Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Daniel J. Farkas"'
Publikováno v:
IBRO Neuroscience Reports, Vol 13, Iss , Pp 198-206 (2022)
Mitragynine (MG) is an alkaloid found in Mitragyna speciosa (kratom) that is used as an herbal remedy for pain relief and opioid withdrawal. MG acts at μ-opioid and α-adrenergic receptors in vitro, but the physiological relevance of this activity i
Externí odkaz:
https://doaj.org/article/9436e54f95234d179a52313b4d7c54ea
Autor:
Angela R. Bongiovanni, Pingwei Zhao, Saadet Inan, Sonita Wiah, Aryan Shekarabi, Daniel J. Farkas, Mia N. Watson, Mathieu E. Wimmer, Michael R. Ruff, Scott M. Rawls
Publikováno v:
Drug Alcohol Depend
Chemokine-opioid crosstalk is a physiological crossroads for influencing therapeutic and adverse effects of opioids. Activation of chemokine receptors, especially CCR2, CCR5 and CXCR4, reduces opioid-induced analgesia by desensitizing OPRM1 receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d62dd43e882cd05f1938ef899adaf7b0
https://europepmc.org/articles/PMC9444981/
https://europepmc.org/articles/PMC9444981/
Autor:
Raghava Potula, Taylor A. Gentile, Joseph J. Meissler, Aryan Shekarabi, Sonita Wiah, Daniel J. Farkas, Saadet Inan, Toby K. Eisenstein, Scott M. Rawls
Publikováno v:
Brain, behavior, and immunity. 107
P2X7 receptors are dysregulated during psychostimulant exposure. Furthermore, P2X7 receptors enhance endogenous systems (e.g., cytokines, dopamine, and glutamate) that facilitate psychostimulant addiction. Therefore, using mouse locomotor, conditione
Publikováno v:
The FASEB Journal. 36
Autor:
Sonita, Wiah, Abigail, Roper, Pingwei, Zhao, Aryan, Shekarabi, Mia N, Watson, Daniel J, Farkas, Raghava, Potula, Allen B, Reitz, Scott M, Rawls
Publikováno v:
Drug and Alcohol Dependence. 242:109719
Riluzole, approved to manage amyotrophic lateral sclerosis, is mechanistically unique among glutamate-based therapeutics because it reduces glutamate transmission through a dual mechanism (i.e., reduces glutamate release and enhances glutamate reupta
Publikováno v:
SSRN Electronic Journal.
Mitragynine (MG) is an alkaloid found in
Autor:
Daniel J. Farkas, Lana M. Huynh, Douglas E. Brenneman, William A. Kinney, Sara Jane Ward, Jeffery D. Foss
Publikováno v:
British journal of pharmacologyREFERENCES. 178(15)
Background and purpose Cannabidiol (CBD) is a non-euphorigenic component of Cannabis sativa which prevents the development of paclitaxel-induced mechanical sensitivity in a mouse model of chemotherapy-induced peripheral neuropathy (CIPN). We recently
Autor:
Sunil U. Nayak, Jeffery D. Foss, Sara Jane Ward, Daniel J. Farkas, Christopher S. Tallarida, Scott M. Rawls
Publikováno v:
Drug Alcohol Depend
Background and Purpose Kratom is a coffee-like plant containing compounds that cause opioid and stimulant effects. The most prevalent bioactive alkaloid of kratom is mitragynine (MG). Opioid effects of MG are apparent (e.g. antinociception and nanomo
Autor:
Reshu Saxena, Caitlin Tice, Kishan Patel, Erika G. Karassik, Kelly A. Whelan, Henry P. Parkman, Julie Gang, Mary Grace Murray, Alena Klochkova, Timothy M. Hall, Marie Pier Tetreault, Sarah J. Ward, Daniel J. Farkas, Zachary Wilmer Reichenbach
Esophageal squamous cell carcinoma (ESCC) is among the most deadly forms of human malignancy characterized by late stage diagnosis, metastasis, therapy resistance and frequent recurrence. Clinical management of ESCC remains challenging and the diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72e2cf21d5a32911b014fe0923c63ffe
https://doi.org/10.1016/bs.acr.2019.05.004
https://doi.org/10.1016/bs.acr.2019.05.004