Miller, Sergio Poli deFrías, Fernando Poli deFrías, Yasushi Horimasu, Hiroshi Iwamoto, Noboru Hattori, Yingze Zhang, Kevin F. Gibson, Anoop K. Pal, Zhe Chen, Daniela Nicastro, Li Li, Sujith Cherian, Lynette M. Sholl, Sreerama Shetty, Harrison Ndetan, Anthony H. Maeda, Maria A. Planchart Ferretto, Gary M. Hunninghake, David A. Schwartz, Daniel J. Kass, Ivan O. Rosas, Nagarjun V. Konduru
Publikováno v:
Journal of Extracellular Biology, Vol 2, Iss 7, Pp n/a-n/a (2023)
Abstract High‐resolution computed tomography (HRCT) imaging is critical for diagnostic evaluation of Idiopathic Pulmonary Fibrosis (IPF). However, several other interstitial lung diseases (ILDs) often exhibit radiologic pattern similar to IPF on HR
Externí odkaz:
https://doaj.org/article/e69d46450fac495195f0f07fb72f96a3
Autor:
Gillian C. Goobie, Christopher J. Ryerson, Kerri A. Johannson, Spencer Keil, Erin Schikowski, Nasreen Khalil, Veronica Marcoux, Deborah Assayag, Hélène Manganas, Jolene H. Fisher, Martin R.J. Kolb, Xiaoping Chen, Kevin F. Gibson, Daniel J. Kass, Yingze Zhang, Kathleen O. Lindell, S. Mehdi Nouraie
Publikováno v:
ERJ Open Research, Vol 8, Iss 4 (2022)
Background This multicentre, international, prospective cohort study evaluated whether patients with pulmonary sarcoidosis living in neighbourhoods with greater material and social disadvantage experience worse clinical outcomes. Methods The area dep
Externí odkaz:
https://doaj.org/article/7c20d9abe6ee4610b0d2444e60d3a167
Publikováno v:
Pulmonary Therapy, Vol 6, Iss 1, Pp 35-46 (2020)
Abstract Idiopathic pulmonary fibrosis (IPF) is a progressive fibrotic lung disease with a median survival of 3–4 years from time of initial diagnosis, similar to the time course of many malignancies. A hallmark of IPF is its unpredictable disease
Externí odkaz:
https://doaj.org/article/e09e294f63ab456989c3fd9644e8d9cd
Autor:
Qinmao Ye, Sarah J. Taleb, Heather Wang, Narasimham L. Parinandi, Daniel J. Kass, Mauricio Rojas, Cankun Wang, Qin Ma, Jing Zhao, Yutong Zhao
Publikováno v:
Biomolecules, Vol 12, Iss 10, p 1531 (2022)
Idiopathic pulmonary fibrosis (IPF) is a fatal chronic lung disease. Heme oxygenase-1 (HMOX1/HO-1) is an enzyme that catalyzes the degradation of heme. The role of HO-1 in the pathogenesis of IPF has been studied; however, the molecular regulation of
Externí odkaz:
https://doaj.org/article/dd9af890654c459da70b1bf1e4f85239
Autor:
Daniel I. Sullivan, Mao Jiang, Angela M. Hinchie, Mark G. Roth, Harinath Bahudhanapati, Mehdi Nouraie, Jie Liu, John F. McDyer, Rama K. Mallampalli, Yingze Zhang, Daniel J. Kass, Toren Finkel, Jonathan K. Alder
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Cellular senescence due to telomere dysfunction has been hypothesized to play a role in age-associated diseases including idiopathic pulmonary fibrosis (IPF). It has been postulated that paracrine mediators originating from senescent alveolar epithel
Externí odkaz:
https://doaj.org/article/0cd55ce4a07c4a47bf85b736b8a2dc7f
Autor:
Ting-Yun Chen, Xiaoyun Li, Gillian C. Goobie, Ching-Hsia Hung, Tin-Kan Hung, Kyle Hamilton, Harinath Bahudhanapati, Jiangning Tan, Daniel J. Kass, Yingze Zhang
Publikováno v:
PLoS ONE, Vol 16, Iss 12 (2021)
Relaxin/insulin-like family peptide receptor 1 (RXFP1) mediates relaxin’s antifibrotic effects and has reduced expression in the lung and skin of patients with fibrotic interstitial lung disease (fILD) including idiopathic pulmonary fibrosis (IPF)
Externí odkaz:
https://doaj.org/article/a278f1d82dd0444cb398fea8e2fc65e6
Autor:
Ting‐Yun Chen, Xiaoyun Li, Ching‐Hsia Hung, Harinath Bahudhanapati, Jiangning Tan, Daniel J. Kass, Yingze Zhang
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 4, Pp n/a-n/a (2020)
Abstract Background Relaxin/relaxin family peptide receptor 1 (RXFP1) signaling is important for both normal physiology and disease. Strong preclinical evidence supports relaxin as a potent antifibrotic molecule. However, relaxin‐based therapy fail
Externí odkaz:
https://doaj.org/article/96e610b58a7c410ab9c85e4615ad23d7
Autor:
Ferhan Tuncer, Melissa Bulik, John Villandre, Travis Lear, Yanwen Chen, Beyza Tuncer, Daniel J. Kass, Eleanor Valenzi, Christina Morse, John Sembrat, Robert Lafyatis, Bill Chen, John Evankovich
Publikováno v:
American journal of physiology. Lung cellular and molecular physiology. 323(4)
Accumulation of excessive extracellular matrix (ECM) components from lung fibroblasts is a feature of systemic sclerosis-associated interstitial lung disease (SSc-ILD), and there is increasing evidence that innate immune signaling pathways contribute