Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Daniel J Hui"'
Autor:
Daniel J Hui, Shyrie C Edmonson, Gregory M Podsakoff, Gary C Pien, Lacramioara Ivanciu, Rodney M Camire, Hildegund Ertl, Federico Mingozzi, Katherine A High, Etiena Basner-Tschakarjan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
Adeno-associated virus (AAV) has become one of the most promising vectors in gene transfer in the last 10 years with successful translation to clinical trials in humans and even market approval for a first gene therapy product in Europe. Administrati
Externí odkaz:
https://doaj.org/article/c3c459a322e749a9b9b077cc70a13749
Autor:
Xavier M. Anguela, Katie Wachtel, Judith Kadosh, Stacy E. Croteau, Marcus E. Carr, Lindsey A. George, Leonard A. Valentino, Matthew S. Evans, Federico Mingozzi, Linda B. Couto, Daniel Takefman, Kathleen B Reape, Daniel J. Hui, Alexa R. Runoski, Amy Macdougall, Katherine A. High, Cynthia Campbell-Baird, Marcelyne Joseney-Antoine, Ben J. Samelson-Jones, Howard Hait, Summer Tompkins, Spencer K. Sullivan, Ashlyn Eaton Bassiri, M. Elaine Eyster, Kayla Douglas, Margaret V. Ragni
Publikováno v:
Blood. 132:487-487
Gene transfer for hemophilia A offers the potential for a one-time disease altering treatment, eliminating the risk of bleeds while freeing patients from the burden of lifelong chronic therapy. SPK-8011 consists of a bioengineered AAV capsid expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b9ceb3979e02dffcffbb36210b302ec
https://doi.org/10.1182/blood-2018-99-115495
https://doi.org/10.1182/blood-2018-99-115495
Autor:
Shyrie Edmonson, Denise E. Sabatino, Katherine A. High, Hojun Li, Federico Mingozzi, Samuel L. Murphy, Daniel J. Hui
Publikováno v:
Journal of Medical Virology. 81:65-74
Humoral immune responses occur following exposure to Adeno-associated virus (AAV) or AAV vectors. Many studies characterized antibody responses to AAV, but human IgG subclass responses to AAV have not been previously described. In this study, IgG sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02baa7b7d3a60e84f00638a9c8744688
https://doi.org/10.1002/jmv.21360
https://doi.org/10.1002/jmv.21360
Autor:
Denise E. Sabatino, Jurg M. Sommer, Margaret V. Ragni, Catherine S. Manno, Hildegund C.J. Ertl, Katherine A. High, Glenn Pierce, John E.J. Rasko, Haiyan Jiang, Marcela V. Maus, Daniel J. Hui, Federico Mingozzi, Samuel L. Murphy
Publikováno v:
Nature Medicine. 13:419-422
Hepatic adeno-associated virus (AAV)-serotype 2 mediated gene transfer results in transgene product expression that is sustained in experimental animals but not in human subjects. We hypothesize that this is caused by rejection of transduced hepatocy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2f13aa92441e09cac1ac1cb3fe312c
https://doi.org/10.1038/nm1549
https://doi.org/10.1038/nm1549
Publikováno v:
Journal of Biological Chemistry. 281:34064-34071
Human P54 and P56 proteins are tetratricopeptide proteins that are encoded by two closely related genes, ISG54 and ISG56. These genes are induced strongly but transiently when cells are treated with interferons or double-stranded RNA or infected with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db025ead88d61eecdb1af2b0bb7eb289
https://doi.org/10.1074/jbc.m605771200
https://doi.org/10.1074/jbc.m605771200
Publikováno v:
Journal of Biological Chemistry. 280:3433-3440
Members of the p56 family of mammalian proteins are strongly induced in virus-infected cells and in cells treated with interferons or double-stranded RNA. Previously, we have reported that human p56 inhibits initiation of translation by binding to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c834c3a6228a7b59e63483492bfbfc
https://doi.org/10.1074/jbc.m406700200
https://doi.org/10.1074/jbc.m406700200
Autor:
Jean Bennett, Yifeng Chen, Romuald Corbau, Daniel J. Hui, Stephen R. Russell, Thomas Antrilli, Yun Liu, Katherine A. High, Albert M. Maguire
Publikováno v:
Molecular Therapy. 24:S72-S73
Mutations in the gene encoding Retinal Pigment Epithelium-Specific Protein 65 (RPE65) cause impaired vision from an early age and eventually total vision loss later in life. Recent work by our group and others demonstrated the use of SPK-RPE65, an ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dca1309b53778515f9e9af973d5685e9
https://doi.org/10.1016/s1525-0016(16)32994-x
https://doi.org/10.1016/s1525-0016(16)32994-x
Autor:
Federico Mingozzi, Daniel J. Hui, Hildegund C.J. Ertl, Shyrie C Edmonson, Rodney M. Camire, Etiena Basner-Tschakarjan, Lacramioara Ivanciu, Katherine A. High, Gregory M. Podsakoff, Gary C. Pien
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss, Pp-(2015)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Adeno-associated virus (AAV) has become one of the most promising vectors in gene transfer in the last 10 years with successful translation to clinical trials in humans and even market approval for a first gene therapy product in Europe. Administrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd0ffba287b2b6e221a827ff93f4258
Publikováno v:
The EMBO Journal. 19:6891-6899
We report a new pathway of translation regulation that may operate in interferon‐treated or virus‐infected mammalian cells. This pathway is activated by P56, a protein whose synthesis is strongly induced by interferons or double‐stranded RNA. U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d55fe562bd2164ada98278c687e6920
https://doi.org/10.1093/emboj/19.24.6891
https://doi.org/10.1093/emboj/19.24.6891
Autor:
Alex Tai, Federico Mingozzi, J F Wright, Carolann Howard, Daniel J. Hui, Giulia Pavani, Christian Hinderer, Yifeng Chen, Xavier M. Anguela, Gregory M. Podsakoff, Liron Elkouby, Armida Faella, Robert J. Davidson, Shangzhen Zhou, Etiena Basner-Tschakarjan, Katherine A. High, Mustafa N. Yazicioglu
Publikováno v:
Sci Transl Med
Sci Transl Med, 2013, 5 (194), pp.194ra92. ⟨10.1126/scitranslmed.3005795⟩
Sci Transl Med, 2013, 5 (194), pp.194ra92. ⟨10.1126/scitranslmed.3005795⟩
International audience; Adeno-associated virus (AAV) vectors delivered through the systemic circulation successfully transduce various target tissues in animal models. However, similar attempts in humans have been hampered by the high prevalence of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c78c7b567348c1e6cc35478e67f6de4
https://hal.archives-ouvertes.fr/hal-02881152
https://hal.archives-ouvertes.fr/hal-02881152
