Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Daniel J, Watson"'
Autor:
Kudakwashe Nyambo, Kudzanai Ian Tapfuma, Francis Adu-Amankwaah, Lauren Julius, Lucinda Baatjies, Idah Sithole Niang, Liezel Smith, Krishna Kuben Govender, Mkhuseli Ngxande, Daniel J. Watson, Lubbe Wiesner, Vuyo Mavumengwana
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Mycobacterial pathogens present a significant challenge to disease control efforts globally due to their inherent resistance to multiple antibiotics. The rise of drug-resistant strains of Mycobacterium tuberculosis has prompted an urgent nee
Externí odkaz:
https://doaj.org/article/b8563afc745148a48427cba5035c4cef
Autor:
Daniel J. Watson, Lizahn Laing, Jacobus P. Petzer, Ho Ning Wong, Christopher J. Parkinson, Lubbe Wiesner, Richard K. Haynes
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2024)
Efforts to develop new artemisinin triple combination therapies effective against artemisinin-tolerant strains of Plasmodium falciparum based on rational combinations comprising artemisone or other amino-artemisinins, a redox active drug and a third
Externí odkaz:
https://doaj.org/article/f0b32b20533b40e5ab69e8781098f068
Autor:
Daniel J. Watson, Lizahn Laing, Richard M. Beteck, Liezl Gibhard, Richard K. Haynes, Lubbe Wiesner
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The emergence of Plasmodium falciparum (Pf) parasite strains tolerant of the artemisinin component and resistant to the other drug component in artemisinin combination therapies (ACTs) used for treatment now markedly complicates malaria control. Thus
Externí odkaz:
https://doaj.org/article/0fa9857392ad4a1886dbda6556e86f19
Publikováno v:
Molecules, Vol 28, Iss 11, p 4276 (2023)
Novel antitubercular compounds are urgently needed to combat drug-resistant Mycobacterium tuberculosis (Mtb). Filamentous actinobacteria have historically been an excellent source of antitubercular drugs. Despite this, drug discovery from these micro
Externí odkaz:
https://doaj.org/article/6a575b253fad4636bd0da2a894d639f7
Autor:
Willy V. Bonneuil, Daniel J. Watson, Jennifer Frattolin, Matthew J. Russell, Francesca Fasanella Masci, Mikaila Bandara, Bindi S. Brook, Robert J. B. Nibbs, James E. Moore Jr.
Publikováno v:
AIP Advances, Vol 12, Iss 2, Pp 025121-025121-14 (2022)
Physiologic chemoattractant gradients are shaped by diffusion, advection, binding to an extracellular matrix, and removal by cells. Previous in vitro tools for studying these gradients and the cellular migratory response have required cells to be con
Externí odkaz:
https://doaj.org/article/b28f91c2c68b4ffda9fd940e5efdd89c
Autor:
Michael Madekurozwa, Willy V. Bonneuil, Jennifer Frattolin, Daniel J. Watson, Axel C. Moore, Molly M. Stevens, James Moore, Jakob Mathiszig-Lee, Joseph van Batenburg-Sherwood
Publikováno v:
Frontiers in Medical Technology, Vol 3 (2021)
There has existed a severe ventilator deficit in much of the world for many years, due in part to the high cost and complexity of traditional ICU ventilators. This was highlighted and exacerbated by the emergence of the COVID-19 pandemic, during whic
Externí odkaz:
https://doaj.org/article/cc607321c3dc4eb884526c93ea3313d1
Autor:
Donald L. Goss, Daniel J. Watson, Erin M. Miller, Amy N. Weart, Eliza B. Szymanek, Gregory M. Freisinger
Publikováno v:
Frontiers in Sports and Active Living, Vol 3 (2021)
A rearfoot strike (RFS) pattern with increased average vertical loading rates (AVLR) while running has been associated with injury. This study evaluated the ability of an instrumented sock, which provides real-time foot strike and cadence audio biofe
Externí odkaz:
https://doaj.org/article/c3220778d14e4ee6915fce494cab6eaa
Publikováno v:
Case Reports in Ophthalmology, Vol 9, Iss 1, Pp 82-92 (2018)
Purpose: To report the association of optic nerve head (ONH) drusen with Best vitelliform macular dystrophy (BVMD). Methods: Chart review. Patients: Five patients from 3 families. Results: Multimodal imaging and ophthalmic examination demonstrated fi
Externí odkaz:
https://doaj.org/article/a61420ae42114df9a1c458d4e7df84c2
Autor:
Jennifer Frattolin, Daniel J. Watson, Willy V. Bonneuil, Matthew J. Russell, Francesca Fasanella Masci, Mikaila Bandara, Bindi S. Brook, Robert J. B. Nibbs, James E. Moore
Publikováno v:
Cells, Vol 10, Iss 12, p 3439 (2021)
Intravital microscopy and other direct-imaging techniques have allowed for a characterisation of leukocyte migration that has revolutionised the field of immunology, resulting in an unprecedented understanding of the mechanisms of immune response and
Externí odkaz:
https://doaj.org/article/63448ba70e68496cb2a64fb9af9f17c3
Autor:
Daniel J. Watson, Paul R. Meyers, Kojo Sekyi Acquah, Godwin A. Dziwornu, Christopher Bevan Barnett, Lubbe Wiesner
Publikováno v:
Molecules, Vol 26, Iss 24, p 7494 (2021)
With drug resistance threatening our first line antimalarial treatments, novel chemotherapeutics need to be developed. Ionophores have garnered interest as novel antimalarials due to their theorized ability to target unique systems found in the Plasm
Externí odkaz:
https://doaj.org/article/408f72dae83d4eada707bf4935a990e7