Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Daniel J Liebl"'
Autor:
Hua Wang, Zhiyou Peng, Yiwen Li, James J. Sahn, Timothy R. Hodges, Tsung-Han Chou, Qiong Liu, Xuezhi Zhou, Shuliang Jiao, Vittorio Porciatti, Daniel J. Liebl, Stephen F. Martin, Rong Wen
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract The sigma 2 receptor (σ2R) was recently identified as an endoplasmic reticulum (ER) membrane protein known as transmembrane protein 97 (TMEM97). Studies have shown that σ2R/TMEM97 binding compounds are neuroprotective, suggesting a role of
Externí odkaz:
https://doaj.org/article/1d3b2f964175428cacf0b3d8c79c728f
Autor:
Clara Penas, Marie E. Maloof, Vasileios Stathias, Jun Long, Sze Kiat Tan, Jose Mier, Yin Fang, Camilo Valdes, Jezabel Rodriguez-Blanco, Cheng-Ming Chiang, David J. Robbins, Daniel J. Liebl, Jae K. Lee, Mary E. Hatten, Jennifer Clarke, Nagi G. Ayad
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The mechanisms controlling irreversible cell cycle exit in cerebellar granule progenitors (GCPs) have not been fully elucidated. Here, the authors performed RNA-sequencing of GCPs exiting the cell cycle to identify downregulation of Brd4 activity as
Externí odkaz:
https://doaj.org/article/5d102d486ad049ca91e993219a553e49
Publikováno v:
Cell Death & Differentiation. 30:397-406
Hallmark pathological features of brain trauma are axonal degeneration and demyelination because myelin-producing oligodendrocytes (OLs) are particularly vulnerable to injury-induced death signals. To reveal mechanisms responsible for this OL loss, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8612d146269c990b64e5c4e49c775004
https://doi.org/10.1038/s41418-022-01091-z
https://doi.org/10.1038/s41418-022-01091-z
Autor:
Julien Laussu, Christophe Audouard, Anthony Kischel, Poincyane Assis-Nascimento, Nathalie Escalas, Daniel J. Liebl, Cathy Soula, Alice Davy
Publikováno v:
Neural Development, Vol 12, Iss 1, Pp 1-11 (2017)
Abstract Background In the vertebrate spinal cord, motor neurons (MN) are generated in stereotypical numbers from a pool of dedicated progenitors (pMN) whose number depends on signals that control their specification but also their proliferation and
Externí odkaz:
https://doaj.org/article/09cd3e2ef47446719fce0ccdaed61627
Autor:
Muhammad Saad Yousuf, James J. Sahn, Eric T. David, Stephanie Shiers, Danielle M. Royer, Chelsea D. Garcia, Jennifer Zhang, Veronica M. Hong, Ayesha Ahmad, Benedict J. Kolber, Daniel J Liebl, Stephen F. Martin, Theodore J. Price
The Sigma 2 receptor (σ2R) was described pharmacologically more than three decades ago, but its molecular identity remained obscure until recently when it was identified as transmembrane protein 97 (TMEM97). We and others have shown that σ2R/TMEM97
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15b418aee99984bd348deff7da78b005
https://doi.org/10.1101/2023.04.11.536439
https://doi.org/10.1101/2023.04.11.536439
Autor:
Enmanuel J. Perez, Maria L. Cepero, Sebastian U. Perez, Joseph T. Coyle, Thomas J. Sick, Daniel J. Liebl
Publikováno v:
Neurobiology of Disease, Vol 94, Iss , Pp 73-84 (2016)
Traumatic brain injury (TBI), ranging from mild concussion to severe penetrating wounds, can involve brain regions that contain damaged or lost synapses in the absence of neuronal death. These affected regions significantly contribute to sensory, mot
Externí odkaz:
https://doaj.org/article/fc4be2796f6348929b1686d61d01f8bc
Autor:
Stephen A. Tapanes, Dena Arizanovska, Madelen M. Díaz, Oluwarotimi O. Folorunso, Theresa Harvey, Stephanie E. Brown, Inna Radzishevsky, Liesl N. Close, Jonathan R. Jagid, Joacir Graciolli Cordeiro, Herman Wolosker, Darrick T. Balu, Daniel J. Liebl
Publikováno v:
Glia. 70:1133-1152
Synaptic damage is one of the most prevalent pathophysiological responses to traumatic CNS injury and underlies much of the associated cognitive dysfunction; however, it is poorly understood. The D-amino acid, D-serine, serves as the primary co-agoni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c18fbf3679c0df285f31eacd69680012
https://doi.org/10.1002/glia.24161
https://doi.org/10.1002/glia.24161
Autor:
Veronica Hong, Avaneesh Rade, Tarik Ehsan, Muhammad Saad Yousuf, Daniel J. Liebl, Theodore J. Price, Benedict J. Kolber
Publikováno v:
The Journal of Pain. 24:44
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b15bca7649ee06c9db8955fb5ec26d69
https://doi.org/10.1016/j.jpain.2023.02.136
https://doi.org/10.1016/j.jpain.2023.02.136
Autor:
Hua, Wang, Zhiyou, Peng, Yiwen, Li, James J, Sahn, Timothy R, Hodges, Tsung-Han, Chou, Qiong, Liu, Xuezhi, Zhou, Shuliang, Jiao, Vittorio, Porciatti, Daniel J, Liebl, Stephen F, Martin, Rong, Wen
Publikováno v:
Scientific reports. 12(1)
The sigma 2 receptor (σ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3f79d0cca13b851f0e9c7bfa58c2c693
https://pubmed.ncbi.nlm.nih.gov/36456686
https://pubmed.ncbi.nlm.nih.gov/36456686
Autor:
Hongmei Duan, Xiaoguang Li, Peng Hao, Liming Cheng, Yi E. Sun, Vance Lemmon, Junkui Shang, Yan Shi, Daniel J. Liebl, Agnes E. Haggerty, Zijue Wang, Martin Oudega, Jian Sun
Publikováno v:
Experimental Neurology. 312:51-62
It was previously reported that a tube holding chitosan carriers loaded with neurotrophin-3 (NT-3), after insertion into a 5 mm long transection gap in the adult rat spinal cord, triggered de novo neural tissue generation and functional recovery. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d850a2e0f4e2ebbb7c38f73147ba8ff
https://doi.org/10.1016/j.expneurol.2018.11.003
https://doi.org/10.1016/j.expneurol.2018.11.003