Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Daniel J Toth"'
Autor:
Tamas Balla, Joshua G. Pemberton, Nivedita Sengupta, Jana Humpolíčková, Daniel J Toth, Yeun Ju Kim, Evzen Boura, Andrea Eisenreichova
Publikováno v:
The Journal of Cell Biology
Pemberton et al. characterize a molecular toolbox for the visualization and manipulation of phosphatidylinositol (PI) within intact cells. Results using these approaches define the steady-state distribution of PI across subcellular membrane compartme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0f9369590b52338cea84ef25be0a1d8
http://europepmc.org/articles/PMC7054996
http://europepmc.org/articles/PMC7054996
Autor:
Daniel J Toth, Nivedita Sengupta, Joshua G. Pemberton, Yeun Ju Kim, Andrea Eisenreichova, Tamas Balla, Evzen Boura
Phosphatidylinositol (PtdIns) is an essential structural component of eukaryotic membranes that also serves as the common precursor for polyphosphoinositide (PPIn) lipids. Despite the recognized importance of PPIn species for signal transduction and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b9a0b4f8624286ccb84baec6f9e4f4
https://doi.org/10.1101/677229
https://doi.org/10.1101/677229
Publikováno v:
The EMBO Journal. 38
The small GTPase Rab7 is a key organizer of receptor sorting and lysosomal degradation by recruiting of a variety of effectors depending on its GDP/GTP‐bound state. However, molecular mechanisms that trigger Rab7 inactivation remain elusive. Here w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03d7a6bd52bcc9f45e1ef9a9959a311
https://doi.org/10.15252/embj.2018100312
https://doi.org/10.15252/embj.2018100312
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1949
Non-vesicular lipid transport via lipid transfer proteins (LTPs) at membrane contact sites (MCSs) is critical for the maintenance of the lipid composition of biological membranes. The ability to measure lipid transfer activity of diverse LTPs in live
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8cc687543bfdfbe4bdfc0184e3f9131d
https://pubmed.ncbi.nlm.nih.gov/30790245
https://pubmed.ncbi.nlm.nih.gov/30790245
Publikováno v:
Methods in Molecular Biology ISBN: 9781493991358
Non-vesicular lipid transport via lipid transfer proteins (LTPs) at membrane contact sites (MCSs) is critical for the maintenance of the lipid composition of biological membranes. The ability to measure lipid transfer activity of diverse LTPs in live
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::202658f30617ccbaf444fadc4c248acd
https://doi.org/10.1007/978-1-4939-9136-5_2
https://doi.org/10.1007/978-1-4939-9136-5_2
Publikováno v:
Cell calcium. 64
One of the largest challenges in cell biology is to map the lipid composition of the membranes of various organelles and define the exact location of processes that control the synthesis and distribution of lipids between cellular compartments. The c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1961fb621a8f367974135ac0954f58a9
https://pubmed.ncbi.nlm.nih.gov/28088320
https://pubmed.ncbi.nlm.nih.gov/28088320
Autor:
H. Alex Brown, Mira Sohn, Pavlina T. Ivanova, Daniel J Toth, Péter Várnai, Tamas Balla, Yeun Ju Kim
Lenz-Majewski syndrome (LMS) is a rare disease characterized by complex craniofacial, dental, cutaneous, and limb abnormalities combined with intellectual disability. Mutations in thePTDSS1gene coding one of the phosphatidylserine (PS) synthase enzym
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fd7dce5ce23fd1a1a602bbab2caf5d
https://europepmc.org/articles/PMC4843478/
https://europepmc.org/articles/PMC4843478/
Autor:
Daniel J Toth, Martin Klima, Petr Man, Lenka Rezabkova, Rozálie Hexnerová, Adriana Baumlova, Vaclav Veverka, Evzen Boura, Nivedita Sengupta, Radim Nencka, Anna Dubankova, Dominika Chalupska, Jan Tykvart, Tamas Balla, Jana Humpolíčková
Publikováno v:
Scientific Reports
Phosphatidylinositol 4-kinase beta (PI4KB) is one of four human PI4K enzymes that generate phosphatidylinositol 4-phosphate (PI4P), a minor but essential regulatory lipid found in all eukaryotic cells. To convert their lipid substrates, PI4Ks must be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8352c0c1082ac0cfa6d774174e0148
https://doi.org/10.1038/srep23641
https://doi.org/10.1038/srep23641
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d26e9fb594f107a62fddc1d2463726b1
https://doi.org/10.1530/endoabs.35.p737
https://doi.org/10.1530/endoabs.35.p737
Autor:
Szilvia Barsi, Henrietta Papp, Alberto Valdeolivas, Dániel J Tóth, Anett Kuczmog, Mónika Madai, László Hunyady, Péter Várnai, Julio Saez-Rodriguez, Ferenc Jakab, Bence Szalai
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 4, p e1010021 (2022)
Comparing SARS-CoV-2 infection-induced gene expression signatures to drug treatment-induced gene expression signatures is a promising bioinformatic tool to repurpose existing drugs against SARS-CoV-2. The general hypothesis of signature-based drug re
Externí odkaz:
https://doaj.org/article/ead04c612c984d5d8cd52b9ab306ee11