Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Daniel J. Greenwood"'
Autor:
Pierre Santucci, Daniel J. Greenwood, Antony Fearns, Kai Chen, Haibo Jiang, Maximiliano G. Gutierrez
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Effective chemotherapies against tuberculosis must kill the pathogen’s intracellular population. Here, Santucci et al. show that bacterial localisation within human macrophages impact pyrazinamide (PZA) accumulation and efficacy, and that combinati
Externí odkaz:
https://doaj.org/article/f78b658f091740388c9796a7a5393a12
Autor:
Michele D. Larson, Edward P. Levri, Snehalata V. Huzurbazar, Daniel J. Greenwood, Kara L. Wise, Amy C. Krist, Daniel de Paiva Silva
Publikováno v:
PLoS ONE, Vol 15, Iss 10 (2020)
The dilution effect can occur by a range of mechanisms and results in reduced parasite prevalence in host taxa. In invaded ecosystems, the dilution effect can benefit native species if non-native species, acting as resistant or less competent hosts,
Externí odkaz:
https://doaj.org/article/d5e3a471559949838b30562bbd937625
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3000879 (2020)
Correlative light, electron, and ion microscopy (CLEIM) offers huge potential to track the intracellular fate of antibiotics, with organelle-level resolution. However, a correlative approach that enables subcellular antibiotic visualisation in pathog
Externí odkaz:
https://doaj.org/article/d4d0c9db78524b23a0be687787c9ab2f
Publikováno v:
Biological Invasions. 22:363-378
Population dynamics of invasive species can exhibit rapid population growth followed by rapid decline. Populations of Potamopyrgus antipodarum, an invasive gastropod native to New Zealand, can follow this pattern, but potential mechanisms are unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99cd5f759c9df6bed4ecf1f28cfd1f19
https://doi.org/10.1007/s10530-019-02093-8
https://doi.org/10.1007/s10530-019-02093-8
Autor:
Luiz Pedro S. de Carvalho, Steven Howell, Mercedes Monteleone, Stuart Horswell, Brian C. VanderVen, Warwick J. Britton, Ambrosius P. Snijders, Agnese Serafini, Acely Garza-Garcia, Lendl Tan, Minh-Duy Phan, Mark A. Schembri, Maximiliano G. Gutierrez, Christine R Montague, Nicholas P. West, Deborah M. Hunt, Daniel J. Greenwood
Publikováno v:
Molecular Microbiology
Summary Bacterial nutrition is an essential aspect of host–pathogen interaction. For the intracellular pathogen Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis in humans, fatty acids derived from lipid droplets are considered
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164641ab7aad65dcd47e554e5658fbce
https://doi.org/10.1111/mmi.14362
https://doi.org/10.1111/mmi.14362
Autor:
Haibo Jiang, Antony Fearns, Pierre Santucci, Daniel J. Greenwood, Maximiliano G. Gutierrez, Kai Chen
To be effective, chemotherapy against tuberculosis (TB) must kill the intracellular population ofMycobacterium tuberculosis(Mtb). However, how host cell environments affect antibiotic accumulation and efficacy remains elusive. Pyrazinamide (PZA) is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a2d860f7f6114d9bc2da460eb7b2ee4
https://doi.org/10.1101/2020.11.25.398636
https://doi.org/10.1101/2020.11.25.398636
Autor:
Edward P. Levri, Kara L. Wise, Snehalata Huzurbazar, Amy C. Krist, Michele D. Larson, Daniel J. Greenwood
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 10, p e0239762 (2020)
PLoS ONE, Vol 15, Iss 10, p e0239762 (2020)
The dilution effect can occur by a range of mechanisms and results in reduced parasite prevalence in host taxa. In invaded ecosystems, the dilution effect can benefit native species if non-native species, acting as resistant or less competent hosts,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2330f4b79afcbdec4183556e10c4b81
http://europepmc.org/articles/PMC7529281
http://europepmc.org/articles/PMC7529281
Autor:
Christophe J. Queval, Lucy M. Collinson, Rachel P. J. Lai, Matthew R. G. Russell, Daniel J. Greenwood, Thomas R. Lerner, Robert J. Wilkinson, Antony Fearns, Maximiliano G. Gutierrez
Publikováno v:
JCI Insight
The ability of Mycobacterium tuberculosis to form serpentine cords is intrinsically related to its virulence, but specifically how M. tuberculosis cording contributes to pathogenesis remains obscure. Here, we show that several M. tuberculosis clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5495f5d18aa67863aa4960ea9873069b
https://pubmed.ncbi.nlm.nih.gov/32369443
https://pubmed.ncbi.nlm.nih.gov/32369443
Autor:
Marissa A. Dyck, Katelyn Larkin, Amy C. Krist, Laura Bankers, Michele D. Larson, Daniel J. Greenwood, Maurine Neiman
Publikováno v:
Oecologia. 185:595-605
We investigated whether previously documented variation among populations in availability of dietary phosphorus (P) is linked to heterogeneity in growth rate of the New Zealand freshwater snail Potamopyrgus antipodarum on a P-limited diet. We chose t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76d07303ffcbfb09f4283a27005e8efe
https://doi.org/10.1007/s00442-017-3983-4
https://doi.org/10.1007/s00442-017-3983-4
Autor:
Urska Repnik, Martin L. Jones, Lucy M. Collinson, Maximiliano G. Gutierrez, Gareth Griffiths, Matthew R. G. Russell, Thomas R. Lerner, Daniel J. Greenwood, Sophie Borel, Susanne Herbst
Publikováno v:
The Journal of Cell Biology
Mycobacterium tuberculosis triggers macrophage cell death by necrosis, but it is unclear how this affects bacterial replication. Lerner et al. show that this pathogen replicates within necrotic human macrophages before disseminating to other cells up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0581db441d8a882e9e2be2d40d93056e
http://europepmc.org/articles/PMC5350509
http://europepmc.org/articles/PMC5350509