Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Daniel J. Mastarone"'
Autor:
Emily A. Waters, Daniel J. Mastarone, Thomas J. Meade, Nikhil Rammohan, Laura M. Lilley, Adam T. Preslar, Giacomo Parigi, Laura K. Moore, Claudio Luchinat, Lisa M. Manus, Keith W. MacRenaris, Abigail Filicko, Dean Ho
Publikováno v:
Nano Letters. 16:7551-7564
The ability to track labeled cancer cells in vivo would allow researchers to study their distribution, growth, and metastatic potential within the intact organism. Magnetic resonance (MR) imaging is invaluable for tracking cancer cells in vivo as it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793d470da5fc2bcd896acd6699621385
https://doi.org/10.1021/acs.nanolett.6b03378
https://doi.org/10.1021/acs.nanolett.6b03378
Autor:
David R. Kasjanski, Daniel J. Mastarone, Andy H. Hung, Keith W. MacRenaris, Christiane E. Carney, Thomas J. Meade
Publikováno v:
Bioconjugate Chemistry
Cell tracking in vivo with MR imaging requires the development of contrast agents with increased sensitivity that effectively label and are retained by cells. Most clinically approved Gd(III)-based contrast agents require high incubation concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::755dd2bc8dff4443050dfcb17ff21d87
https://doi.org/10.1021/bc500083t
https://doi.org/10.1021/bc500083t
Autor:
Patrick L. Hankins, Richard W. Ahn, Anthony J. Chipre, Daniel J. Mastarone, Elden P. Swindell, Thomas V. O'Halloran, Thomas J. Meade, Bong Jin Hong, Keith W. MacRenaris, SonBinh T. Nguyen
Publikováno v:
Particle & Particle Systems Characterization. 30:770-774
Recent advances in nanotechnology, materials science, and biotechnology have enabled the design of theranostic nanoparticles that co-deliver therapeutic compounds and imaging probes in a single platform to heterogeneous disease sites such as tumors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48047ff08ae8e4440d3a973f0c95a6dd
https://doi.org/10.1002/ppsc.201300158
https://doi.org/10.1002/ppsc.201300158
Autor:
Thomas J. Meade, Jonathan J. Ipsaro, Renee C. Strauch, Daniel J. Mastarone, Ying Song, Preeti A. Sukerkar
Publikováno v:
Journal of the American Chemical Society. 133:16346-16349
Contrast agents for magnetic resonance imaging are frequently employed as experimental and clinical probes. Drawbacks include low signal sensitivity, fast clearance, and nonspecificity that limit efficacy in experimental imaging. In order to create a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d81d5157e1ac97ee24ea93cc9097a7
https://doi.org/10.1021/ja206134b
https://doi.org/10.1021/ja206134b
Autor:
Thomas J. Meade, Bong Jin Hong, SonBinh T. Nguyen, Daniel J. Mastarone, Keith W. MacRenaris, Ying Song, Sang Min Lee, Thomas V. O'Halloran
Publikováno v:
Angewandte Chemie. 122:10156-10160
Magnetic resonance imaging (MRI) can provide detailedhigh-resolution, tomographic information of disease tissue inreal time and in vivo. Hence, it has become a powerfuldiagnostic tool for detecting the stages of primary andrecurrent solid tumors and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56744b4d308069ae4875ebd044e17bda
https://doi.org/10.1002/ange.201004867
https://doi.org/10.1002/ange.201004867
Autor:
Bong Jin, Hong, Elden P, Swindell, Keith W, Macrenaris, Patrick L, Hankins, Anthony J, Chipre, Daniel J, Mastarone, Richard W, Ahn, Thomas J, Meade, Thomas V, O'Halloran, Sonbinh T, Nguyen
Publikováno v:
Particleparticle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems. 30(9)
A PCN theranostic platform comprises a doxorubicin (DXR)-loaded liposomal core and an acid-sensitive polymer shell that is functionalized with Herceptin and GdIII-based MRI contrast agents. In vitro testing reveals a 14-fold increase in DXR-based cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ca79b2619f3bfed1615b36f621feff7
https://pubmed.ncbi.nlm.nih.gov/24516291
https://pubmed.ncbi.nlm.nih.gov/24516291
Autor:
Matthew W. Rotz, Andy H. Hung, Thomas J. Meade, Daniel J. Mastarone, Keith W. MacRenaris, Matthew C. Duch, Colton C. Gits, Mark C. Hersam, Giacomo Parigi, Kevin T. Dam, Lisa M. Manus, Claudio Luchinat
Publikováno v:
The journal of physical chemistry. C, Nanomaterials and interfaces. 117(31)
Gd(III) associated with carbon nanomaterials relaxes water proton spins at an effectiveness that approaches or exceeds the theoretical limit for a single bound water molecule. These Gd(III)-labeled materials represent a potential breakthrough in sens
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3b08cca55c5206f698da194eb9f494
https://pubmed.ncbi.nlm.nih.gov/24298299
https://pubmed.ncbi.nlm.nih.gov/24298299
Autor:
Daniel J. Mastarone, S. Shaun Murphree, Ryan K. Murphy, Amy C. Bonaparte, Bettina M. Panseri, Matthew P. Betush
Publikováno v:
ChemInform. 42
With commercially available 13C-labeled methyl phenyl sulfone, the preparation of useful labeled carboxylic acids is possible.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e6188266a38c7163e07b52fb9bdab6
https://doi.org/10.1002/chin.201124054
https://doi.org/10.1002/chin.201124054
Autor:
Amanda L. Eckermann, Victoria S. R. Harrison, Claudio Luchinat, Thomas J. Meade, Daniel J. Mastarone, Giacomo Parigi
We have developed a modular architecture for preparing high-relaxivity multiplexed probes utilizing click chemistry. Our system incorporates azide bearing Gd(III) chelates and a trialkyne scaffold with a functional group for subsequent modification.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb69b9d40100ec8b1c476442515bf2f0
https://europepmc.org/articles/PMC3086647/
https://europepmc.org/articles/PMC3086647/
Autor:
Ryan K. Murphy, S. Shaun Murphree, Daniel J. Mastarone, Bettina M. Panseri, Matthew P. Betush, Amy C. Bonaparte
Publikováno v:
Organic letters. 13(6)
Primary alkyl aryl sulfones are converted to the corresponding carboxylic acids in fair to excellent yield through double deprotonation and exposure to atmospheric oxygen. The methodology allows for the convenient synthesis of (13)C labeled carboxyli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e77ba89e0b14919c38dd7d3b60c8419
https://pubmed.ncbi.nlm.nih.gov/21319833
https://pubmed.ncbi.nlm.nih.gov/21319833