Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daniel J. Grau"'
Autor:
Clifford J. Tabin, Sharmistha Kundu, Sharon K. Marr, Ruslan I. Sadreyev, Peggy I. Wang, Andrej J. Savol, Matthew G. Schwartz, Daniel J. Grau, Patrick Schorderet, Robert E. Kingston, Mei Sheng Lau
Publikováno v:
Science. 355:1081-1084
Polycomb group gene silencing Histone proteins wrap around DNA to form nucleosomes that package metazoan DNA into the nucleus. Chromatin compaction is also believed to be critical for the repression of homeotic genes by the Polycomb repressive comple
Autor:
Marlene Holder, Daniel J. Grau, Jenny Zhang, Chul Hwan Lee, Rais Ahmad Ganai, Karim-Jean Armache, Danny Reinberg, Ricardo Saldaña-Meyer, Miao Wang, Marc-Werner Dobenecker
The maintenance of gene expression patterns during metazoan development is carried out, in part, by the actions of the Polycomb Repressive Complex 2 (PRC2). PRC2 catalyzes mono-, di-and trimethylation of histone H3 at lysine 27 (H3K27), with H3K27me2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10657744273673d4a743a2e12b34fed7
Autor:
Daniel J. Grau, Kavitha Sarma, Jing Zhao, Ji-Joon Song, Mark L. Borowsky, Yuya Ogawa, Robert E. Kingston, Johnny T. Kung, Toshiro K. Ohsumi, Jeannie T. Lee
Publikováno v:
Molecular Cell. 40:939-953
Polycomb proteins play essential roles in stem cell renewal and human disease. Recent studies of HOX genes and X-inactivation have provided evidence for RNA cofactors in Polycomb repressive complex 2 (PRC2). Here, we develop a RIP-seq method to captu
Publikováno v:
Nucleic Acids Research
Polycomb-group response elements (PREs) are DNA elements through which the Polycomb-group (PcG) of transcriptional repressors act. Many of the PcG proteins are associated with two protein complexes that repress gene expression by modifying chromatin.
Autor:
Daniel J. Grau, Robert E. Kingston, Jonathan H. Dennis, William Stafford Noble, Denis Avey, Shobhit Gupta, Brittany S. Sexton, Jinfeng Zhang, Fanxiu Zhu, Daniel L. Vera, Justin A. Fincher, Senthil Girimurugan, Eric Chicken, Brooke R. Druliner, Mark L. Borowsky
Publikováno v:
Genome research. 24(2)
Nucleosome occupancy plays a key role in regulating access to eukaryotic genomes. Although various chromatin regulatory complexes are known to regulate nucleosome occupancy, the role of DNA sequence in this regulation remains unclear, particularly in
Autor:
Karim-Jean Armache, Christopher P. Davis, Daniel J. Grau, Robert E. Kingston, Jason A. West, Matthew D. Simon, Joseph D. Garlick
Publikováno v:
The FASEB Journal. 27
Compaction of chromatin by diverse Polycomb group proteins requires localized regions of high charge
Autor:
Robert E. Kingston, Nicole J. Francis, Brad Chapman, Joseph D. Garlick, Daniel J. Grau, Mark L. Borowsky
Publikováno v:
Genesdevelopment. 25(20)
Polycomb group (PcG) proteins are required for the epigenetic maintenance of developmental genes in a silent state. Proteins in the Polycomb-repressive complex 1 (PRC1) class of the PcG are conserved from flies to humans and inhibit transcription. On
Publikováno v:
Cold Spring Harbor symposia on quantitative biology. 75
Silencing of homeotic genes requires the Polycomb repressive complex 1 (PRC1) family of protein complexes, which are composed of Polycomb-group (PcG) proteins and frequently include other subunits. We discuss here two aspects of PRC1 that might contr
Autor:
Lau, Mei Sheng, Schwartz, Matthew G., Kundu, Sharmistha, Savol, Andrej J., Wang, Peggy I., Marr, Sharon K., Grau, Daniel J., Schorderet, Patrick, Sadreyev, Ruslan I., Tabin, Clifford J., Kingston, Robert E.
Publikováno v:
Sciencemag.org; 3/10/2017, p1081-1084, 4p
Publikováno v:
Nucleic Acids Research; Sep2005, Vol. 33 Issue 16, p5181-5189, 9p