Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Daniel J. Farrugia"'
Autor:
Brian J. Gebhardt, MD, Joel Thomas, BA, Zachary D. Horne, MD, Colin E. Champ, MD, Daniel J. Farrugia, MD, PhD, Emilia Diego, MD, Gretchen M. Ahrendt, MD, Sushil Beriwal, MD
Publikováno v:
Advances in Radiation Oncology, Vol 3, Iss 3, Pp 258-264 (2018)
Purpose: The American College of Surgeons Oncology Group trial Z0011 demonstrated that axillary node dissection (ALND) can be omitted in patients managed with breast conserving surgery and 1 to 2 positive sentinel lymph nodes (SLNs) without adverse e
Externí odkaz:
https://doaj.org/article/de68aad0029447c6beea79839863c1a2
Autor:
Gretchen M. Ahrendt, Joel Thomas, Colin E. Champ, Daniel J. Farrugia, Emilia J Diego, Brian J. Gebhardt, Sushil Beriwal, Zachary D. Horne
Publikováno v:
Advances in Radiation Oncology, Vol 3, Iss 3, Pp 258-264 (2018)
Advances in Radiation Oncology
Advances in Radiation Oncology
Purpose The American College of Surgeons Oncology Group trial Z0011 demonstrated that axillary node dissection (ALND) can be omitted in patients managed with breast conserving surgery and 1 to 2 positive sentinel lymph nodes (SLNs) without adverse ef
Autor:
Li Zhu, Gretchen M. Ahrendt, Rachel C. Jankowitz, Emilia J Diego, Atilla Soran, Priscilla F. McAuliffe, Alessandra Landmann, Adam Brufsky, Ronald Johnson, David J. Dabbs, Beth Z. Clark, Rohit Bhargava, Daniel J. Farrugia, Shannon Puhalla
Publikováno v:
American Journal of Clinical Pathology. 150:34-42
Objectives Pathologic complete response (pCR) rate after neoadjuvant chemotherapy was compared between 141 estrogen receptor (ER)-negative (43%), 41 low ER+ (13%), 47 moderate ER+ (14%), and 98 high ER+ (30%) tumors. Methods Human epidermal growth fa
Autor:
Shannon Puhalla, Rohit Bhargava, Emilia J Diego, David J. Dabbs, Alessandra Landmann, Adam Brufsky, Beth Z. Clark, Rachel C. Jankowitz, Priscilla F. McAuliffe, Daniel J. Farrugia, Gretchen M. Ahrendt
Publikováno v:
American Journal of Clinical Pathology. 149:332-343
Objectives We hypothesized that prognostic accuracy of the residual disease in breast and lymph nodes (RDBN) method, which is calculated using residual tumor size, nodal involvement, and tumor grade, may be improved by incorporating residual tumor ce
Autor:
Marguerite Bonaventura, Shannon Puhalla, Atilla Soran, Priscilla F. McAuliffe, Rohit Bhargava, Barry C. Lembersky, Daniel J. Farrugia, Alessandra Landmann, Ronald Johnson, Rachel C. Jankowitz, Beth Z. Clark, Adam Brufsky, G Ahrendt, David J. Dabbs, Nancy E. Davidson, Emilia J Diego
Publikováno v:
Cancer Research. 77:P6-09
Background: Patients achieving pathologic complete response to neoadjuvant chemotherapy have excellent disease free and overall survival. For patients with residual disease, the residual disease in breast and lymph node (RDBN) method provides useful
Autor:
Alessandra, Landmann, Daniel J, Farrugia, Li, Zhu, Emilia J, Diego, Ronald R, Johnson, Atilla, Soran, David J, Dabbs, Beth Z, Clark, Shannon L, Puhalla, Rachel C, Jankowitz, Adam M, Brufsky, Gretchen M, Ahrendt, Priscilla F, McAuliffe, Rohit, Bhargava
Publikováno v:
American journal of clinical pathology. 150(1)
Pathologic complete response (pCR) rate after neoadjuvant chemotherapy was compared between 141 estrogen receptor (ER)-negative (43%), 41 low ER+ (13%), 47 moderate ER+ (14%), and 98 high ER+ (30%) tumors.Human epidermal growth factor receptor 2-posi
Autor:
Rohit Bhargava, Li Zhu, Beth Z. Clark, Ronald Johnson, Daniel J. Farrugia, Alessandra Landmann, Gretchen M. Ahrendt, Adam Brufsky, David J. Dabbs, Marguerite Bonaventura, Emilia J Diego, Rachel C. Jankowitz, Atilla Soran, Priscilla F. McAuliffe, Shannon Puhalla, Barry C. Lembersky
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 30(8)
Magee Equations were derived as an inexpensive, rapid alternative to Oncotype DX. The Magee Equation 3 utilizes immunohistochemical and FISH data for estrogen receptor (ER), progesterone receptor (PR), HER2 and Ki-67 for its calculation (24.30812+ERI
Autor:
Sunil R. Lakhani, Melissa A. Brown, Samantha Butler, Feng Lin, Diana Eccles, Amanda B. Spurdle, Bryony A. Thompson, David E. Goldgar, Sue Healey, Phillip J. Whiley, Leonard Da Silva, Logan C. Walker, Sheila A. Goff, Fergus J. Couch, Daniel J. Farrugia, Sean V. Tavtigian
Publikováno v:
Human Mutation. 31:E1484-E1505
Missense substitutions in high-risk cancer susceptibility genes create clinical uncertainty in the genetic counseling process. Multifactorial likelihood classification approaches and in vitro assays are useful for the classification of exonic sequenc
Autor:
I. D. Acu, Franca Stivala, Evanthia Galanis, Mark A. Schroeder, A B D'Assoro, M. M. Reinholz, Daniel J. Farrugia, Cosima Quatraro, Jeffrey L. Salisbury, Robert Busby, Cory Allen
Publikováno v:
Oncogene. 27:3901-3911
In this study, we establish an MCF-7 xenograft model that mimics the progression of human breast carcinomas typified by loss of p53 integrity, development of centrosome amplification, acquired estrogen receptor (ERalpha) heterogeneity, overexpression
Autor:
Daniel J. Farrugia, Nicole Urban, Wataru Sakai, Fergus J. Couch, Céline Jacquemont, Mukesh K. Agarwal, Toshiyasu Taniguchi, Emily Villegas, Jake Higgins, Beth Y. Karlan, Cynthia Friedman, Elizabeth M. Swisher
Publikováno v:
Nature. 451:1116-1120
Ovarian carcinomas with mutations in the tumour suppressor BRCA2 are particularly sensitive to platinum compounds. However, such carcinomas ultimately develop cisplatin resistance. The mechanism of that resistance is largely unknown. Here we show tha