Výsledky vyhledávání - "Daniel J. Bayston"

Simple and efficient preparation of dihydropyrans and spiroketals using the intramolecular silyl modified Sakurai (ISMS) reaction

Autor: István E. Markó, A. Mekhalfia, Harry Adams, Daniel J. Bayston

Publikováno v: Bulletin des Sociétés Chimiques Belges. 102:655-661

Substituted tetrahydropyrans, spiroethers and spiroketals can be prepared in a single step using the ISMS reaction between the bis-silylated reagent 7b and aldehydes (acetals), ketones (ketals) and ortholactones respectively. This simple methodology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3be10fe894c3231850af4cc4bebd945a
https://doi.org/10.1002/bscb.19931021006

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Tandem Ene-Reaction/Intramolecular Sakurai Cyclisation (IMSC): A Novel Access to Polysubstituted Tetrahydropyrans and γ-Butyrolactones Using a Unique Allylation Strategy

Autor: Daniel J. Bayston, Raphael Dumeunier, István E. Markó, Jean-Marc Plancher, Cedric Leclercq, Abdelaziz Mekhalfia, Bernard Leroy

Publikováno v: Synthesis. 2002:958-972

The ene-reaction between a variety of aldehydes and allylsilane 22 generates highly functionalised homoallylic alcohols 23. These adducts undergo a subsequent Intramolecular Sakurai Cyclisation (IMSC), affording in good yields polysubstituted tetrahy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b1d91149dce521ec6188de727db10f2
https://doi.org/10.1055/s-2002-28506

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Concise and stereocontrolled assembly of substituted dihydropyrans. Synthetic studies towards the trans-dioxadecalin subunit of okadaic acid

Autor: Daniel J. Bayston, Adrian P. Dobbs, István E. Markó, François Chellé, Vincent Scheirmann

Publikováno v: Tetrahedron Letters. 38:2899-2902

A simple methodology for the stereocontrolled synthesis of dihydropyrans has been established. The trans-dioxadecalin 22, featuring the middle portion of okadaic acid, has been efficiently assembled using this strategy. (C) 1997 Elsevier Science Ltd.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d928f8c3bc6fd48b8ae5b0b0ca181495
https://doi.org/10.1016/s0040-4039(97)00471-1

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Towards the Total Synthesis of Ambruticin: Preparation of the Fully Functionalised Right-Hand Portion Using the Intramolecular Silyl-Modified Sakurai (ISMS) Annulation

Autor: István E. Markó, Daniel J. Bayston

Publikováno v: Synthesis. 1996:297-304

The concise synthesis of the fully functionalised right-hand dihydropyran subunit of the antifungal antibiotic ambruticin (1), using the ISMS annulation as the key-step, is described.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0c37a0f6abed083231fa0864588aa7ff
https://doi.org/10.1055/s-1996-4185

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The Intramolecular Silyl-Modified Sakurai (ISMS) reaction. Synthetic studies towards ambruticine

Autor: István E. Markó, Daniel J. Bayston

Publikováno v: Tetrahedron. 50:7141-7156

The ISMS reaction has been used to efficiently construct the right-hand portion 3 of the antifungal antibiotic ambruticine 1.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::611a560333989e20d721b5f7fba63f0d
https://doi.org/10.1016/s0040-4020(01)85240-6

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The Intramolecular Silyl-Modified Sakurai (ISMS) reaction. Stereoselective preparation of tri-and tetra-substituted tetrahydropyrans

Autor: Daniel J. Bayston, István E. Markó

Publikováno v: Tetrahedron Letters. 34:6595-6598

The ISMS condensation of allylsilane 4 does not follow the expected pathway but rather leads to an efficient synthesis of trisubstituted and tetrasubstituted tetrahydropyran derivatives.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4747f87ebc851775a675540405464ab
https://doi.org/10.1016/0040-4039(93)88114-x

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ChemInform Abstract: The Intramolecular Silyl-Modified Sakurai (ISMS) Reaction. Stereoselective Preparation of Tri- and Tetra-Substituted Tetrahydropyrans

Autor: Daniel J. Bayston, István E. Markó

Publikováno v: ChemInform. 25

The ISMS condensation of allylsilane 4 does not follow the expected pathway but rather leads to an efficient synthesis of trisubstituted and tetrasubstituted tetrahydropyran derivatives.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::758867f4eaf9cdba9b367324e273a839
https://doi.org/10.1002/chin.199417160

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