Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Daniel J. Fitzgerald"'
Autor:
Kapil Gupta, Christine Tölzer, Duygu Sari-Ak, Daniel J. Fitzgerald, Christiane Schaffitzel, Imre Berger
Publikováno v:
Viruses, Vol 11, Iss 3, p 198 (2019)
The baculovirus/insect cell system (BICS) is widely used in academia and industry to produce eukaryotic proteins for many applications, ranging from structure analysis to drug screening and the provision of protein biologics and therapeutics. Multi-p
Externí odkaz:
https://doaj.org/article/00b05f6214f9471b869ead3e2a48258a
Autor:
Deborah K. Shoemark, A. Sofia F. Oliveira, Frederic Garzoni, Maia Kavanagh Williamson, Kapil Gupta, Joachim P. Spatz, K.N. Sathish Yadav, Ufuk Borucu, Imre Berger, Andrew D. Davidson, Christine Toelzer, Adrian J. Mulholland, Daniel J. Fitzgerald, David A. Matthews, Abdulaziz Almuqrin, Christiane Schaffitzel, Oskar Staufer
As the global burden of SARS-CoV-2 infections escalates, so does the evolution of viral variants which is of particular concern due to their potential for increased transmissibility and pathology. In addition to this entrenched variant diversity in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::986607fc6ad12c797c4d989da7970a1b
https://doi.org/10.1101/2021.05.11.443384
https://doi.org/10.1101/2021.05.11.443384
Autor:
Daniel J. Fitzgerald, Frederic Garzoni, Christiane Schaffitzel, Duygu Sari-Ak, Kapil Gupta, Joshua C. Bufton, Imre Berger
Publikováno v:
Sari-Ak, D, Bufton, J C, Gupta, K, Garzoni, F, Fitzgerald, D J, Berger-Schaffitzel, C H & Berger, I 2021, ' VLP-factory™ and ADDomer © : Self-assembling Virus-Like Particle (VLP) technologies for multiple protein and peptide epitope display ', Current Protocols, vol. 1, no. 3, e55 . https://doi.org/10.1002/cpz1.55
Virus-like particles (VLPs) play a prominent role in vaccination as safe and highly versatile alternatives to attenuated or inactivated viruses or subunit vaccines. We present here two innovations, VLP-factory™ and ADDomer© , for creating VLPs dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6345d72b6d2db8471bdfc57adc6d042e
https://doi.org/10.1002/cpz1.55
https://doi.org/10.1002/cpz1.55
Autor:
Christine Toelzer, Imre Berger, Frederic Garzoni, Maia Kavanagh Williamson, Julien Capin, Oskar Staufer, Joachim P. Spatz, Andrew D. Davidson, Kapil Gupta, Deborah K. Shoemark, Daniel J. Fitzgerald, Adrian J. Mulholland, Rachel Milligan, Ufuk Borucu, Christiane Schaffitzel, K.N. Sathish Yadav
Publikováno v:
Science
Toelzer, C, Gupta, K, Yadav, S K N, Borucu, U, Davidson, A D, Kavanagh Williamson, M, Shoemark, D K, Garzoni, F, Staufer, O, Milligan, R, Capin, J, Mulholland, A J, Berger, I & Schaffitzel, C 2020, ' Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein ', Science, vol. 370, no. 6517, eabd3255 . https://doi.org/10.1126/science.abd3255
Science (New York, N.y.)
Toelzer, C, Gupta, K, Yadav, S K N, Borucu, U, Davidson, A D, Kavanagh Williamson, M, Shoemark, D K, Garzoni, F, Staufer, O, Milligan, R, Capin, J, Mulholland, A J, Berger, I & Schaffitzel, C 2020, ' Free fatty acid binding pocket in the locked structure of SARS-CoV-2 spike protein ', Science, vol. 370, no. 6517, eabd3255 . https://doi.org/10.1126/science.abd3255
Science (New York, N.y.)
Locking down the SARS-CoV-2 spike Many efforts to develop therapies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are focused on the spike (S) protein trimer that binds to the host receptor. Structures of trimeric S protein sho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900a1a0a17e2248e7197013081ee0f35
https://pubmed.ncbi.nlm.nih.gov/32958580/
https://pubmed.ncbi.nlm.nih.gov/32958580/
Autor:
Joachim P. Spatz, Christine Toelzer, Frederic Garzoni, Daniel J. Fitzgerald, Oskar Staufer, Christiane Schaffitzel, Julien Capin, Imre Berger, Ufuk Borucu, Kapil Gupta, K.N. Sathish Yadav
COVID-19, caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), represents a global crisis. Key to SARS-CoV-2 therapeutic development is unraveling the mechanisms driving high infectivity, broad tissue tropism and severe pathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56ab0cd9112791ffb1628a81166e70a6
https://doi.org/10.1101/2020.06.18.158584
https://doi.org/10.1101/2020.06.18.158584
Autor:
Duygu, Sari-Ak, Shervin, Bahrami, Magdalena J, Laska, Petra, Drncova, Daniel J, Fitzgerald, Christiane, Schaffitzel, Frederic, Garzoni, Imre, Berger
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2025
Baculovirus-based expression of proteins in insect cell cultures has emerged as a powerful technology to produce complex protein biologics for many applications ranging from multiprotein complex structural biology to manufacturing of therapeutic prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e563d1b7004f6c3cdb2326810239f37f
https://pubmed.ncbi.nlm.nih.gov/31267455
https://pubmed.ncbi.nlm.nih.gov/31267455
Autor:
Imre Berger, Magdalena Janina Laska, Daniel J. Fitzgerald, Frederic Garzoni, Petra Drncova, Duygu Sari-Ak, Christiane Schaffitzel, Shervin Bahrami
Publikováno v:
Methods in Molecular Biology ISBN: 9781493996230
Sari-Ak, D, Bahrami, S, Laska, M, Drncova, P, Fitzgerald, D J, Berger-Schaffitzel, C, Garzoni, F & Berger, I 2019, High-Throughput Production of Influenza Virus-Like Particle (VLP) Array by Using VLP-factory™, a MultiBac Baculoviral Genome Customized for Enveloped VLP Expression . in R Vincentelli (ed.), High-Throughput Protein Production and Purification : Methods and Protocols . Methods in Molecular Biology, vol. 2025, Humana Press, pp. 213-226 . https://doi.org/10.1007/978-1-4939-9624-7_10
Sari-Ak, D, Bahrami, S, Laska, M J, Drncova, P, Fitzgerald, D J, Schaffitzel, C, Garzoni, F & Berger, I 2019, High-Throughput Production of Influenza Virus-Like Particle (VLP) Array by Using VLP-factory™, a MultiBac Baculoviral Genome Customized for Enveloped VLP Expression . in R Vincentelli (ed.), High-Throughput Protein Production and Purification : Methods and Protocols . vol. 2025, Humana Press, Methods in molecular biology (Clifton, N.J.), pp. 213-226 . https://doi.org/10.1007/978-1-4939-9624-7_10
Sari-Ak, D, Bahrami, S, Laska, M, Drncova, P, Fitzgerald, D J, Berger-Schaffitzel, C, Garzoni, F & Berger, I 2019, High-Throughput Production of Influenza Virus-Like Particle (VLP) Array by Using VLP-factory™, a MultiBac Baculoviral Genome Customized for Enveloped VLP Expression . in R Vincentelli (ed.), High-Throughput Protein Production and Purification : Methods and Protocols . Methods in Molecular Biology, vol. 2025, Humana Press, pp. 213-226 . https://doi.org/10.1007/978-1-4939-9624-7_10
Sari-Ak, D, Bahrami, S, Laska, M J, Drncova, P, Fitzgerald, D J, Schaffitzel, C, Garzoni, F & Berger, I 2019, High-Throughput Production of Influenza Virus-Like Particle (VLP) Array by Using VLP-factory™, a MultiBac Baculoviral Genome Customized for Enveloped VLP Expression . in R Vincentelli (ed.), High-Throughput Protein Production and Purification : Methods and Protocols . vol. 2025, Humana Press, Methods in molecular biology (Clifton, N.J.), pp. 213-226 . https://doi.org/10.1007/978-1-4939-9624-7_10
Baculovirus-based expression of proteins in insect cell cultures has emerged as a powerful technology to produce complex protein biologics for many applications ranging from multiprotein complex structural biology to manufacturing of therapeutic prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1a5e061533581221fec7f62719f110b
https://doi.org/10.1007/978-1-4939-9624-7_10
https://doi.org/10.1007/978-1-4939-9624-7_10
Autor:
Ryan L. Truby, Jennifer A. Lewis, Michael Wehner, Bobak Mosadegh, Daniel J. Fitzgerald, George M. Whitesides, Robert J. Wood
Publikováno v:
Nature. 536:451-455
An untethered, entirely soft robot is designed to operate autonomously by combining microfluidic logic and hydrogen peroxide as an on-board fuel supply. Soft robotics have so far necessarily included some 'hard' or metallic elements, in particular in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1ceb706ef4050b63a98e37b6ec31e3
https://doi.org/10.1038/nature19100
https://doi.org/10.1038/nature19100
Autor:
Valentin Gordeliy, Evelina Edelweiss, Imre Berger, Deepak B. Thimiri Govinda Raj, Lakshmi Sumitra Vijayachandran, Daniel J. Fitzgerald, Josef Maier, Kapil Gupta
Publikováno v:
Bioengineered
Bioengineered, 2013, 4 (5), pp.279-87. ⟨10.4161/bioe.22966⟩
Bioengineered, 2013, 4 (5), pp.279-87. ⟨10.4161/bioe.22966⟩
International audience; Most essential activities in eukaryotic cells are catalyzed by large multiprotein assemblies containing up to ten or more interlocking subunits. The vast majority of these protein complexes are not easily accessible for high r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29eab178cc538ff56f30aab2495b7bd
https://doi.org/10.4161/bioe.22966
https://doi.org/10.4161/bioe.22966
Autor:
Daniel J, Fitzgerald, Paul J, Renick, Emma C, Forrest, Shannon P, Tetens, David N, Earnest, Jillian, McMillan, Brett M, Kiedaisch, Lei, Shi, Eric D, Roche
Publikováno v:
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 25(1)
Examination of clinical samples indicates bacterial biofilms are present in the majority of chronic wounds, and substantial evidence suggests biofilms contribute significantly to delayed healing. Bacteria in biofilms are highly tolerant of antimicrob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8946be8d90cad416b9b6600919c01276
https://pubmed.ncbi.nlm.nih.gov/27859922
https://pubmed.ncbi.nlm.nih.gov/27859922