Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Daniel J Leong"'
Autor:
Calogera M Simonaro, Sylvain Sachot, Yi Ge, Xingxuan He, Victor A Deangelis, Efrat Eliyahu, Daniel J Leong, Hui B Sun, Jeffrey B Mason, Mark E Haskins, Dean W Richardson, Edward H Schuchman
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e62715 (2013)
Acid ceramidase is required to maintain the metabolic balance of several important bioactive lipids, including ceramide, sphingosine and sphingosine-1-phosphate. Here we show that addition of recombinant acid ceramidase (rAC) to primary chondrocyte c
Externí odkaz:
https://doaj.org/article/940af73a6bb0409b9315b0fd6ccc0445
Autor:
Jonathan Y Lee, Zuping Zhou, Peter J Taub, Melissa Ramcharan, Yonghui Li, Takintope Akinbiyi, Edward R Maharam, Daniel J Leong, Damien M Laudier, Takuya Ruike, Phillip J Torina, Mone Zaidi, Robert J Majeska, Mitchell B Schaffler, Evan L Flatow, Hui B Sun
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17531 (2011)
We characterized the differentiation of rat bone marrow-derived mesenchymal stem cells (BM-MSCs) into tenocyte-like cells in response to bone morphogenetic protein-12 (BMP-12). BM-MSCs were prepared from Sprague-Dawley rats and cultured as monolayers
Externí odkaz:
https://doaj.org/article/ae65fd77be85486589f50a62da92add4
Publikováno v:
Journal of Orthopaedic Translation, Vol 9, Iss C, Pp 69-75 (2017)
Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this article
Externí odkaz:
https://doaj.org/article/15091df6a4f14b4d86543a85d9519a8b
Autor:
Angela Wang Ilaltdinov, Hui B. Sun, Yubao Gong, Daniel J. Leong, Konrad I. Gruson, Deyou Zheng, Li Sun, David T. Fung
Publikováno v:
Annals of the New York Academy of SciencesReferences. 1490(1)
Tendinopathy is a common musculoskeletal disorder characterized by chronic low-grade inflammation and tissue degeneration. Tendons have poor innate healing ability and there is currently no cure for tendinopathy. Studies elucidating mechanisms underl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f18ebb5d5bc6f38ceb0530a517220f3
https://pubmed.ncbi.nlm.nih.gov/32501571
https://pubmed.ncbi.nlm.nih.gov/32501571
Publikováno v:
Annals of the New York Academy of Sciences. 1410:57-67
Exosomes are nanovesicles secreted from cells that play key roles in intercellular communication. They carry unique content derived from parental cells and are capable of transferring this cargo between cells. The role and function of exosomes largel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ddd2985e89c3080cfaa33006b10b6957
https://doi.org/10.1111/nyas.13469
https://doi.org/10.1111/nyas.13469
Publikováno v:
Journal of Orthopaedic Translation, Vol 9, Iss C, Pp 69-75 (2017)
Journal of Orthopaedic Translation
Journal of Orthopaedic Translation
Summary Tendon injuries are significant clinical problems. Current treatments often result in incomplete repair or healing, which may lead to reduced function and rupture. Stem cell-based therapy is a promising intervention for tendon repair. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34d70d91cbb4bf6b7d5de074ceb4818e
http://www.sciencedirect.com/science/article/pii/S2214031X16302844
http://www.sciencedirect.com/science/article/pii/S2214031X16302844
Autor:
David M. Hirsh, Lin Xu, Daniel J. Leong, Robert J. Majeska, Sun J. Kim, Zhiyong He, Hui B. Sun, Mary B. Goldring, Neil J. Cobelli, Lidi Liu, Haotian Feng, Laijin Lu
Publikováno v:
Annals of the New York Academy of Sciences. 1442(1)
Adipokines secreted from the infrapatellar fat pad (IPFP), such as adipsin and adiponectin, have been implicated in osteoarthritis pathogenesis. CITED2, a mechanosensitive transcriptional regulator with chondroprotective activity, may modulate their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3ed5156125c2c64ef6c0c45be5e70f
https://pubmed.ncbi.nlm.nih.gov/30891782
https://pubmed.ncbi.nlm.nih.gov/30891782
Autor:
David M. Hirsh, Sun Jin Kim, Regina Hanstein, Marwa Choudhury, Mitchell B. Schaffler, Daniel J. Leong, Neil J. Cobelli, Mary B. Goldring, Robert J. Majeska, Hui B. Sun, John A. Hardin, David C. Spray
Publikováno v:
Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-1 (2019)
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-1 (2019)
Following publication of the original article [1], the authors reported an error in Figs. 2C and 5C.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8234f6e75070eb067970c92d3cb79f64
https://doi.org/10.1186/s13075-018-1791-9
https://doi.org/10.1186/s13075-018-1791-9
Autor:
Hui B. Sun, Daniel J. Leong
Publikováno v:
Annals of the New York Academy of Sciences. 1383:88-96
Tendon injuries are common and present a clinical challenge because they often respond poorly to treatment and require prolonged rehabilitation. Current treatments often do not completely repair or regenerate the injured or diseased tendon to its nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e3a6738f33536f4639795e59eb6fa36
https://doi.org/10.1111/nyas.13262
https://doi.org/10.1111/nyas.13262