Zobrazeno 1 - 10
of 262
pro vyhledávání: '"Daniel J Garry"'
Autor:
Alessandro Magli, June Baik, Lauren J Mills, Il-Youp Kwak, Bridget S Dillon, Ricardo Mondragon Gonzalez, David A Stafford, Scott A Swanson, Ron Stewart, James A Thomson, Daniel J Garry, Brian D Dynlacht, Rita C R Perlingeiro
Publikováno v:
PLoS Biology, Vol 17, Iss 2, p e3000153 (2019)
The transcriptional mechanisms driving lineage specification during development are still largely unknown, as the interplay of multiple transcription factors makes it difficult to dissect these molecular events. Using a cell-based differentiation pla
Externí odkaz:
https://doaj.org/article/09304123793a415cb5a26e79fc1ee488
Autor:
Bhairab N Singh, Naoyuki Tahara, Yasuhiko Kawakami, Satyabrata Das, Naoko Koyano-Nakagawa, Wuming Gong, Mary G Garry, Daniel J Garry
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189010 (2017)
Remodeling of the primitive vasculature is necessary for the formation of a complex branched vascular architecture. However, the factors that modulate these processes are incompletely defined. Previously, we defined the role of microRNAs (miRNAs) in
Externí odkaz:
https://doaj.org/article/5f952302b3da4393b3be6148dfa367d4
Autor:
Il-Youp Kwak, Byeong-Chan Kim, Juhyun Lee, Taein Kang, Daniel J. Garry, Jianyi Zhang, Wuming Gong
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract The breakthrough high-throughput measurement of the cis-regulatory activity of millions of randomly generated promoters provides an unprecedented opportunity to systematically decode the cis-regulatory logic that determines the expression va
Externí odkaz:
https://doaj.org/article/0af5c93b8a9a47479bfdcf64431a6871
Autor:
Tara L Rasmussen, Xiaozhong Shi, Alicia Wallis, Junghun Kweon, Katie M Zirbes, Naoko Koyano-Nakagawa, Daniel J Garry
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50103 (2012)
Previous reports regarding the genetic hierarchy between Ets related protein 71 (Er71/Etv2) and Flk1 is unclear. In the present study, we pursued a genetic approach to define the molecular cascade between Etv2 and Flk1. Using a transgenic Etv2-EYFP r
Externí odkaz:
https://doaj.org/article/56d3b41387704585a221bc05db56cdd2
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2024)
Background: In our previous work, we demonstrated that when newborn pigs undergo apical resection (AR) on postnatal day 1 (P1), the animals’ hearts were completely recover from a myocardial infarction (MI) that occurs on postnatal day 28 (P28); sin
Externí odkaz:
https://doaj.org/article/541c7367a971495d957b3e841860f549
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-28 (2023)
Abstract Assay for Transposase-Accessible Chromatin with sequencing (ATAC-seq) reveals chromatin accessibility across the genome. Currently, no method specifically detects differential chromatin accessibility. Here, SeATAC uses a conditional variatio
Externí odkaz:
https://doaj.org/article/d56d0fbeef97442287bbd3c39241eadc
Autor:
Naoko Koyano-Nakagawa, Wuming Gong, Satyabrata Das, Joshua W. M. Theisen, Tran B. Swanholm, Daniel Van Ly, Nikita Dsouza, Bhairab N. Singh, Hiroko Kawakami, Samantha Young, Katherine Q. Chen, Yasuhiko Kawakami, Daniel J. Garry
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
The embryonic limb bud is known to be patterned by a Shh morphogen gradient, though how Shh expression is activated remains less clear. Here the authors show that Etv2 acts as a pioneer transcription factor to mediate accessibility of the ZRS enhance
Externí odkaz:
https://doaj.org/article/78037045b7d940fa8cf10e68eb7f55dd
Autor:
Satyabrata Das, Vinayak Gupta, Johannes Bjorge, Xiaozhong Shi, Wuming Gong, Mary G. Garry, Daniel J. Garry
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Ets variant 2 (Etv2), a member of the Ets factor family, has an essential role in the formation of endothelial and hematopoietic cell lineages during embryonic development. The functional role of ETS transcription factors is, in part, dependent on th
Externí odkaz:
https://doaj.org/article/ab072e7171734121a591fca05cfc9b52
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The only curative therapy for many endstage diseases is allograft organ transplantation. Due to the limited supply of donor organs, relatively few patients are recipients of a transplanted organ. Therefore, new strategies are warranted to address thi
Externí odkaz:
https://doaj.org/article/1b29c1d6a6d74d5c846bc0906d9c4178
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 20 (2022)
Arrhythmogenic cardiovascular disorders are associated with considerable morbidity and mortality. Whether cardiac conduction disease is caused by genetic defects, procedural perturbations, valvular disease, ischemia, aging, or heart failure, new ther
Externí odkaz:
https://doaj.org/article/c24391fe2bfa433c9fec2046c3a5f3e0