Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daniel J Wright"'
Autor:
Sara M. Willems, Daniel J. Wright, Felix R. Day, Katerina Trajanoska, Peter K. Joshi, John A. Morris, Amy M. Matteini, Fleur C. Garton, Niels Grarup, Nikolay Oskolkov, Anbupalam Thalamuthu, Massimo Mangino, Jun Liu, Ayse Demirkan, Monkol Lek, Liwen Xu, Guan Wang, Christopher Oldmeadow, Kyle J. Gaulton, Luca A. Lotta, Eri Miyamoto-Mikami, Manuel A. Rivas, Tom White, Po-Ru Loh, Mette Aadahl, Najaf Amin, John R. Attia, Krista Austin, Beben Benyamin, Søren Brage, Yu-Ching Cheng, Paweł Cięszczyk, Wim Derave, Karl-Fredrik Eriksson, Nir Eynon, Allan Linneberg, Alejandro Lucia, Myosotis Massidda, Braxton D. Mitchell, Motohiko Miyachi, Haruka Murakami, Sandosh Padmanabhan, Ashutosh Pandey, Ioannis Papadimitriou, Deepak K. Rajpal, Craig Sale, Theresia M. Schnurr, Francesco Sessa, Nick Shrine, Martin D. Tobin, Ian Varley, Louise V. Wain, Naomi R. Wray, Cecilia M. Lindgren, Daniel G. MacArthur, Dawn M. Waterworth, Mark I. McCarthy, Oluf Pedersen, Kay-Tee Khaw, Douglas P. Kiel, GEFOS Any-Type of Fracture Consortium, Yannis Pitsiladis, Noriyuki Fuku, Paul W. Franks, Kathryn N. North, Cornelia M. van Duijn, Karen A. Mather, Torben Hansen, Ola Hansson, Tim Spector, Joanne M. Murabito, J. Brent Richards, Fernando Rivadeneira, Claudia Langenberg, John R. B. Perry, Nick J. Wareham, Robert A. Scott
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Hand grip strength as a proxy of muscular fitness is a clinical predictor of mortality and morbidity. In a large-scale GWA study, the authors find 16 robustly associated genetic loci that highlight roles in muscle fibre structure and function, neuron
Externí odkaz:
https://doaj.org/article/c79d45da5079409b8be2da8ab36a65af
Autor:
Ragnar P. Kristjansson, Steven A. McCarroll, Florian Zink, Malcolm G. Dunlop, Nicholas J. Wareham, Yoichiro Kamatani, Daniel F. Gudbjartsson, Giulio Genovese, Rong Li, Stephen J. Chanock, Unnur Thorsteinsdottir, Ben Kinnersley, Kari Stefansson, Philip J. Law, Martin Ingelsson, Lars Forsberg, Joe Dennis, Richard S. Houlston, Jonatan Halvardson, Nicola D. Kerrison, Chikashi Terao, Douglas F. Easton, Anna Murray, Yunxuan Jiang, Jan P. Dumanski, Chey Loveday, Steve P Jackson, Robert A. Scott, Edyta Rychlicka-Buniowska, Ian Tomlinson, Daniel J Wright, Deborah J. Thompson, Victoria A Fisher, Yoshinori Murakami, John R. B. Perry, Paweł Olszewski, Felix R. Day, Eva Hoffmann, Hanna Davies, Po-Ru Loh, Adam Auton, Siddhartha Kar, Behrooz Torabi Moghadam, Clare Turnbull, Ken K. Ong, Marcus Danielsson, Jacob C. Ulirsch, Jonas Mattisson, Patrick Sulem, Olafur B. Davidsson, Mitchell J. Machiela
Publikováno v:
Thompson, D J, Genovese, G, Kar, S, Perry, J RB & et al. 2019, ' Genetic predisposition to mosaic Y chromosome loss in blood ', Nature, vol. 575, pp. 652–657 . https://doi.org/10.1038/s41586-019-1765-3
Nature, 575(7784), 652-657. Nature Publishing Group
Thompson, D J, Genovese, G, Forsberg, L A, Perry, J R B, International Lung Cancer Consortium (INTEGRAL-ILCCO), Boomsma, D, Nivard, M, van Dongen, J, Pool, R & Hottenga, J J 2019, ' Genetic predisposition to mosaic Y chromosome loss in blood ', Nature, vol. 575, no. 7784, pp. 652-657 . https://doi.org/10.1038/s41586-019-1765-3
Nature
2019, ' Genetic predisposition to mosaic Y chromosome loss in blood ', Nature, vol. 575, no. 7784, pp. 652-657 . https://doi.org/10.1038/s41586-019-1765-3
Thompson, D J, Genovese, G, Halvardson, J, Ulirsch, J C, Wright, D J, Terao, C, Davidsson, O B, Day, F R, Sulem, P, Jiang, Y, Danielsson, M, Davies, H, Dennis, J, Dunlop, M G, Easton, D F, Fisher, V A, Zink, F, Houlston, R S, Ingelsson, M, Kar, S, Kerrison, N D, Kinnersley, B, Kristjansson, R P, Law, P J, Li, R, Loveday, C, Mattisson, J, McCarroll, S A, Murakami, Y, Murray, A, Olszewski, P, Rychlicka-Buniowska, E, Scott, R A, Thorsteinsdottir, U, Tomlinson, I, Moghadam, B T, Turnbull, C, Wareham, N J, Gudbjartsson, D F, Kamatani, Y, Hoffmann, E R, Jackson, S P, Stefansson, K, Auton, A, Ong, K K, Machiela, M J, Loh, P-R, Dumanski, J P, Chanock, S J, Forsberg, L A, International Lung Cancer Consortium (INTEGRAL-ILCCO) & The PRACTICAL Consortium 2019, ' Genetic predisposition to mosaic Y chromosome loss in blood ', Nature, vol. 575, no. 7784, pp. 652-657 . https://doi.org/10.1038/s41586-019-1765-3
Nature, 575(7784), 652-657. Nature Publishing Group
Thompson, D J, Genovese, G, Forsberg, L A, Perry, J R B, International Lung Cancer Consortium (INTEGRAL-ILCCO), Boomsma, D, Nivard, M, van Dongen, J, Pool, R & Hottenga, J J 2019, ' Genetic predisposition to mosaic Y chromosome loss in blood ', Nature, vol. 575, no. 7784, pp. 652-657 . https://doi.org/10.1038/s41586-019-1765-3
Nature
2019, ' Genetic predisposition to mosaic Y chromosome loss in blood ', Nature, vol. 575, no. 7784, pp. 652-657 . https://doi.org/10.1038/s41586-019-1765-3
Thompson, D J, Genovese, G, Halvardson, J, Ulirsch, J C, Wright, D J, Terao, C, Davidsson, O B, Day, F R, Sulem, P, Jiang, Y, Danielsson, M, Davies, H, Dennis, J, Dunlop, M G, Easton, D F, Fisher, V A, Zink, F, Houlston, R S, Ingelsson, M, Kar, S, Kerrison, N D, Kinnersley, B, Kristjansson, R P, Law, P J, Li, R, Loveday, C, Mattisson, J, McCarroll, S A, Murakami, Y, Murray, A, Olszewski, P, Rychlicka-Buniowska, E, Scott, R A, Thorsteinsdottir, U, Tomlinson, I, Moghadam, B T, Turnbull, C, Wareham, N J, Gudbjartsson, D F, Kamatani, Y, Hoffmann, E R, Jackson, S P, Stefansson, K, Auton, A, Ong, K K, Machiela, M J, Loh, P-R, Dumanski, J P, Chanock, S J, Forsberg, L A, International Lung Cancer Consortium (INTEGRAL-ILCCO) & The PRACTICAL Consortium 2019, ' Genetic predisposition to mosaic Y chromosome loss in blood ', Nature, vol. 575, no. 7784, pp. 652-657 . https://doi.org/10.1038/s41586-019-1765-3
Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common form of clonal mosaicism1–5, yet our knowledge of the causes and consequences of this is limited. Here, using a computational approach, we estimate that 20% of th
Autor:
Jordan R. Barrett, Teresa Lambe, Carina Conceicao, Oliver T. Burton, Sigrid Fra-Bido, Adrian Liston, Alyssa Silva-Cayetano, Alexandra J. Spencer, Sandra Belij-Rammerstorfer, William S. Foster, Michelle A. Linterman, Silvia Innocentin, Nazia Thakur, Carly Noble, Sarah C. Gilbert, Jia Le Lee, Nicola Evans-Bailey, Daniel J Wright, Dalan Bailey
Publikováno v:
Med (New York, N.y.)
Med
Med
Background The spread of SARS-CoV-2 has caused a worldwide pandemic that has affected almost every aspect of human life. The development of an effective COVID-19 vaccine could limit the morbidity and mortality caused by infection and may enable the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509616b43c289690b9ca228b928b12da
https://www.repository.cam.ac.uk/handle/1810/317920
https://www.repository.cam.ac.uk/handle/1810/317920
Publikováno v:
Nucleic Acids Research
Inosine is found naturally in the anticodon loop of tRNA, is a product of adenosine deaminases that act on RNA, and can be used in oligonucleotide probes or to investigate the role of the exocyclic amino group of guanosine. Although the thermodynamic
Autor:
Laura G. Rosen, Justine Renard, Hanna J. Szkudlarek, Daniel J. Wright, Christina L M Jobson, Steven R. Laviolette, Walter J. Rushlow, Brian J. Pereira
Publikováno v:
Cerebral Cortex. 29:3140-3153
Considerable evidence demonstrates strong comorbidity between nicotine dependence and mood and anxiety disorders. Nevertheless, the neurobiological mechanisms linking adolescent nicotine exposure to mood and anxiety disorders are not known. Disturban
Autor:
Steven R. Laviolette, Walter J. Rushlow, Roger Hudson, Christina E. L. Jobson, Daniel J. Wright, Tony Jung, Justine Renard, Matthew R. Green
Publikováno v:
Addiction biologyREFERENCES. 26(2)
Long-term tobacco dependence typically develops during adolescence and neurodevelopmental nicotine exposure is associated with affective disturbances that manifest as a variety of neuropsychiatric comorbidities in clinical and preclinical studies, in
Autor:
Walter J. Rushlow, Hanna J. Szkudlarek, Daniel J. Wright, Steven R. Laviolette, Justine Renard
Publikováno v:
The FASEB Journal. 32
Autor:
Svanhvit Sigurjonsdottir, Kari Stefansson, Unnur Thorsteindottir, Alexia Cardona, Daniel F. Gudbjartsson, Nicholas J. Wareham, J. Ross Chapman, Nicola D. Kerrison, John R. B. Perry, Felix R. Day, Steve P Jackson, Deborah J. Thompson, Daniel J Wright, Agnar Helgason, Patrick Sulem, Florian Zink, Ken K. Ong, Robert A. Scott, Claudia Langenberg
Publikováno v:
Nature genetics
The Y chromosome is frequently lost in hematopoietic cells, which represents the most common somatic alteration in men. However, the mechanisms that regulate mosaic loss of chromosome Y (mLOY), and its clinical relevance, are unknown. We used genotyp
Publikováno v:
European Journal of Cell Biology. 85:1201-1215
In budding yeast the final stages of the cell division cycle, cytokinesis and cell separation, are distinct events that require to be coupled, both together and with mitotic exit. Here we demonstrate that mutations in genes of the mitotic exit networ
The nicotinic acetylcholine receptor (AChR) current of outer hair cells (OHCs) was investigated in isolated and voltage-clamped cells under conditions where co-activating Ca(2+)-activated K(+) currents had been abolished using internal BAPTA, externa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894363c0a5eb5228d4570f438f7dd19f
https://europepmc.org/articles/PMC3015032/
https://europepmc.org/articles/PMC3015032/