Výsledky vyhledávání - "Daniel J Kostyniuk"

Akademický článek

Social status regulates the hepatic miRNAome in rainbow trout: Implications for posttranscriptional regulation of metabolic pathways.

Autor: Daniel J Kostyniuk, Dapeng Zhang, Christopher J Martyniuk, Kathleen M Gilmour, Jan A Mennigen

Publikováno v: PLoS ONE, Vol 14, Iss 6, p e0217978 (2019)

Juvenile rainbow trout develop social hierarchies when held in dyads, and the development of socially subordinate (SS) and social dominance (SD) phenotypes in this context has been linked to specific changes in the hepatic energy metabolism of all ma

Externí odkaz: https://doaj.org/article/f439d74e5929471cbb222928f539421c

Zobrazit plný text záznamu

Plný text ve formátu HTML

Chronic social stress alters protein metabolism in juvenile rainbow trout, Oncorhynchus mykiss

Autor: Simon G. Lamarre, Kathleen M. Gilmour, Daniel J. Kostyniuk, Roxanne J. Saulnier, Carol Best

Publikováno v: Journal of Comparative Physiology. B, Biochemical, Systemic, and Environmental Physiology

When confined in pairs, juvenile rainbow trout (Oncorhynchus mykiss) form dominance hierarchies in which subordinate fish exhibit characteristic physiological changes including reduced growth rates and chronically elevated plasma cortisol concentrati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbda7383f9041c886c68c9e0046665b4
https://doi.org/10.1007/s00360-021-01340-6

Zobrazit plný text záznamu

Genetic ablation of bone marrow beta-adrenergic receptors in mice modulates miRNA-transcriptome networks of neuroinflammation in the paraventricular nucleus

Autor: Jan A. Mennigen, Ruben Martinez, Christopher J. Martyniuk, Daniel J. Kostyniuk, Jasenka Zubcevic

Publikováno v: Physiol Genomics
Digital.CSIC. Repositorio Institucional del CSIC
instname

Elucidating molecular pathways regulating neuroimmune communication is critical for therapeutic interventions in conditions characterized by overactive immune responses and dysfunctional autonomic nervous system. We generated a bone marrow-specific a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f7dfb79fc80d9a1c9d5440099c1eab5
https://doi.org/10.1152/physiolgenomics.00001.2020

Zobrazit plný text záznamu

Bioconcentration and Metabolic Effects of Emerging PFOS Alternatives in Developing Zebrafish

Autor: Daniel J. Kostyniuk, Jan A. Mennigen, Christine Hum, Yuanxiang Jin, Wenqing Tu, Laia Navarro-Martín, Jing Huang, Hing Man Chan, Ruben Martinez, Mi Deng

Publikováno v: Environmental Science & Technology
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona

The novel PFOS alternatives, 6:2 chlorinated polyfluorinated ether sulfonate (F-53B) and sodium p-perfluorous nonenoxybenzenesulfonate (OBS), are emerging in the Chinese market, but little is known about their ecological risks. In this study, zebrafi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba24590cf28a3dedd2a15f1470af525f
https://doi.org/10.1021/acs.est.9b03820

Zobrazit plný text záznamu

Toxicokinetics and toxic effects of a Chinese PFOS alternative F-53B in adult zebrafish

Autor: Hailin You, Mi Deng, Xiyan Mu, Xiaoli He, Wu Yongming, Wenqing Tu, Zhaohuan Mai, Yuanxiang Jin, Reem Al-harthi, Yang Chunyan, Xin Liu, Daniel J. Kostyniuk

Publikováno v: Ecotoxicology and Environmental Safety. 171:460-466

6:2 chlorinated polyfluorinated ether sulfonate (F-53B), a Chinese PFOS alternative, has recently been identified in river water, sewage sludge, wildlife and humans, causing great concerns about its potential toxic effects. Here, we report the first

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17f08bf8023f53a0244aa0ade5bd0864
https://doi.org/10.1016/j.ecoenv.2019.01.010

Zobrazit plný text záznamu

Unexpected effect of insulin on glucose disposal explains glucose intolerance of rainbow trout

Autor: Jan A. Mennigen, Daniel J. Kostyniuk, Jean-Michel Weber, Johnathon L. I. Forbes

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 316:R387-R394

The physiological reasons why salmonids show glucose intolerance are unclear. In mammals, rapid clearance of a glucose load is mainly achieved through insulin-mediated inhibition of hepatic glucose production ( Ra) and stimulation of glucose disposal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b01af7593ced740199781c8b41473d04
https://doi.org/10.1152/ajpregu.00344.2018

Zobrazit plný text záznamu

Meta-analysis of differentially-regulated hepatic microRNAs identifies candidate post-transcriptional regulation networks of intermediary metabolism in rainbow trout

Autor: Daniel J. Kostyniuk, Jan A. Mennigen

Publikováno v: Comparative biochemistry and physiology. Part D, Genomicsproteomics. 36

MicroRNAs (miRNAs) are small non-coding RNAs which act as post-transcriptional regulators by decreasing targeted mRNA translation and stability. Principally targeting small 3' UTR elements of protein-coding mRNAs through complementary base-pairing, m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::249d81be1a1d1f8d99949c916384694d
https://pubmed.ncbi.nlm.nih.gov/33038710

Zobrazit plný text záznamu

Social status affects lipid metabolism in rainbow trout,Oncorhynchus mykiss

Autor: Brett M. Culbert, Jan A. Mennigen, Daniel J. Kostyniuk, Kathleen M. Gilmour

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 315:R241-R255

Juvenile rainbow trout ( Oncorhynchus mykiss) confined in pairs form social hierarchies in which socially subordinate fish display characteristic traits, including reduced growth rates and altered glucose metabolism. These effects are, in part, media

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51b99ca4e6cda436e74c136e80c7b50f
https://doi.org/10.1152/ajpregu.00402.2017

Zobrazit plný text záznamu

Pck-ing up steam: widening the salmonid gluconeogenic gene duplication trail

Autor: Jan A. Mennigen, Lucie Marandel, Stéphane Panserat, Jingwei Liu, Johnathon L. I. Forbes, Carol Best, Daniel J. Kostyniuk

Publikováno v: Gene
Gene, Elsevier, 2019, 698, pp.129-140. ⟨10.1016/j.gene.2019.02.079⟩
Gene, 2019, 698, pp.129-140. ⟨10.1016/j.gene.2019.02.079⟩

Rainbow trout have, as salmonid fish species, undergone sequential genome duplication events in their evolutionary history. In addition to a teleost-specific whole genome duplication approximately 320–350 million years ago, rainbow trout and salmon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7922b2895523d131aa04f73e6654aa26
https://hal.archives-ouvertes.fr/hal-02083273

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání