Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Daniel J. Bogan"'
Autor:
Martin K Childers, Janet R Bogan, Daniel J Bogan, Hansel eGreiner, Melanie eHolder, Robert eGrange, Joe N Kornegay
Publikováno v:
Frontiers in Pharmacology, Vol 2 (2012)
Calpains likely play a role in the pathogenesis of Duchenne muscular dystrophy (DMD). Accordingly, calpain inhibition may provide therapeutic benefit to DMD patients. In the present study, we sought to measure benefit from administration of a novel c
Externí odkaz:
https://doaj.org/article/1a7baa2e340b44a8b4b8f6a6c8846663
Autor:
Cynthia J. Balog-Alvarez, Mihye Ahn, Robert W. Grange, Kathryn R. Wagner, Candice Brinkmeyer-Langford, Carl Morris, Daniel J. Bogan, Martin Styner, Hongtu Zhu, Joe N. Kornegay, Leigh C. Warsing, Steven W. Cotten, Naili Liu, Jiahui Wang, Jennifer L. Dow, Janet R. Bogan, Joe Palandra, Monte S. Willis, Zheng Fan
Publikováno v:
Skeletal Muscle
Background Myostatin (Mstn) is a negative regulator of muscle growth whose inhibition promotes muscle growth and regeneration. Dystrophin-deficient mdx mice in which myostatin is knocked out or inhibited postnatally have a less severe phenotype with
Autor:
Jiahui Wang, Kathryn R. Wagner, Joe N. Kornegay, Scott J. Schatzberg, Zheng Fan, Peter P. Nghiem, Martin K. Childers, Martin Styner, Daniel J. Bogan, James F. Howard, Janet R. Bogan, Robert W. Grange, Eric P. Hoffman, Jennifer L. Dow
Publikováno v:
Physical Medicine and Rehabilitation Clinics of North America. 23:149-172
Mutations in the dystrophin gene cause Duchenne and Becker muscular dystrophy in humans and syndromes in mice, dogs, and cats. Affected humans and dogs have progressive disease that leads primarily to muscle atrophy. Mdx mice progress through an init
Publikováno v:
Neuromuscular Disorders. 13:493-500
The degree of atrophy or hypertrophy of selected pelvic limb muscles was determined in the canine homologue of Duchenne muscular dystrophy. While most muscles were atrophied, the caudal and cranial sartorius were hypertrophied. Cranial sartorius weig
Autor:
Joe N. Kornegay, Margaret J. Sullivan, Martin K. Childers, Carol S. Okamura, Daniel J. Bogan, Janet R. Bogan
Publikováno v:
American Journal of Physical Medicine & Rehabilitation. 80:175-181
Objective To test the hypothesis that differential skeletal muscle involvement, previously observed in dogs with a homologue of Duchenne muscular dystrophy, correlates with the histochemical markers of myofiber injury and regeneration. Design Evidenc
Autor:
Chad D. Markert, Robert W. Grange, Christopher J. Tegeler, Doug Case, Martin K. Childers, Daniel J. Bogan, Joe N. Kornegay
Publikováno v:
Muscle & Nerve. 42:130-132
We tested the hypothesis that eccentric contractions (ECCs) rapidly induce greater-than-normal isometric torque drop in dystrophin-deficient golden retriever muscular dystrophy (GRMD) muscles. ECCs were imposed by forcibly stretching activated muscle
Autor:
Janet R. Bogan, Justin C. DeVanna, Joe N. Kornegay, Eleanor C. Hawkins, Daniel J. Bogan, Jennifer L. Dow
Publikováno v:
Neuromuscular disorders : NMD. 24(1)
Golden retriever muscular dystrophy (GRMD) is a well-established model of Duchenne muscular dystrophy. The value of this model would be greatly enhanced with practical tools to monitor progression of respiratory dysfunction during treatment trials. A
Autor:
Peter P. Nghiem, David A. Detwiler, Zheng Fan, Jiahui Wang, Kevin M. Flanigan, Daniel J. Bogan, Eric P. Hoffman, Scott J. Schatzberg, Sandra P. Tou, Robert W. Grange, Ratna Bhavaraju-Sanka, Martin K. Childers, Joe N. Kornegay, Xiao Xiao, Bruce P. Keene, James F. Howard, Juan Li, C. Aaron Larsen, Janet R. Bogan, Martin Styner
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder in which the loss of dystrophin causes progressive degeneration of skeletal and cardiac muscle. Potential therapies that carry substantial risk, such as gene and cell-based approache
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08786c7ab7577718d12cf4e983ab8abd
https://europepmc.org/articles/PMC3911884/
https://europepmc.org/articles/PMC3911884/
Autor:
Hansel M. Greiner, Janet R. Bogan, Martin K. Childers, Robert W. Grange, Joe N. Kornegay, Melanie Holder, Daniel J. Bogan
Publikováno v:
Frontiers in Pharmacology, Vol 2 (2012)
Frontiers in Pharmacology
Frontiers in Pharmacology
Calpains likely play a role in the pathogenesis of Duchenne muscular dystrophy (DMD). Accordingly, calpain inhibition may provide therapeutic benefit to DMD patients. In the present study, we sought to measure benefit from administration of a novel c
Autor:
Ronald O. Schueler, Steven D. Van Camp, Daniel J. Bogan, Janet R. Metcalf, Joe N. Kornegay, Nicholas J.H. Sharp
Publikováno v:
Journal of the Neurological Sciences. 123:100-107
Contraction tension and kinetics of the peroneus longus muscle were studied in dogs with the Duchenne homologue, golden retriever muscular dystrophy (GRMD), in advance of evaluating localized therapies such as myoblast transplantation. Absolute and b