Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Daniel J Goetschius"'
Autor:
Matthew D Lauver, Daniel J Goetschius, Colleen S Netherby-Winslow, Katelyn N Ayers, Ge Jin, Daniel G Haas, Elizabeth L Frost, Sung Hyun Cho, Carol M Bator, Stephanie M Bywaters, Neil D Christensen, Susan L Hafenstein, Aron E Lukacher
Publikováno v:
eLife, Vol 9 (2020)
JCPyV polyomavirus, a member of the human virome, causes progressive multifocal leukoencephalopathy (PML), an oft-fatal demyelinating brain disease in individuals receiving immunomodulatory therapies. Mutations in the major viral capsid protein, VP1,
Externí odkaz:
https://doaj.org/article/49ff0ad1d7a649d79e8ecf95bda3fe2f
Autor:
Timothy Jegla, Michelle M Nguyen, Chengye Feng, Daniel J Goetschius, Esteban Luna, Damian B van Rossum, Bishoy Kamel, Aditya Pisupati, Elliott S Milner, Melissa M Rolls
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006457 (2016)
In vertebrate neurons, the axon initial segment (AIS) is specialized for action potential initiation. It is organized by a giant 480 Kd variant of ankyrin G (AnkG) that serves as an anchor for ion channels and is required for a plasma membrane diffus
Externí odkaz:
https://doaj.org/article/7363b8380f3c40e1a46cb9b9312dce9d
Autor:
Andrew J. Charnesky, Julia E. Faust, Hyunwook Lee, Rama Devudu Puligedda, Daniel J. Goetschius, Nadia M. DiNunno, Vaskar Thapa, Carol M. Bator, Sung Hyun (Joseph) Cho, Rahnuma Wahid, Kutub Mahmood, Scott Dessain, Konstantin M. Chumakov, Amy Rosenfeld, Susan L. Hafenstein
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Global eradication of poliovirus remains elusive, and it is critical to develop next generation vaccines and antivirals. In support of this goal, we map the epitope of human monoclonal antibody 9H2 which is able to neutralize the three serot
Externí odkaz:
https://doaj.org/article/9fd2243b86754c1196621e07354a248f
Autor:
Daniel J. Goetschius, Samantha R. Hartmann, Suriyasri Subramanian, Carol M. Bator, Neil D. Christensen, Susan L. Hafenstein
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Human papillomavirus (HPV) is a significant health burden and leading cause of virus-induced cancers. HPV is epitheliotropic and its replication is tightly associated with terminal keratinocyte differentiation making production and purificat
Externí odkaz:
https://doaj.org/article/e04b64485e644667b0e59a3751e54ebe
Autor:
Nadia M. DiNunno, Daniel J. Goetschius, Anoop Narayanan, Sydney A. Majowicz, Ibrahim Moustafa, Carol M. Bator, Susan L. Hafenstein, Joyce Jose
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
Here, the authors provide a 3.4 Å resolution structure of mature Zika virus (ZIKV) and identify two lipid moieties, coordinated by hydrophobic residues of the M and E transmembrane helices and between two helices of E protein, that play an essential
Externí odkaz:
https://doaj.org/article/7496445a4f9c45ed87e234236a9b0144
Autor:
Samantha R. Hartmann, Daniel J. Goetschius, Jiafen Hu, Joshua J. Graff, Carol M. Bator, Neil D. Christensen, Susan L. Hafenstein
Publikováno v:
Viruses, Vol 13, Iss 10, p 2023 (2021)
Human papillomavirus (HPV) is a significant health burden and leading cause of virus-induced cancers. However, studies have been hampered due to restricted tropism that makes production and purification of high titer virus problematic. This issue has
Externí odkaz:
https://doaj.org/article/fc77a8772a78492a91c40dfcca533a5e
Autor:
Robert A. López-Astacio, Oluwafemi F. Adu, Daniel J. Goetschius, Hyunwook Lee, Wendy S. Weichert, Brian R. Wasik, Simon P. Frueh, Brynn K. Alford, Ian E.H. Voorhees, Joseph F. Flint, Sarah Saddoris, Laura B. Goodman, Edward C. Holmes, Susan L. Hafenstein, Colin R. Parrish
Publikováno v:
bioRxiv
Canine parvovirus (CPV) is a small non-enveloped single-stranded DNA virus that causes serious diseases in dogs worldwide. The original strain of the virus (CPV-2) emerged in dogs during the late-1970s due to a host range switch of a virus similar to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2accdbf1599fd60b50108daaf84f01
https://doi.org/10.1128/jvi.00090-23
https://doi.org/10.1128/jvi.00090-23
Publikováno v:
Journal of clinical medicine. 11(4)
Since the emergence of SARS-CoV-2, several studies have been published describing neuromuscular manifestations of the disease, as well as management of pre-existing pediatric neuromuscular disorders during the COVID-19 pandemic. These disorders inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c925643b064855e0f913594cf4c138af
https://pubmed.ncbi.nlm.nih.gov/35207206
https://pubmed.ncbi.nlm.nih.gov/35207206
Autor:
Carol M. Bator, Neil D. Christensen, Samantha R. Hartmann, Joshua J. Graff, Susan Hafenstein, Jiafen Hu, Daniel J. Goetschius
Publikováno v:
Viruses
Volume 13
Issue 10
Viruses, Vol 13, Iss 2023, p 2023 (2021)
Volume 13
Issue 10
Viruses, Vol 13, Iss 2023, p 2023 (2021)
Human papillomavirus (HPV) is a significant health burden and leading cause of virus-induced cancers. However, studies have been hampered due to restricted tropism that makes production and purification of high titer virus problematic. This issue has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e0ea70f2db617b0083736985817e953
Autor:
James F. Conway, Carol M. Bator, Daniel J. Goetschius, Susan Hafenstein, Robert E. Ashley, Alexander M. Makhov, Kai Huang, Lindsey J. Organtini, Samantha R. Hartmann, Colin R. Parrish, Heather M. Callaway
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Our study makes significant progress understanding asymmetry in icosahedral viruses that would be otherwise masked by forcing homogeneity through icosahedral averaging. Using an asymmetric approach revealed the atomic-resolution structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba536fc1069fb3cb0d1ab0a560d54900
https://doi.org/10.1073/pnas.2025452118
https://doi.org/10.1073/pnas.2025452118